Results 81 to 90 of about 13,210 (268)

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

open access: yesAdvanced Functional Materials, Volume 36, Issue 28, 7 April 2026.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya   +14 more
wiley   +1 more source

Visible‐Light Mediated Functionalization in Phe‐Containing Peptides Upon a Debenzylative Amination Process

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.
Selective late‐stage modification of N‐terminal phenylalanine short peptides is achived by visible‐light initiated reaction with N‐iodoimides in a debenzylation–amination process. This metal‐free method permits the incorporation of N‐containing heterocycles into the α‐position of the peptide backbone.
Guillermo Morales‐Ortega   +4 more
wiley   +1 more source

Synthesis of Peptides, Peptide Nucleic Acid Components, and Other Biogenic Compounds From a Three‐Component Prebiotic Mixture

open access: yesChemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
High‐energy proton irradiation of a formamide–diaminomaleonitrile–glycine system in the presence of meteorites produces a broad spectrum of biogenic compounds, including nucleobases, nucleosides, peptides, and nucleobase–peptide conjugates, highlighting a chemically plausible prebiotic network.
Bruno Mattia Bizzarri   +6 more
wiley   +1 more source

Prevalence of Contact Sensitisation Among Patients With Atopic Dermatitis in Thailand: A 20‐Year Retrospective Study

open access: yes
Contact Dermatitis, EarlyView.
Silada Kanokrungsee   +6 more
wiley   +1 more source

Thermotolerant D‐Hydantoinases for Efficient and Stereoselective Intermediate Synthesis of (R)‐3‐Isobutylglutaric Acid Monoamide, a Key Intermediate in Pregabalin Production

open access: yesMicrobial Biotechnology, Volume 19, Issue 3, March 2026.
We engineered thermo‐alkali‐stable D‐hydantoinases via mutagenesis (M63A/F65H/C317T) to resolve Pregabalin's challenging chiral splitting, achieving ee value > 97% for key intermediate (R)‐3‐isobutylglutaric acid monoamide (R‐IBM) synthesis under extreme conditions (pH 10, 70°C–80°C).
Jiujiuzi Zhang   +5 more
wiley   +1 more source

Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019–2024

open access: yesContact Dermatitis, Volume 94, Issue 3, Page 272-285, March 2026.
Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez   +29 more
wiley   +1 more source

Antiproliferative and antimigratory effects of 3-(4-substituted benzyl)-5- isopropyl-5-phenylhydantoin derivatives in human breast cancer cells

open access: yesSaudi Pharmaceutical Journal, 2020
In this study, a series of synthesized 3-(4-substituted benzyl)-5-isopropyl-5-phenylhydantoin derivatives as a potential antiproliferative and antimigratory agents were investigated. The possible antitumor mechanisms of investigated hydantoin derivatives
Ana Obradović   +7 more
doaj   +1 more source

Tautomeric Equilibria Studies by Mass Spectrometry [PDF]

open access: yes, 2008
Tautomerism in organic chemistry has been extensively studied in condensed phase by spectrometric methods, mainly by IR and NMR techniques. Mass spectrometry studies start 40 years ago but just recently it has been recognized the importance of the mass ...
Eduardo A. Castro   +3 more
core   +1 more source

Highly Substituted 1,4‐Benzodiazepin‐2‐ones: A Rapid Modular Approach From Arynes and Unsymmetrical Imides

open access: yesChemistryEurope, Volume 4, Issue 2, February 2026.
In this work, 1,4‐benzodiazepine‐2‐ones are synthesized starting from Kobayashi‐type aryne precursors and amino acid‐derived, unsymmetrical imides. Operationally simple protocols to access both the starting materials and the potential active pharmaceutical ingredients are presented.
Jasper Mindner   +5 more
wiley   +1 more source

学会抄録 [PDF]

open access: yes, 2016
Mauve visualization of local collinear blocks identified among 14 haplotypes (15BACs) from Saccharum species and sorghum.
Anupma Sharma (257041)   +8 more
core   +6 more sources

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