Results 131 to 140 of about 87,553 (215)

Fibroblast growth factor-23 remodels vascular extracellular matrix via glycosaminoglycan induction: implications for calcification in chronic kidney disease

Renal Failure
Chronic kidney disease (CKD) leads to accumulation of uremic toxins, which contribute to cardiovascular disease (CVD) and mortality. Among these, fibroblast growth factor 23 (FGF-23), a bone-derived hormone, is associated with arterial stiffness ...
Christian Freise, Tia Jernej, Susanne Metzkow, Jörg Schnorr, Matthias Taupitz   +4 more
doaj   +1 more source

Regulation and roles of the hyaluronan system in mammalian reproduction [PDF]

, 2017
Afify, Afify, Ali A Fouladi-Nashta, Anderson, Assmann, Beck-Fruchter, Bergqvist, Berisha, Block, Bontekoe, Bourguignon, Boynukalin, Bravo, Brown, Chao, Chavoshinejad, Check, Chun, Contreras-Ruiz, Critser, Dahl, Dahl, Deng, Dietterich, El-Hayek, Evans, Fancsovits, Fataneh Ghafari, Fernandez, Geraldine M Hartshorne, Ghosh, Harkness, Hazlett, Homandberg, Illera, Kabir A Raheem, Kang, Kawakami, Kennel, Kershaw-Young, Kimura, Leppert, Loutradi, López, Maioral, Manicourt, Marei, Marek, Matou-Nasri, Misra, Mohey-Elsaeed, Nagyova, Nakagawa, Nakamura, Necas, Opiela, Ozbilgin, Perry, Prinosilova, Qian, Ranganathan, Rashki Ghaleno, Rayahin, Reddy, Richards, Rodriguez, Russell, Sakairi, Salustri, Sato, Saylan, Tammi, Tienthai, Tienthai, Ueno, Waleed F Marei, Weissmann, Yokoo, Zhou, Zhu   +79 more
core   +2 more sources

Bio-Functional Investigation and AI-Driven Target Interaction Prediction of Chrono Control Penta as a Plant Multifunctional Dermo Cosmetic Peptide

Cosmetics
Skin aging is influenced by both internal and external factors, resulting in wrinkles, decreased elasticity and irregular pigmentation. Hyaluronic acid (HA), a key component of the extracellular matrix, is essential for skin hydration and structural ...
Carmen Lammi, Raffaele Pugliese, Lorenza d’Adduzio, Umberto Maria Musazzi, Gilda Aiello, Melissa Fanzaga, Maria Silvia Musco, Carlotta Bollati   +7 more
doaj   +1 more source

The Modulation of Fibrosis in Vocal Fold Repair: A Study on c-Met Agonistic Antibodies and Hepatocyte Growth in Animal Studies

Medicina
Background and Objectives: Damage to the vocal folds frequently results in fibrosis, which can degrade vocal quality due to the buildup of collagen and modifications in the extracellular matrix (ECM). Conventional treatments have shown limited success in
Hyun-Il Shin, Hyunsu Choi, Jae-Kyun Jung, Choung-Soo Kim   +3 more
doaj   +1 more source

Biglycan : a multivalent proteoglycan providing structure and signals [PDF]

, 2013
Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule.
Năstase, Mădălina-Viviana, Schäfer, Liliana, Young, Marian F.   +2 more
core  

Functional analysis of human hyaluronan synthase 3 splicing variant 2

, 2010
Hyaluronan is a large glycosaminoglycan mainly presented in the extracellular matrix as well as in the intracellular compartment. Hyaluronan is synthesized by three hyaluronan synthase isoforms, namely HAS1, HAS2 and HAS3. HAS3v2 is a smaller splicing variant of HAS3 with 281 AA in length.
openaire   +2 more sources

Investigating the antioxidant and anti-inflammatory potential of Nypa fruticans: a multifaceted approach to skin protection and aging

Applied Biological Chemistry
Reactive oxygen species (ROS) produced in the mitochondria of skin cells play a significant role in the degradation of the extracellular matrix and induction of inflammatory responses, both of which are major contributors to skin aging. Antioxidants that
Seul Ki Kim, Sang-Back Kim, Seul Bi Lee, Kang sub Kim, So-Ri Son, En Jin Choi, Byung Chul Park, Eunyoung Hong, You Ah Kim, Byoung Seok Moon, Sullim Lee   +10 more
doaj   +1 more source

4-Methylumbelliferone inhibits ovarian cancer growth by suppressing thymidine phosphorylase expression [PDF]

, 2014

core   +1 more source

Inhibition of hyaluronan export reduces collagen degradation in interleukin-1 treated cartilage [PDF]

, 2008

core   +1 more source

Correction: Li et al. Genetic Deficiency of Hyaluronan Synthase 2 in the Developing Limb Mesenchyme Impairs Postnatal Synovial Joint Formation. Biomedicines 2025, 13, 1324. [PDF]

Biomedicines
Li Y, Tress A, Maye P, Edwards K, Findletar A, Dyment NA, Yamaguchi Y, Rowe DW, Le-Chan G, Chan SSK, Lo KW.   +10 more
europepmc   +1 more source