Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Hybridization among three native North American Canis species in a region of natural sympatry. [PDF]
PLoS ONE, 2008 Population densities of many species throughout the world are changing due to direct persecution as well as anthropogenic habitat modification. These changes may induce or increase the frequency of hybridization among taxa.
Frank Hailer, Jennifer A Leonard
doaj +1 more source
Climatic niche and neutral genetic diversity of the six Iberian pine species: a retrospective and prospective view [PDF]
, 2010 Quaternary climatic fluctuations have left contrasting historical footprints on the neutral genetic diversity patterns of existing populations of different tree species.
Soto de Viana, Álvaro
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]
, 2001 Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian +3 more
core +2 more sources
PLoS ONE, 2015 Animal hybridization is well documented, but evolutionary outcomes and conservation priorities often differ for natural and anthropogenic hybrids. Among primates, an order with many endangered species, the two contexts can be hard to disentangle from one
Joanna Malukiewicz +8 more
doaj +1 more source
Hybridization event between wild boars and domestic pigs in Hungary
, 2020 The hybridization between wild boar and domestic pig has occurred since the first domestication event, and it still occurs until today both naturally or through human intervention.
Astuti, Putri Kusuma
core
Cross-species bacterial artificial chromosome (BAC) library screening via overgo-based hybridization and BAC-contig mapping of a yield enhancement quantitative trait locus (QTL) yld1.1 in the Malaysian wild rice Oryza rufipogon [PDF]
, 2005 The construction of BAC-contig physical maps is an important step towards a partial or ultimate genome sequence analysis. Here, we describe our initial efforts to apply an overgo approach to screen a BAC library of the Malaysian wild rice species, Oryza ...
Ratnam, Wickneswari +3 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A gyermekkori 1-es típusú diabétesz genetikai és humorális immunológiai hátterének vizsgálata = Genetic and humoral immunologic determinants of childhood-onset type 1 diabetes [PDF]
, 2007 Az OTKA pályázat munkatervében kitűzött célok megvalósultak. A program az elmúlt három év alatt országos diabetes genetikai projektté nőtte ki magát (HUN-T1D-GENES program; www.diabet.hu/ diabetesgenetics).
Hermann, Róbert, Soltész, Gyula
core +1 more source