Results 61 to 70 of about 13,210 (268)
Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance
Chemistry – A European Journal, EarlyView.This review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Luigi Dolcini +3 more
wiley +1 more source
Exploring hydantoin frameworks: synthetic approaches and therapeutic potential
Future Journal of Pharmaceutical SciencesBackground Since its first synthesis in the nineteenth century, hydantoin has emerged as a vital scaffold in drug development, especially for anticonvulsant, antimicrobial, antitumor, and anti-inflammatory agents.
Nirmala V. Shinde +6 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2018 A practical three-step protocol for the assembly of triazolobenzodiazepine-fused diketopiperazines and hydantoins has been developed. The synthesis of these tetracyclic ring systems was initiated by an Ugi reaction, which brought together all necessary ...
Robby Vroemans +7 more
doaj +1 more source
Inhibitor binding mode and allosteric regulation of Na+-glucose symporters. [PDF]
, 2018 Sodium-dependent glucose transporters (SGLTs) exploit sodium gradients to transport sugars across the plasma membrane. Due to their role in renal sugar reabsorption, SGLTs are targets for the treatment of type 2 diabetes.
Althoff, Thorsten +9 more
core +2 more sources
Química Nova, 2008 Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds.
Silvânia Maria de Oliveira +5 more
doaj +1 more source
The Pyroglutamate Hydantoin Rearrangement [PDF]
European Journal of Organic Chemistry, 2006 AbstractWhen a mixture of a pyroglutamate and an isocyanate in THF is treated with NaH, a ring transformation occurs leading to functionalised hydantoins. The novel reaction involves a ring‐closing ring‐opening sequence providing a new and straightforward access to an interesting class of heterocyclic compounds.
Nicolai Dieltiens +6 more
openaire +1 more source
Contact Dermatitis, EarlyView.ABSTRACT Formaldehyde and its releasers are common preservatives and potent sensitizers. This meta‐analysis aimed to estimate the prevalence of formaldehyde contact allergy and allergy to its five most common releasers among dermatitis patients. Two authors independently searched PubMed, Embase, and Web of Science from inception to 30th September 2025.
Kian Karimian +5 more
wiley +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
The FEBS Journal, EarlyView.ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Acta Crystallographica Section E: Crystallographic CommunicationsThe new phenytoin analogue 5,5-diphenyl-3-(2-propyn-1-yl)imidazolidine-2,4-dione, C18H14N2O2 (3), was obtained through an alkylation reaction with propargyl bromide via the phase-transfer catalysis method, and its structure was determined via single ...
Abderrazzak El Moutaouakil Ala Allah +5 more
doaj +1 more source
Journal of Saudi Chemical Society, 2023 Several DFT approaches with 6–311 + G(2df,2p) basis set at the B3LYP/6–31 + G(d,p) geometries were examined to calculate accurate adiabatic electron affinity (AEA) for some hydantoin derivatives.
Nuha Wazzan, Zaki Safi
doaj +1 more source