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Efficacy and Safety of Nifedipine Compared to Intravenous Hydralazine for Severe Hypertensive Disorders in Pregnancy: A Systematic Review and Meta-Analysis of Randmomized Controlled Trials. [PDF]

open access: yesMed Sci (Basel)
Govindasamy V   +16 more
europepmc   +1 more source

Antihypertensive therapy for pregnancy hypertension and implications for fetal and neonatal heart rate monitoring: A systematic review of randomized trials and observational studies. [PDF]

open access: yesActa Obstet Gynecol Scand
Ganeshamoorthy A   +9 more
europepmc   +1 more source
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Studies on hydralazine

European Journal of Clinical Pharmacology, 1976
The bioavailability of orally administered hydralazine was assessed in 4 healthy subjects after separate administration of a single oral or intravenous dose (0.3 mg-kg-1). Comparison of the areas under the serum concentration-time curves showed that 26-55% of the oral dose was available to the systemic circulation as unchanged drug.
openaire   +2 more sources

Pharmacokinetics of hydralazine, apparent hydralazine and hydralazine pyruvic acid hydrazone in humans.

Research communications in chemical pathology and pharmacology, 1980
Hydralazine is an antihypertensive vasodilator agent. Lack of specific assay techniques for its measurement have delayed elucidation of its pharmacokinetic profile. This study compares the plasma profiles of hydralazine, measured both by a specific and by a previously published nonspecific assay and of a major plasma metabolite, hydralazine pyruvic ...
A M, Shepherd   +4 more
openaire   +1 more source

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