Results 41 to 50 of about 1,066,085 (279)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Remote Toehold: A Mechanism for Flexible Control of DNA Hybridization Kinetics [PDF]

open access: yes, 2011
Hybridization of DNA strands can be used to build molecular devices, and control of the kinetics of DNA hybridization is a crucial element in the design and construction of functional and autonomous devices. Toehold-mediated strand displacement
Bath, Jonathan   +3 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Influence of Hybridization on the Properties of the Spinless Falicov-Kimball Model

open access: yes, 1998
Without a hybridization between the localized f- and the conduction (c-) electron states the spinless Falicov-Kimball model (FKM) is exactly solvable in the limit of high spatial dimension, as first shown by Brandt and Mielsch.
A. Georges   +28 more
core   +1 more source

The study of a combinative ability of winter wheat (review)

open access: yesЗерновое хозяйство России, 2018
The study of a combinative ability of winter wheat (review) The paper presents a survey of the researches carried out to study the combinational ability of wheat by both domestic and foreign scientists. K.M.
O. A. Nekrasova, E. I. Nekrasov
doaj   +1 more source

Hybrid economics, hybrid politics, hybrid wars: communication and signs of hybridity

open access: yes, 2020
The subject of the study is an essence and sources of the concept of hybrid war, signs of hybridity. Topicality. In recent years, the Russian Federation has been waging a hybrid war against Ukraine. The source of hybrid wars is hybrid politics and hybrid economics.
KLYMENKO, P.M., SHEVCHUK, V.I.
openaire   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Band-theoretical prediction of magnetic anisotropy in uranium monochalcogenides

open access: yes, 2000
Magnetic anisotropy of uranium monochalcogenides, US, USe and UTe, is studied by means of fully-relativistic spin-polarized band structure calculations within the local spin-density approximation.
B. Reihl   +22 more
core   +1 more source

Hybrid nanophotonics [PDF]

open access: yesUspekhi Fizicheskih Nauk, 2017
Abstract Advances in the field of plasmonics, i.e., nano-photonics exploiting the optical properties of metal nanostructures, paved the way for the development of ultrasensitive devices, including biological and various other sensors whose operation is based on the nanoscale localization of the electromagnetic field. However, the high
Lepeshov, SI   +3 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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