New Roads Leading to Old Destinations: Efflux Pumps as Targets to Reverse Multidrug Resistance in Bacteria [PDF]
Multidrug resistance (MDR) has appeared in response to selective pressures resulting from the incorrect use of antibiotics and other antimicrobials.
Amaral, Leonard +3 more
core +2 more sources
Hydantoin-Based Molecular Photoswitches
A new family of molecular photoswitches based on arylidenehydantoins is described together with their synthesis and photochemical and photophysical studies. A series of hydantoin derivatives have been prepared as single isomers using simple and versatile chemistry in good yields.
Martinez Lopez, David +7 more
openaire +3 more sources
Antinociceptive Effect of Hydantoin 3-Phenyl-5-(4-ethylphenyl)-imidazolidine-2,4-dione in Mice
Imidazolidine derivatives, or hydantoins, are synthetic compounds with different therapeutic applications. Many imidazolidine derivatives have psychopharmacological properties, such as phenytoin, famous for its anticonvulsant efficacy, but also effective
Ronaldo Bezerra de Queiroz +11 more
doaj +1 more source
On the genus Anchonus Schönherr in Florida (Coleoptera: Curculionidae) [PDF]
Four species of Anchonus Schonherr occur in Florida: A. flol'idanus Schwarz, A. dul'yi Blatchley, A. blatchleyi Sleeper, and A. suillus (Fabricius), which is recorded from Florida and the continental United States for the first time.
O'Brien, Charles W., Thomas, Michael C.
core
Structures of tribenzylmethanol and 1,2,3-triphenyl-2-propanol [PDF]
The tribenzylmethanol molecule, (PhCH2)3COH, has approximate threefold symmetry in the solid state. The hydroxyl H atom is disordered unequally over three orientations and is not involved in hydrogen bonding.
Ferguson, George +4 more
core +2 more sources
Electrospun biodegradable polymers loaded with bactericide agents [PDF]
Development of materials with an antimicrobial activity is fundamental for different sectors, including medicine and health care, water and air treatment, and food packaging.
Franco García, María Lourdes +3 more
core +2 more sources
Crucial Role of Oxidation for the Prebiotic Peptide Elongation Promoted by Carbonyl Sulfide
The prebiotic activation of amino acid (AA) into peptides via N‐carboxyanhydride (NCA), promoted by carbonyl sulfide (COS), cannot proceed without an oxidizing step (enabling better leaving groups than sulfur dianion). While being efficient even at mild pH the prebiotic scope of COS promoted activation of AA, it is however limited because side ...
Alexandre Desfoux +4 more
wiley +1 more source
3’-Methyl-4-thio-1H-tetrahydropyranspiro-5’-hydantoin platinum complex as a novel deoxyribonuclease I inhibitor [PDF]
Deoxyribonuclease I (DNase I) is one of the main nucleases involved in deoxyribonucleic acid (DNA) degradation during apoptosis. It catalyzes the hydrolytic cleavage of DNA, producing 5‘-oligonucleotides.
Ana Marković +5 more
doaj +3 more sources
Common Mitochondrial DNA Mutations Generated through DNA-Mediated Charge Transport [PDF]
Mutation sites that arise in human mitochondrial DNA as a result of oxidation by a rhodium photooxidant have been identified. HeLa cells were incubated with [Rh(phi)2bpy]Cl3 (phi is 9,10-phenanthrenequinone diimine), an intercalating photooxidant, to ...
Barton, Jacqueline K. +2 more
core +2 more sources
In the title molecule, C21H17N3O2, the five-membered ring is slightly ruffled and dihedral angles between the pendant six-membered rings and the central, five-membered ring vary between 50.78 (4) and 86.78 (10)°.
Abderrazzak El Moutaouakil Ala Allah +5 more
doaj +1 more source

