Results 91 to 100 of about 1,279,921 (275)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Pectin of Olecranon Honey Peach Effects on Intestinal Health and the Mechanisms Involved in Hybrid Grouper (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀)

Fishes
Water-soluble pectin (WSP) is a soluble dietary fiber with a high esterification degree and certain viscosity and emulsifying properties. It has diverse bioactivities—including antioxidant, anticancer, and anti-inflammatory properties.
Jinhui Wu, Xiaoxiao Zhang, Qinguo Song, Feifei Huang, Tinghua Li, Zhendong Qin, Li Lin, Fei Shi, Huifan Liu, Cuiyun Zou   +9 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Advances in grouper aquaculture

, 2004
Aquaculture of high-value finfish species, such as groupers, is an industry of increasing importance throughout the Asia-Pacific. This book looks at larval rearing to improve growth and survival of groupers during the hatchery phase; diet development to ...

core   +2 more sources

SUSTAINABILITY STRATEGY OF MARINE CULTURE BUSINESS IN KEPULAUAN SERIBU

Russian Journal of Agricultural and Socio-Economic Sciences, 2020
Marine culture business is an alternative profession that has a positive impact on Kepulauan Seribu society. One of the commodities being developed is hybrid grouper Epinephelus sp.
Nugrahadi H.A., Zulbainarni N., Adrianto L.   +2 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

A comparative analysis of growth and nutritional quality of the hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂) in a simulated pond system and a recirculating aquaculture system

Frontiers in Marine Science
Groupers, as a popular economic fish species, are now more frequently cultured in land-based facilities, however, traditional pond-farming methods are plagued by frequent disease outbreaks, unstable economic benefits, and environmental pollution.
Yingsha Qu, Yingsha Qu, Yingsha Qu, Zhendong Yin, Zhendong Yin, Xiangyu Fan, Xiangyu Fan, Haiyan Hu, Hongwu Cui, Hongwu Cui, Zhengguo Cui, Zhengguo Cui, Keming Qu, Keming Qu, Hao Li, Hao Li   +15 more
doaj   +1 more source

Analysis of hybrid Nd:Yag laser-MAG arc welding processes. [PDF]

, 2011
In the hybrid laser-arc welding process, a laser beam and an electric arc are coupled in order to combine the advantages of both processes: high welding speed, low thermal load and high depth penetration thanks to the laser; less demanding on joint ...
F. Coste, E. Le Guen, P. Le Masson, COSTE, Frédéric, LE MASSON, Philippe, M. Carin, LE GUEN, Emilie, FABBRO, Rémy, CARIN, Muriel, R. Fabbro   +9 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source