Results 81 to 90 of about 5,314 (250)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

SUSTAINABILITY STRATEGY OF MARINE CULTURE BUSINESS IN KEPULAUAN SERIBU

Russian Journal of Agricultural and Socio-Economic Sciences, 2020
Marine culture business is an alternative profession that has a positive impact on Kepulauan Seribu society. One of the commodities being developed is hybrid grouper Epinephelus sp.
Nugrahadi H.A., Zulbainarni N., Adrianto L.   +2 more
doaj   +1 more source

Potential of grouper hybrid (Epinephelus fuscoguttatus x E. polyphekadion) for aquaculture [PDF]

Naga, 1999
The marine grouper species are considered high value food fish in several countries. However, controlled breeding and hatchery production of grouper fingerlings for commercial farming is still in its infancy. Investigations on the growth performance of the brown marbled grouper Epinephelus fuscoguttatus (Forskal), camouflage grouper E.
James, C.M., Al-Thobaiti, S.A., Rasem, B.M., Carlos, M.H.   +3 more
openaire   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A comparative analysis of growth and nutritional quality of the hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂) in a simulated pond system and a recirculating aquaculture system

Frontiers in Marine Science
Groupers, as a popular economic fish species, are now more frequently cultured in land-based facilities, however, traditional pond-farming methods are plagued by frequent disease outbreaks, unstable economic benefits, and environmental pollution.
Yingsha Qu, Yingsha Qu, Yingsha Qu, Zhendong Yin, Zhendong Yin, Xiangyu Fan, Xiangyu Fan, Haiyan Hu, Hongwu Cui, Hongwu Cui, Zhengguo Cui, Zhengguo Cui, Keming Qu, Keming Qu, Hao Li, Hao Li   +15 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

The complete mitochondrial genome of the hybrid grouper Epinephelus lanceolatus (♀) × E. akaara (♂)

Mitochondrial DNA. Part B. Resources, 2018
This study determined the complete mitochondrial genome of the hybrid grouper Epinephelus lanceolatus ♀ × E. akaara ♂. The complete mitochondrial genome is 16,743 bp long and includes 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA ...
Jae Hoon Kim, Jong Yeon Park, Choong Hwan Noh, Min Joo Kang, Thai Quoc Truong, In-Chul Bang   +5 more
doaj   +1 more source