Results 81 to 90 of about 2,551,139 (304)

From Individual to Stand Performance in Hybrids: Challenging the Optimal Parental Genetic Distance

Evolutionary Applications
Hybridization, the interbreeding of distinct genotypes, drives evolutionary processes like speciation and adaptation, potentially via phenotypic transgression, where hybrids exhibit novel traits.
Catharina Y. Utami, Cyrille Violle, Denis Vile, Lisa Perrier, François Vasseur   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Cross-species bacterial artificial chromosome (BAC) library screening via overgo-based hybridization and BAC-contig mapping of a yield enhancement quantitative trait locus (QTL) yld1.1 in the Malaysian wild rice Oryza rufipogon [PDF]

, 2005
The construction of BAC-contig physical maps is an important step towards a partial or ultimate genome sequence analysis. Here, we describe our initial efforts to apply an overgo approach to screen a BAC library of the Malaysian wild rice species, Oryza ...
Ratnam, Wickneswari, Nadarajah, Kalaivani, Romanov, Michael N, Song, Beng-Kah   +3 more
core  

Instability of chromosome number and DNA methylation variation induced by hybridization and amphidiploid formation between Raphanus sativus L. and Brassica alboglabra Bailey

BMC Plant Biology, 2010
Background Distant hybridization can result genome duplication and allopolyploid formation which may play a significant role in the origin and evolution of many plant species.
Wang Yanjie, Wei Lihua, Chen Honggao, Li Xiangsong, Wang Bing, Guo Weiwei, Li Xuanli, Wu Jiangsheng, Long Hong   +8 more
doaj   +1 more source

Genetic diversity analysis of the invasive gall pest Leptocybe invasa (Hymenoptera: Apodemidae) from China.

PLoS ONE, 2021
Leptocybe invasa Fisher et LaSalle is a global invasive pest that seriously damages Eucalyptus plants. Studying the genetic diversity, genetic structure and introgression hybridization of L.
Xin Peng, Hantang Wang, Chunhui Guo, Ping Hu, Lei Xu, Jing Zhou, Zhirou Ding, Zhende Yang   +7 more
doaj   +1 more source

From hybrids to hermaphrodites in population genetics [PDF]

Genome Biology, 2013
A report on the 46th annual PopGroup conference, Glasgow, UK, December 18-21, 2012.
Verity, R, Marquardt, J, Hatlen, A, Zohren, J   +3 more
openaire   +3 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Phylogenomic analyses of all species of swordtail fishes (genus Xiphophorus) show that hybridization preceded speciation

Nature Communications
Hybridization has been recognized to play important roles in evolution, however studies of the genetic consequence are still lagging behind in vertebrates due to the lack of appropriate experimental systems.
Kang Du, Juliana Morena Bonita Ricci, Yuan Lu, Mateo Garcia-Olazabal, Ronald B. Walter, Wesley C. Warren, Tristram O. Dodge, Molly Schumer, Hyun Park, Axel Meyer, Manfred Schartl   +10 more
doaj   +1 more source

Hybrid Genetic Algorithms

, 2022
Hybrid optimization methods have known significant interest in recent years and are being growingly used to solve complex problems in science and engineering. For instance, the famous evolutionary Genetic Algorithm can integrate other techniques within its framework to produce a hybrid global algorithm that takes advantages of that combination and ...
openaire   +1 more source