Results 261 to 270 of about 88,475 (282)
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Macromolecule‐to‐Amphiphile Conversion Process of a Polyoxometalate–Polymer Hybrid and Assembled Hybrid Vesicles

Chemistry – A European Journal, 2012
AbstractWe report our findings on the macromolecule‐to‐amphiphile conversion process of a polyoxometalate–polymer hybrid and the assembled hybrid vesicles formed by aggregation of the hybrid amphiphile. The polyoxometalate–polymer hybrid is composed of a polyoxometalate (POM) cluster, which is covered by five tetrabutylammonium (Bu4N+) countercations ...
Yu, Xiao   +5 more
openaire   +2 more sources

Hybrid Nanospheres and Vesicles Based on Pectin as Drug Carriers

Langmuir, 2009
A novel strategy was developed to prepare nanospheres and vesicles as drug carriers. The drug-loaded pectin nanospheres and vesicles were fabricated in aqueous media containing Ca2+ and CO3(2-) ions under very mild conditions, which did not involve any surfactant.
Cui-Yun, Yu   +6 more
openaire   +2 more sources

Engineering Hybrid Extracellular Vesicles for Functional mRNA Delivery

Advanced Functional Materials
AbstractDespite the potential of extracellular vesicles (EVs) as nucleic acid delivery vectors, achieving efficient messenger RNA (mRNA) loading and cytoplasmic release of EV‐loaded mRNA cargo remains a critical challenge. Here, the properties of lipid nanoparticles (LNP) are explored to enhance mRNA loading and endosomal escape in human‐induced ...
Ana Filipa Louro   +6 more
openaire   +1 more source

Protease-responsive polymer vesicle by peptide-polymer hybrid

2016
Protease-sensitive polymer vesicles are a potential carriers for stimuli-responsive drug delivery. There are only few protease-sensitive polymer vesicles developed. This thesis aims to prepare protease-sensitive polymer vesicles for triggere-release. The factors that affect the cleavage-induced release have not been explored yet.
openaire   +2 more sources

HYBRID EXTRACELLULAR VESICLES, METHODS OF PREPARING HYBRID EXTRACELLULAR VESICLES, AND USES THEREOF

Encapsulating significant amounts of macromolecules into EVs is challenging, and no comprehensive method for achieving this has been established. Active loading techniques typically involve disrupting the vesicle bilayer to facilitate drug encapsulation, which is particularly important for incorporating drugs with relatively high molecular weights ...
Elita Montanari, Raffaella Daniele
openaire   +1 more source

RNA delivery by extracellular vesicles in mammalian cells and its applications

Nature Reviews Molecular Cell Biology, 2020
Killian P O'brien   +2 more
exaly  

Polymer–Lipid Hybrid Vesicles and Their Interaction with HepG2 Cells

Small, 2020
Edit Brodszkij   +2 more
exaly  

Extracellular vesicles: biology and emerging therapeutic opportunities

Nature Reviews Drug Discovery, 2013
Imre Mäger   +2 more
exaly  

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