Results 81 to 90 of about 10,002 (164)

Doxycycline inhibits inflammation-induced lymphangiogenesis in mouse cornea by multiple mechanisms.

PLoS ONE, 2014
Lymphangiogenesis is significantly involved in the pathogenesis of diseases, including graft rejection, cancer metastasis and various inflammatory conditions.
Longhui Han, Wenru Su, Jingwen Huang, Jingwen Zhou, Sujuan Qiu, Dan Liang   +5 more
doaj   +1 more source

Taurine and Polyphenol Complex Repaired Epidermal Keratinocyte Wounds by Regulating IL8 and TIMP2 Expression

Current Issues in Molecular Biology
The healing process after acne lesion extraction provides a miniature model to study skin wound repair mechanisms. In this study, we aimed to identify solutions for acne scars that frequently occur on our faces.
Sooyeon Lee, Jae Young Shin, Oh Sun Kwon, Seung-Hyun Jun, Nae-Gyu Kang   +4 more
doaj   +1 more source

Multifunctional Dermatological Effects of Whole-Plant Bassia scoparia Extract: Skin Repair and Protection

Current Issues in Molecular Biology
Bassia scoparia (Syn. Kochia scoparia (L.) Schrad.) is a medicinal plant whose fruit, Kochiae Fructus, has been extensively studied for its dermatological applications. This study focused on extracts from the whole plant B.
Seogyun Jeong, Hye-Been Kim, Dong-Geol Lee, Eunjin Park, Seoyeon Kyung, Seunghyun Kang, Dayeon Roo, Sang Hyun Moh, Sung Joo Jang, Jihyeon Jang, HyungWoo Jo, Sanghun Lee   +11 more
doaj   +1 more source

Cell protrusions induced by hyaluronan synthase 3 (HAS3) resemble mesothelial microvilli and share cytoskeletal features of filopodia

Experimental Cell Research, 2015
Previous studies have shown that overexpression of enzymatically active GFP-HAS induces the growth of long, slender protrusions that share many features of both filopodia and microvilli. These protrusions are dependent on continuing hyaluronan synthesis, and disrupt upon digestion of hyaluronan by hyaluronidase. However, complete understanding of their
Koistinen, Ville, Kärnä, Riikka, Koistinen, Arto, Arjonen, Antti, Tammi, Markku, Rilla, Kirsi   +5 more
openaire   +4 more sources

LL-37 alone and in combination with IL17A enhances proinflammatory cytokine expression in parallel with hyaluronan metabolism in human synovial sarcoma cell line SW982-A step toward understanding the development of inflammatory arthritis.

PLoS ONE, 2019
LL-37 is the only human cathelicidin-family host defense peptide and has been reported to interact with invading pathogens causing inflammation at various body sites.
Chakkrapong Kuensaen, Siriwadee Chomdej, Patiwat Kongdang, Nutnicha Sirikaew, Rungnaree Jaitham, Supitcha Thonghoi, Siriwan Ongchai   +6 more
doaj   +1 more source

Leaves Extract Alleviates UVB-Induced HaCaT Cells Through Suppressing Mitogen-Activated Protein Kinases Activation

Natural Product Communications
Objectives Andrographis paniculata leaves have been widely used in traditional medicine due to their rich content of phenolic compounds. We sought to figure out the skin beneficial effects of Andrographis paniculata leaves extract. Methods In this study,
Al Borhan Bayazid, Ue Kyoung Hwang, Young Ah Jang, Yeong Hwan Jeong, Yu Chang Jo, Beong Ou Lim   +5 more
doaj   +1 more source

Sesamol regulates AQP3 and HAS2 via MAPK signaling for skin barrier protection an in vitro and molecular docking study

Scientific Reports
The integrity of the skin barrier is crucial for reducing the risk and managing chronic skin conditions such as photoaging, eczema, and atopic dermatitis.
Qiwen Zheng, So-Jeong Kim, Yong-Min Kim, Tae-Hoo Yi   +3 more
doaj   +1 more source

Development of a highly effective anti-aging and soothing recombinant Col III

Discover Applied Sciences
Collagen provides essential structural support to tissues and the extracellular matrix while participating in various biological processes, making it valuable in biomedicine, tissue engineering, and cosmetics.
Yuefeng Wang, Jing Zhang, Guoxia Xu, Ruiyan Wang, Wei Zhou   +4 more
doaj   +1 more source

Fibroblast growth factor-23 remodels vascular extracellular matrix via glycosaminoglycan induction: implications for calcification in chronic kidney disease

Renal Failure
Chronic kidney disease (CKD) leads to accumulation of uremic toxins, which contribute to cardiovascular disease (CVD) and mortality. Among these, fibroblast growth factor 23 (FGF-23), a bone-derived hormone, is associated with arterial stiffness ...
Christian Freise, Tia Jernej, Susanne Metzkow, Jörg Schnorr, Matthias Taupitz   +4 more
doaj   +1 more source

Bio-Functional Investigation and AI-Driven Target Interaction Prediction of Chrono Control Penta as a Plant Multifunctional Dermo Cosmetic Peptide

Cosmetics
Skin aging is influenced by both internal and external factors, resulting in wrinkles, decreased elasticity and irregular pigmentation. Hyaluronic acid (HA), a key component of the extracellular matrix, is essential for skin hydration and structural ...
Carmen Lammi, Raffaele Pugliese, Lorenza d’Adduzio, Umberto Maria Musazzi, Gilda Aiello, Melissa Fanzaga, Maria Silvia Musco, Carlotta Bollati   +7 more
doaj   +1 more source