Results 51 to 60 of about 8,842 (298)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The complete mitochondrial genome of the hybrid offspring Epinephelus awoara♀ × Epinephelus tukula♂

Mitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome of hybrid grouper from Epinephelus awoara (♀) ×E. tukula (♂) was obtained by PCR amplification. The circular genome was 16,801 bp in length, consisting of 13 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA ...
Ziqi Li, Yongsheng Tian, Zhentong Li, Shuai Chen, Linna Wang, Linlin Li, Jingjing Zhang, Yuping Wu, Zunfang Pang, Wenhui Ma, Jieming Zhai   +10 more
doaj   +1 more source

Screening and Characterization of Potential Antioxidant Probiotics Isolated from the Gut of Hybrid Grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂)

Frontiers in Marine Science, 2022
Some symbiotic probiotics have antioxidant activities and could improve the antioxidant capacity of the host. There is still no report on the screening of host-derived antioxidant probiotics for grouper farming.
Qian Zhang, Qian Zhang, Yan Cai, Yan Cai, Zihan Chen, Zihan Chen, Huizhong Shi, Huizhong Shi, Yongcan Zhou, Yongcan Zhou, Yang Yang, Yang Yang, Rui Tu, Rui Tu, Guisen Chen, Guisen Chen, Shifeng Wang, Shifeng Wang   +17 more
doaj   +1 more source

Effect of Salinities on Gastric Emptying and Nutrient Absorption of Tiger Grouper × Giant Grouper (Epinephelus fuscoguttatus × E. lanceolatus) Hybrid

Sains Malaysiana, 2018
The effects of salinity on the gastric emptying time (GET) and absorption of nutrient along the alimentary tract of tiger grouper (TG) × giant grouper (GG) (Epinephelus fuscoguttatus × E. lanceolatus) hybrid were studied. Juveniles TG×GG hybrid grouper (10.0 ± 0.5 cm total length; 50.5 ± 2.0 g) were reared in different salinities (10, 15, 20, 25 and 30
Noorashikin Md Noor, Simon Kumar Das, Zaidi Che Cob, Mazlan Abd. Ghaffar   +3 more
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Financial analysis business of cantang (Epinephelus fuscoguttatus × E. lanceolatus) and cantik (E. fuscoguttatus × E. polyphekadion) hybrid groupers in hatcheries

Aquaculture Reports
Management evaluation is essential to optimize finances by increasing egg production, survival rates, larval rearing, and nursery growth. Research aims to analyze production and financial performance in sustainable practices for producing hybrid grouper ...
Belinda Astari, Irzal Effendi, Tatag Budiardi, Yani Hadiroseyani, Iis Diatin, Suko Ismi   +5 more
doaj   +1 more source

Effects of Lower Fishmeal With Hydrolyzed Fish Protein Powder on the Growth Performance and Intestinal Development of Juvenile Pearl Gentian Grouper (Epinephelus fuscoguttatus ♀ and Epinephelus lanceolatus ♂)

Frontiers in Marine Science, 2022
The effect of hydrolyzed fish protein powder (HFP) on the growth, intestinal development, gene mRNA expression, and enzyme activity in the intestine and liver of juvenile hybrid grouper (Epinephelus fuscoguttatus ♀ and Epinephelus lanceolatus ♂) was ...
Vivian Hlordzi, Vivian Hlordzi, Junqing Wang, Tianbi Li, Zhiying Cui, Beiping Tan, Beiping Tan, Hongyu Liu, Hongyu Liu, Qihui Yang, Qihui Yang, Xiaohui Dong, Xiaohui Dong, Shuang Zhang, Shuang Zhang, Shuyan Chi, Shuyan Chi   +16 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Compound acidifier promoted the growth of hybrid grouper (♀Epinephelus fuscoguttatus × ♂Epinephelus lanceolatu) after high replacement of fish meal with cotton protein concentrate (CPC), improved stomach formation and digestibility, immune potency

Aquaculture Reports, 2023
Hybrid grouper (♀Epinephelus fuscoguttatus × ♂Epinephelus lanceolatu) is a popular aquaculture species in recent years. The latest research has found that cottonseed protein concentrate (CPC) has been found to be an effective alternative to fishmeal in ...
Jiacheng Zhang, Shuyan Chi, Beiping Tan, Xiaohui Dong, Shuang Zhang, Weixing Liang, Wenhao Gao, Chunyan Liao, Hongjin Deng   +8 more
doaj   +1 more source