Results 61 to 70 of about 3,679,444 (316)

From Individual to Stand Performance in Hybrids: Challenging the Optimal Parental Genetic Distance

Evolutionary Applications
Hybridization, the interbreeding of distinct genotypes, drives evolutionary processes like speciation and adaptation, potentially via phenotypic transgression, where hybrids exhibit novel traits.
Catharina Y. Utami, Cyrille Violle, Denis Vile, Lisa Perrier, François Vasseur   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The Research Advances in Distant Hybridization and Gynogenesis in Fish

Reviews in Aquaculture
Distant hybridization and gynogenesis are two prevalent breeding techniques for fishes. Drawing from the research achievements of our team and the existing literature, we summarize the reproductive traits and genetic features of fishes derived from ...
Qizhi Liu, Shi Wang, Chenchen Tang, Min Tao, Chun Zhang, Yi Zhou, Qinbo Qin, Kaikun Luo, Chang Wu, Fangzhou Hu, Yude Wang, Qingfeng Liu, Wuhui Li, Jing Wang, R. Zhao, Shaojun Liu   +15 more
semanticscholar   +1 more source

Genetic diversity analysis of the invasive gall pest Leptocybe invasa (Hymenoptera: Apodemidae) from China.

PLoS ONE, 2021
Leptocybe invasa Fisher et LaSalle is a global invasive pest that seriously damages Eucalyptus plants. Studying the genetic diversity, genetic structure and introgression hybridization of L.
Xin Peng, Hantang Wang, Chunhui Guo, Ping Hu, Lei Xu, Jing Zhou, Zhirou Ding, Zhende Yang   +7 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Does human-induced hybridization have long-term genetic effects? Empirical testing with domesticated, wild and hybridized fish populations

Evolutionary Applications, 2014
Current conservation practices exclude human‐generated hybridized populations from protection, as the genetic effects of hybridization in the wild have been observed to be long‐lasting based on neutral genetic markers and are considered potentially ...
A. Harbicht, C. Wilson, D. Fraser
semanticscholar   +1 more source

Instability of chromosome number and DNA methylation variation induced by hybridization and amphidiploid formation between Raphanus sativus L. and Brassica alboglabra Bailey

BMC Plant Biology, 2010
Background Distant hybridization can result genome duplication and allopolyploid formation which may play a significant role in the origin and evolution of many plant species.
Wang Yanjie, Wei Lihua, Chen Honggao, Li Xiangsong, Wang Bing, Guo Weiwei, Li Xuanli, Wu Jiangsheng, Long Hong   +8 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Hybridization and extinction

Evolutionary Applications, 2016
Hybridization may drive rare taxa to extinction through genetic swamping, where the rare form is replaced by hybrids, or by demographic swamping, where population growth rates are reduced due to the wasteful production of maladaptive hybrids. Conversely,
M. Todesco, M. A. Pascual, Gregory L. Owens, Katherine L. Ostevik, Brook T. Moyers, Sariel Hübner, Sylvia M. Heredia, M. Hahn, Céline Caseys, Dan G. Bock, L. Rieseberg   +10 more
semanticscholar   +1 more source

Use of Fluorescence In Situ Hybridization (FISH) in Diagnosis and Tailored Therapies in Solid Tumors

Molecules, 2020
Fluorescence in situ hybridization (FISH) is a standard technique used in routine diagnostics of genetic aberrations. Thanks to simple FISH procedure is possible to recognize tumor-specific abnormality. Its applications are limited to designed probe type.
Natalia Chrzanowska, J. Kowalewski, M. Lewandowska   +2 more
semanticscholar   +1 more source