Results 61 to 70 of about 8,842 (298)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Nursery Management of Cantang Grouper (Epinephelus fuscoguttatus-lanceolatus) at Convrete Pond in Balai Perikanan Budidaya Air Payau (BPBAP), Situbondo – East Java.

Journal of Marine and Coastal Science, 2021
Cantang groupers is an Indonesian fishery commodity is superior and has a high economic value. Cantang groupers (Epinephelus fuscoguttatus-lanceolatus) is an engineered hybrid seeds of cross-breeding between male parent fish giant grouper (Epinephelus ...
Steffani Lutfi Yuni firdausi, A Shofy Mubarak   +1 more
doaj   +1 more source

Effects of Low Salinity on Growth, Survival, and Stress Response in the Longtooth Grouper, Epinephelus bruneus, and E. bruneus × E. lanceolatus Hybrid Grouper [PDF]

Israeli Journal of Aquaculture - Bamidgeh, 2018
This study investigated the effects of low salinity on growth, survival, and stress response in longtooth grouper, Epinephelus bruneus, and the hybrid grouper resulting from crossing E. bruneus females and E. lanceolatus males.
Park, Y. J., Yoon, N.J., Kyu, L.H.
openaire   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

EGGS PRODUCTION OF GROUPER HYBRID FOR SUPPORTING HATCHERY BUSINESS

Jurnal Ilmu dan Teknologi Kelautan Tropis, 2018
The grouper hatchery now has been widely developed, usually purchased eggs from the business that produces hybrid grouper eggs   in accordance with the amount as needed. Eggs grouper that is currently in demand are eggs grouper cantang that is a cross-breed between female tiger grouper (Epinephelus fuscoguttatus) and male giant grouper (Epinephelus ...
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

BEBERAPA MACAM CACAT TUBUH YANG TERJADI PADA BENIH IKAN KERAPU CANTANG HASIL HATCHERY

JFMR-Journal of Fisheries and Marine Research, 2020
Cantang grouper is a hybrid between female tiger grouper (Epinephelus fuscoguttatus) and male giant grouper (Epinephelus lanceolatus) cantang grouper is currently in big demand for aquaculture because it has fast growth.
Suko Ismi
doaj   +1 more source

Formation of diploid and triploid hybrid groupers (hybridization of Epinephelus coioides ♀ × Epinephelus lanceolatus ♂) and their 5S gene analysis [PDF]

BMC Genetics, 2016
Interspecies hybridization is widely used to achieve heterosis or hybrid vigor, which has been observed and harnessed by breeders for centuries. Natural allopolyploid hybrids generally exhibit more superior heterosis than both the diploid progenies and their parental species.
Huang, Wen, Qin, Qinbo, Yang, Huirong, Li, Shuisheng, Hu, Chaoqun, Wang, Yude, Zhang, Yong, Liu, Shaojun, Lin, Haoran   +8 more
openaire   +2 more sources