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Comparative Genomic and Transcriptomic Analysis Reveals Why Paenarthrobacter Strains Are Specialists in the Degradation of the Fungicide Iprodione. [PDF]
Michelioudakis V +7 more
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A promising dual catalytic "Isothiourea + X" platform: from classic ionic to radical transformations. [PDF]
Zhang B, Li Y, Ji Z, Wang J.
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Poly(methyl vinyl ether-<i>alt</i>-maleic anhydride) and Its Derivatives: From Polymer Synthesis to Advanced Biomedical Applications. [PDF]
Badía-Hernández PV +5 more
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Combinatorial chemistry of hydantoins
Access to combinatorial chemistry of hydantoins is provided by convenient and versatile methods for the solid phase synthesis of libraries of 3,5-, 1,3- and 1,3,5-substituted hydantoins. The preparation of trisubstituted hydantoins features a Mitsunobu reaction for introduction of the substituent on N-1.
Boeijen, A. +2 more
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A Sustainable, Semi‐Continuous Flow Synthesis of Hydantoins
Hydantoins are an important class of heterocycles with applications in pharmacy, agriculture, and as intermediates in organic synthesis. Traditional synthetic procedures to access hydantoins are target oriented with multiple synthetic steps, often use ...
Kerry Gilmore +2 more
exaly +2 more sources
Facile synthesis of hydantoins and thiohydantoins in aqueous solution
A series of hydantoins and thiohydantoins have been synthesized in water at room temperature from urea (or N-methylurea, or thiourea) and simple aldehydes (as glyoxal, and its simple derivatives) in the presence of phosphoric anhydride. The reaction time
Gabriele Micheletti +2 more
exaly +2 more sources
Microchemical tests for hydantoins and barbiturate-hydantoin mixtures
Microchemical Journal, 1972Abstract Substituted hydantoins, a number of which possess anticonvulsant activity and are prescribed alone or compounded with barbiturates, were observed to enter into a number of reactions commonly utilized to identify barbituric acid derivatives. The reactivity of the hydantoins with the Dille-Koppanyi and the Zwikker tests is sufficiently similar
Edward F. Rhodes, John I. Thornton
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SELENIUM-CONTAINING HYDANTOINS
Phosphorus and Sulfur and the Related Elements, 1988Abstract The influence of the exo-chalcogen atoms on the hydantoin skeleton of the complete series of molecules NH C(=X) NH C(=Y)CMe2 (X, Y = O, S, Se) has been studied from several points of view.
F. A. Devillanova +2 more
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Hydantoins as antitumor agents
Journal of Medicinal Chemistry, 1977A series of 27 hydantoins was prepared and tested as antitumor agents. These were variously substituted in the 5 position but with special emphasis on the substituents (chloro, acetyl, chloroacetyl, and methyl) in the 1 and/or 3 positions. The most active compound was 5,5-bis(4-chlorophenyl)-1,3-dichlorohydantoin with a T/C value of 190% against P-388 ...
T R, Rodgers +3 more
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