Results 71 to 80 of about 41,031 (146)

Polymer Micelles vs Polymer-Lipid Hybrid Vesicles: A Comparison Using RAW 264.7 Cells. [PDF]

open access: yesBiomacromolecules, 2022
Ade C   +6 more
europepmc   +1 more source

Smart Vesicle Therapeutics: Engineering Precision at the Nanoscale

open access: yesPharmaceutics
Smart vesicle therapeutics represent a transformative frontier in nanomedicine, offering precise, biocompatible, and adaptable platforms for drug delivery and theranostic applications. This review explores recent advances in the design and engineering of
Luciano A. Benedini, Paula V. Messina
doaj   +1 more source

Bone‐targeted hybrid extracellular vesicles for alveolar bone regeneration

open access: yesInterdisciplinary Medicine
Prolonged tooth loss causes a blade‐like narrowing of the alveolar bone, severely impairing chewing function and aesthetics and complicating subsequent orthodontic or restorative treatments.
Anqi Liu   +8 more
doaj   +1 more source

Hybrid Extracellular Vesicles for Efficient Loading and Functional Delivery of mRNA

open access: yesJournal of Extracellular Vesicles
ABSTRACT Extracellular vesicles (EVs) are an attractive delivery vehicle with biological activity, intrinsic homing, low immunogenicity, and engineerability; however, challenges remain regarding loading and functional delivery of mRNA.
Xiaoqin Wang   +8 more
openaire   +2 more sources

Dual-targeted hybrid nanovesicles coordinated bone-muscle regeneration via regulating the DUSP4/p38 MAPK pathway to reverse osteosarcopenia

open access: yesJournal of Nanobiotechnology
Osteosarcopenia (OSP), a degenerative syndrome characterized by concurrent osteoporosis and sarcopenia, exhibits persistently high global prevalence due to aging and disuse, yet lacks targeted therapies.
Benchi Che   +11 more
doaj   +1 more source

Gene Therapy for Inflammatory Cascade in Intrauterine Injury with Engineered Extracellular Vesicles Hybrid Snail Mucus‐enhanced Adhesive Hydrogels

open access: yesAdvanced Science
Early hyper‐inflammation caused by intrauterine injury triggered subsequent intrauterine adhesion (IUA). STAT1‐mediated M1 macrophages are confirmed to secrete pro‐inflammatory cytokines to accelerate inflammatory cascade and IUA formation by multi‐omics
Xiaotong Peng   +11 more
doaj   +1 more source

Hybrid Joint Fluid Extracellular Vesicles Drive Metabolic Damage Impairing Chondrogenesis

open access: yesInternational Dental Journal
Aim or purpose: Elucidate the role of joint fluid extracellular vesicles (EVs) in regulating the metabolic homeostasis of degenerative cartilage and uncover the mechanisms behind the limited chondrocyte regenerative capacity in temporomandibular joint ...
Ting Xiang, Xiaoxing Kou
doaj   +1 more source

Biosynthetic OMVs with endogenous GM-CSF loading for ultrasound-triggered in situ cancer vaccination

open access: yesJournal of Nanobiotechnology
Impaired dendritic cell (DC) recruitment, maturation, and antigen presentation within the immunosuppressive tumor microenvironment (TME) critically limit the efficacy of cancer immunotherapies. Strategies attempt to restore DC function using systemically
Rui Zhang   +13 more
doaj   +1 more source

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