Results 31 to 40 of about 67,369 (315)

Innovative insights on cleavage and hydrolysis mechanisms of hyaluronic acid: Opportunities and challenges in the preparation and application of hyaluronic acid and hyaluronidases

Carbohydrate Polymer Technologies and Applications
Hyaluronidase is used extensively across various domains, with food industry, healthcare, and surgical applications. Hyaluronidase produces low molecular weight hyaluronate through three mechanisms, substrate cleavage and two different hydrolysis ...
Panhong Yuan, Helin Li, Linjiang Zhu, Zonghui Song, Zhengsheng Pan, Xiaolong Chen   +5 more
doaj   +1 more source

Effects of Hyaluronidase during In Vitro Maturation on Maturation and Developmental Competence in Porcine Oocytes

Journal of Animal Reproduction and Biotechnology, 2019
The aim of this study was to investigate effects of hyaluronidase during IVM on oocyte maturation, oxidative stress status, expression of cumulus expansion-related (PTX, pentraxin; GJA1, gap junction protein alpha 1; PTGS2, prostaglandin-endoperoxide ...
Ye-Eun Jeon, Yong Hwangbo, Hee-Tae Cheong, Choon-Keun Park   +3 more
doaj   +1 more source

Biochemical Isolation and Characterization of Hyaluronidase Enzyme from Venom of Egyptian Honey Bee Apis Mellifera Lamarckii

Journal of Apicultural Science, 2020
The hyaluronidase enzyme has been used in many such fields of medicine as ophthalmology, orthopaedia, internal medicine, gynecology, surgery, oncology and dermatology.
Abdel-Monsef Mohammed M., Zidan Hind A., Darwish Doaa A., Masoud Hassan M., Helmy Mohamed S., Ibrahim Mahmoud A.   +5 more
doaj   +1 more source

Genotypic and Phenotypic Assessment of Hyaluronidase among Type Strains of a Select Group of Staphylococcal Species

International Journal of Microbiology, 2009
Hyaluronidases degrade hyaluronic acid, a major polysaccharide of the extracellular matrix of tissues, and are considered important for virulence in a number of Gram-positive and -negative bacteria.
Mark E. Hart, Morgan J. Hart, Anna J. Roop   +2 more
doaj   +1 more source

Appearance of fibronectin during the differentiation of cartilage, bone, and bone marrow. [PDF]

, 1981
Fibronectin has been localized by indirect immunofluorescence during the various phases of endochondral bone formation in response to subcutaneously implanted demineralized bone matrix.
Reddi, AH, Weiss, RE
core   +1 more source

Inhibition of Tityus serrulatus venom hyaluronidase affects venom biodistribution.

PLoS Neglected Tropical Diseases, 2019
BackgroundThe hyaluronidase enzyme is generally known as a spreading factor in animal venoms. Although its activity has been demonstrated in several organisms, a deeper knowledge about hyaluronidase and the venom spreading process from the bite/sting ...
Bárbara Bruna Ribeiro de Oliveira-Mendes, Sued Eustáquio Mendes Miranda, Douglas Ferreira Sales-Medina, Bárbara de Freitas Magalhães, Yan Kalapothakis, Renan Pedra de Souza, Valbert Nascimento Cardoso, André Luís Branco de Barros, Clara Guerra-Duarte, Evanguedes Kalapothakis, Carolina Campolina Rebello Horta   +10 more
doaj   +1 more source

Tumescent Injections in Subcutaneous Pig Tissue Disperse Fluids Volumetrically and Maintain Elevated Local Concentrations of Additives for Several Hours, Suggesting a Treatment for Drug Resistant Wounds. [PDF]

, 2020
PurposeBolus injection of fluid into subcutaneous tissue results in accumulation of fluid at the injection site. The fluid does not form a pool. Rather, the injection pressure forces the interstitial matrix to expand to accommodate the excess fluid in ...
Dunn, James CY, Huynh, Nhan, Koulakis, John P, Putterman, Seth, Rouch, Joshua, Wu, Holden H   +5 more
core   +2 more sources

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

Enhancing In Vivo Electroporation Efficiency through Hyaluronidase: Insights into Plasmid Distribution and Optimization Strategies

Pharmaceutics
Electroporation (EP) stands out as a promising non-viral plasmid delivery strategy, although achieving optimal transfection efficiency in vivo remains a challenge.
Debnath Maji, Verónica Miguela, Andrew D. Cameron, Delcora A. Campbell, Linda Sasset, Xin Yao, Andy T. Thompson, Carleigh Sussman, David Yang, Robert Miller, Marek M. Drozdz, Rachel A. Liberatore   +11 more
doaj   +1 more source

Cloning and Characterization of Phospholipases A2 and Hyaluronidase Genes from the Venom of the Honeybee Apis mellifera carnica (Hymenoptera: Apidae)

Sociobiology, 2014
Bee venom contains the allergic enzymes phospholipases A2 (PLA2) and hyaluronidase. These enzymes have been extensively studied as therapeutic modalities because of their proven effects in pharmaceutical and clinical applications.
Junfang Lin
doaj   +1 more source