Results 161 to 170 of about 10,976 (205)

Efficacy of Japanese Maca Powder Against Aging Stress in Human Dermal Fibroblasts. [PDF]

Int J Mol Sci
Dan K, Takanashi K, Kitamura S.
europepmc   +1 more source

Genetische Studie zum Cobalamin-Mangel beim Chinesischen Shar-Pei

, 2011
Grützner, Niels
core  

Epigenetic Regulation of Hyaluronan-Associated Genes in the Brain: Identifying Key Regulatory Sites. [PDF]

Epigenomes
Acevedo RE, Walton E, Mifsud KR.
europepmc   +1 more source

Lymphatic disruption drives lung transplant fibrosis through interleukin-1-mediated hyaluronan accumulation. [PDF]

Sci Transl Med
Shepherd HM, Li W, Kopecky BJ, Terada Y, Liu CR, Liu Z, Lee DD, Mineura K, Dun H, Yokoyama Y, Wong BW, Kurtoglu GK, Amrute JM, Scozzi D, Bai YZ, Bery AI, Bernadt CT, Ritter JH, Brody SL, Byers DE, Krupnick AS, Nava RG, Patterson GA, Puri V, Gelman AE, Lavine KJ, Randolph GJ, Kreisel D.   +27 more
europepmc   +1 more source

Quantitative continuous assay for hyaluronan synthase [PDF]

Analytical Biochemistry, 2007
A rapid, continuous, and convenient three-enzyme coupled UV absorption assay was developed to quantitate the glucuronic acid and N-acetylglucosamine transferase activities of hyaluronan synthase from Pasteurella multocida (PmHAS). Activity was measured by coupling the UDP produced from the PmHAS-catalyzed transfer of UDP-GlcNAc and UDP-GlcUA to a ...
Joanne C Krupa, Lianli Chi, Robert J Linhardt   +2 more
exaly   +5 more sources

Coding Sequence of a Hyaluronan Synthase Homologue Expressed during Expansion of the Mouse Cumulus–Oocyte Complex

Archives of Biochemistry and Biophysics, 1997
Maturation of mammalian cumulus cell-oocyte complex in the preovulatory follicle involves the deposition of a hyaluronan-rich extracellular matrix by the cumulus cells.
Csaba Fülöp, Antonietta Salustri, Vincent C Hascall   +2 more
exaly   +2 more sources

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Phosphorylation of Thr328 in hyaluronan synthase 2 is essential for hyaluronan synthesis

Biochemical and Biophysical Research Communications, 2020
Hyaluronan synthase 2 (HAS2) is an integral membrane protein composed of multi-membrane-spanning regions and a large intracellular loop (HAS2-loop). We previously examined the effect of phorbol 12-myristate 13-acetate (PMA) and/or 4-methylumbelliferone (4-MU) on the synthesis of hyaluronan (HA) in human skin fibroblasts and found that TPA and 4-MU have
Kosuke Kasai, Takashi Kobayashi, Tomisato Miura   +2 more
exaly   +3 more sources

Role of hyaluronan and hyaluronan synthase in endometrial cancer

Oncology Reports, 2005
The aim of this study was to determine if the immunohistochemical expression of hyaluronan synthase (HAS) and serum levels of hyaluronan correlate with the clinicopathological manifestations of endometrial carcinoma. Sera were obtained from 59 endometrial cancer patients and 22 post-menopausal healthy women.
Hiromitsu, Yabushita, Tameko, Kishida, Kanako, Fusano, Kouhei, Kanyama, Lisheng, Zhuo, Naoki, Itano, Koji, Kimata, Masayoshi, Noguchi   +7 more
openaire   +2 more sources

Hyaluronan and Hyaluronan Synthases: Potential Therapeutic Targets in Cancer

Current Drug Target -Cardiovascular & Hematological Disorders, 2005
Current models of oncogenesis describe cancer as a progression of genetic mutations in a tumor cell mass. However, tumors are more than a clonal expansion of malignant cells. Tumors are heterogeneous, with a complex 3D structure, analogous to organs comprised of different tissues.
Sophia, Adamia, Christopher A, Maxwell, Linda M, Pilarski   +2 more
openaire   +4 more sources

The Hyaluronan Synthase Catalyzes the Synthesis and Membrane Translocation of Hyaluronan

Journal of Molecular Biology, 2012
Hyaluronan (HA), an extracellular linear polysaccharide of alternating N-acetyl-glucosamine and glucuronic acid residues, is ubiquitously expressed in vertebrates, where it affects a broad spectrum of physiological processes, including cell adhesion, migration and differentiation. The HA polymer is synthesized on the cytosolic side of the cell membrane
Caitlin, Hubbard, Joshua T, McNamara, Caleigh, Azumaya, Mehul S, Patel, Jochen, Zimmer   +4 more
openaire   +2 more sources