Results 91 to 100 of about 15,167 (190)

Short-term hemodynamic effects of hydralazine in infants with complete atrioventricular canal defects.

open access: yes, 1984
We evaluated the acute hemodynamic responses to hydralazine during cardiac catheterization in eight infants (ages 1.0 to 5.5 months) with congestive heart failure due to complete atrioventricular canal defect.
R J Boucek   +4 more
core   +1 more source

Different phenotypes of the NAT2 gene influences hydralazine antihypertensive response in patients with resistant hypertension

open access: yes, 2014
Aim: Hydralazine, a vasodilator used in resistant hypertension (RH) treatment is metabolized by an acetylation reaction mediated by N-acetyltransferase 2, the activity of which depends on NAT2 polymorphisms.
Santos, Adalberto Rezende   +4 more
core   +1 more source

Haptenization as the missing link between vasculitis and myeloperoxidase

open access: yesThe Journal of Clinical Investigation
A wide variety of medications can induce adverse immune events and autoimmune responses such as vasculitis. Mechanistically, small molecule drugs known as haptens bind and modify endogenous proteins, triggering such immune reactions. In this issue of the
Laura Santambrogio
doaj   +1 more source

In Vivo and In Vitro Effects of Hydralazine on Cellular Growth, Differentiation and Chromatin Structure [PDF]

open access: yes, 1987
Hydralazine has been used medicinally as an antihypertensive since 1952. Within two years after its introduction to clinical medicine, an unusual set of symptoms was noted in a significant portion of patients.
Fasbender, Allen John
core   +1 more source

Hydralazine-Induced ANCA Vasculitis Presenting With Pericarditis: A Novel Case and Literature Review

open access: yesCase Reports in Cardiology
Hydralazine, a commonly used arterial vasodilator for managing congestive heart failure and hypertension, is known to be associated with drug-induced lupus and, less frequently, antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). Drug-
Ahmed Sami Hammami   +7 more
doaj   +1 more source

Comparison between Effects of Intravenous Labetalol and Hydralazine on Control of Hypertension and Maternal and Neonatal Outcomes in Severe Preeclamptic Patients: A Randomized Clinical Trial

open access: yes, 2013
Background and Objectives: Severe preeclampsia and eclampsia are responsible for 25% of maternal mortality, especially in developing countries. Considering the importance of this complication, the present study aimed to compare between effects of ...
Oghbaee N.   +3 more
core  

Effects of DNMT inhibitor hydralazine on LPS-induced rhabdomyolysis rats.

open access: yes, 2016
Effects of DNMT inhibitor hydralazine on LPS-induced rhabdomyolysis rats.
Chih-Chin Shih (283129)   +6 more
core   +1 more source

Diagnosis and Treatment of Eclampsia

open access: yesJournal of Cardiovascular Development and Disease
Hypertensive disorders of pregnancy affect approximately 5% to 10% of pregnant women. Eclampsia is a serious hypertensive disorder that is primarily characterized by the onset of grand mal seizure activity in the absence of other causative conditions ...
Vasiliki Katsi   +3 more
doaj   +1 more source

Hemodynamic effects of hydralazine in infants with a large ventricular septal defect.

open access: yes, 1982
To evaluate the effects of acute afterload reduction, hydralazine, 0.2 mg/kg, was administered at cardiac catheterization to seven infants who had a large ventricular septal defect (VSD). The infants were 2.5 - 11 months old (mean 5.1 months). Before and
R H Beekman, A P Rocchini, A Rosenthal
core   +1 more source

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