Results 51 to 60 of about 2,551,139 (304)

Translocation (8;21) in acute nonlymphocytic leukemia delineated by chromosomal in situ suppression hybridization [PDF]

, 1991
In situ suppression hybridization with recombinant bacteriophage DNA libraries for chromosomes 8 and 21 was performed in two cases of acute nonlymphocytic leukemia, type FAB M2.
Cremer, Thomas, Becher, Reinhard, Qiu, Jing Ying, Smialek, Barbara, Popp, Susanne, Jauch, Anna   +5 more
core   +1 more source

Hybridization and patterns of adaptive genetic variation in tropical trees of the Bertholletia clade (Lecythidaceae) in French Guiana

, 2017
Hybridization and patterns of adaptive genetic variation in tropical trees of the Bertholletia clade (Lecythidaceae) in French Guiana.
Molino, Jean-François, Mariette, Stéphanie, Scotti-Saintagne, Caroline, El Mutjar, Veronica, Franc, Alain, Heuertz, Myriam, Budde, Katharina Birgit, Caron, Henri, Guichoux, Erwan, Sabatier, Daniel, Garnier‐géré, Pauline, Jehanne, Quentin   +11 more
core   +7 more sources

Bucking the trend in wolf-dog hybridization: first evidence from europe of hybridization between female dogs and male wolves. [PDF]

PLoS ONE, 2012
Studies on hybridization have proved critical for understanding key evolutionary processes such as speciation and adaptation. However, from the perspective of conservation, hybridization poses a concern, as it can threaten the integrity and fitness of ...
Maris Hindrikson, Peep Männil, Janis Ozolins, Andrzej Krzywinski, Urmas Saarma   +4 more
doaj   +1 more source

Interspecific Hybridization Is an Important Driving Force for Origin and Diversification of Asian Cultivated Rice Oryza sativa L.

Frontiers in Plant Science, 2022
As one of the most important crops, Asian cultivated rice has evolved into a complex group including several subgroups adapting various eco-climate-systems around the globe.
Jiawu Zhou, Ying Yang, Yonggang Lv, Qiuhong Pu, Jing Li, Yu Zhang, Xianneng Deng, Min Wang, Min Wang, Jie Wang, Jie Wang, Dayun Tao   +11 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Do the benefits of polyandry scale with outbreeding? [PDF]

, 2015
There have been many potential explanations put forward as to why polyandry often persists despite the multiple costs it can inflict on females. One such explanation is avoidance of costs associated with mating with genetically incompatible males ...
Burdfield-Steel, Emily Rose, Auty, Sam, Burdfield-Steel, Emily, Shuker, David M., Shuker, David Michael   +4 more
core   +1 more source

Cryptic diversity and rampant hybridization in annual gentians on the Qinghai-Tibet Plateau revealed by population genomic analysis

Plant Diversity
Understanding the evolutionary and ecological processes involved in population differentiation and speciation provides critical insights into biodiversity formation.
Peng-Cheng Fu, Qiao-Qiao Guo, Di Chang, Qing-Bo Gao, Shan-Shan Sun   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The effect of polyploidy and hybridization on the evolution of floral colour in Nicotiana (Solanaceae). [PDF]

, 2015
Speciation in angiosperms can be accompanied by changes in floral colour that may influence pollinator preference and reproductive isolation. This study investigates whether changes in floral colour can accompany polyploid and homoploid hybridization ...
Taylor, L, Arnold, Sarah E., Arnold, SE, Arnold, Sarah E. J., Chittka, Lars, Chittka, L, Kovařík, A, Le Comber, S., Knapp, S., Baldwin, Ian, Mhiri, C, Verity, Robert, Verity, R, Le Comber, SC, Taylor, Lin, Kelly, L., Le Comber, Steven C., Knapp, Sandra, Knapp, S, Leitch, A.R., Arnold, SEJ, Baldwin, I., Chase, M.W., Chittka, L., Leitch, AR, Leitch, Andrew R., Arnold, Sarah E.J., Mhiri, Corinne, McCarthy, E.W., Chase, Mark W., Kelly, LJ, Taylor, L., Arnold, S.E.J., Chase, M., Kovařík, Aleš, Kovařík, A., McCarthy, E., Leitch, A., Verity, R., McCarthy, Elizabeth W., Dodsworth, Steven, Kelly, L.J., Kelly, Laura J., Dodsworth, S., Mhiri, C., Dodsworth, S, Chase, MW, Arnold, S., Baldwin, I.T., Baldwin, Ian T., Le Comber, S.C., Baldwin, IT, McCarthy, EW   +52 more
core   +1 more source

The dynamics of hybrid metabolic-genetic oscillators

Chaos: An Interdisciplinary Journal of Nonlinear Science, 2013
The synthetic construction of intracellular circuits is frequently hindered by a poor knowledge of appropriate kinetics and precise rate parameters. Here, we use generalized modeling (GM) to study the dynamical behavior of topological models of a family of hybrid metabolic-genetic circuits known as “metabolators.” Under mild assumptions on the kinetics,
Reznik, Ed, Kaper, Tasso J., Segre, Daniel   +2 more
openaire   +4 more sources