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Developments in biological standardization, 1995
Hybridoma stability issues include mutations, chromosome losses, and the potential effects of process variables on the yield, quality and homogeneity of the Monoclonal Antibody (MAb) product. MAb production by murine hybridomas is typically unstable in the early stages after fusion but repeated cloning normally produces stable clones.
F J, Castillo +7 more
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Hybridoma stability issues include mutations, chromosome losses, and the potential effects of process variables on the yield, quality and homogeneity of the Monoclonal Antibody (MAb) product. MAb production by murine hybridomas is typically unstable in the early stages after fusion but repeated cloning normally produces stable clones.
F J, Castillo +7 more
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Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes
Nature, 1989Yufang Shi, B. Sahai, D. Green
semanticscholar +1 more source
Antibody production by hybridomas.
JIM - Journal of Immunological Methods, 1980J. Goding
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Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas
Nature, 2002Alberto Martin +5 more
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Hybrid hybridomas and their use in immunohistochemistry
Nature, 1983C. Milstein, A. Cuello
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Polyspecificity of monoclonal lupus autoantibodies produced by human-human hybridomas.
New England Journal of Medicine, 1983Y. Shoenfeld +6 more
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