Results 91 to 100 of about 21,060 (203)
Epigenetic treatment of solid tumours. A review of clinical trials [PDF]
, 2015 Epigenetic treatment has been approved by regulatory agencies for haematological malignancies. The success observe in cutaneous lymphomas represents a proof of principle that similar results may be obtained in solid tumours. Several agents that interfere
CODACCI PISANELLI, Giovanni +2 more
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Treatment of Hypertension [PDF]
, 1965 Our ideas about the management of hypertension have changed considerably in recent years. There is now general agreement that all patients with accelerated hypertension, as manifested by high diastolic pressure and Group III and IV funduscopic changes ...
Freis, Edward D.
core +1 more source
PLoS ONE, 2014 Pancreatic ductal adenocarcinomas are desmoplastic and hypoxic, both of which are associated with poor prognosis. Hypoxia-activated prodrugs (HAPs) are specifically activated in hypoxic environments to release cytotoxic or cytostatic effectors. TH-302 is
Kate M Bailey +9 more
doaj +1 more source
Posterior reversible encephalopathy syndrome (PRES) after bevacizumab therapy for metastatic colorectal cancer. [PDF]
, 2018 Posterior reversible encephalopathy syndrome (PRES) is an increasingly recognizable neuro-clinical syndrome. Clinical and neurological manifestations of PRES include hypertension, headache, encephalopathy, seizures, and symmetrical white matter changes ...
Ghani, Ali +5 more
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Journal of Medical Case Reports, 2013 Introduction Anti-neutrophil cytoplasmic antibody-associated vasculitis has been associated with many drugs and it is a relatively rare side effect of the antihypertensive drug hydralazine.
Keasberry Justin +5 more
doaj +1 more source
Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair [PDF]
, 2015 A family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, with consequent loss of ...
Olson, Eric N., van Rooij, Eva
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Acute Low-Dose Hydralazine-Induced Lupus Pneumonitis
Case Reports in Pulmonology, 2017 A 35-year-old female was started on hydralazine 10 mg orally three times a day for treatment of postpartum hypertension. Three months later, after multiple unsuccessful courses of prednisone and antibiotics for presumed pneumonia and asthma exacerbations,
Sarah K. Holman +3 more
doaj +1 more source
Angiotensin AT1 Receptor-associated protein Arap1 in the Kidney Vasculature is Suppressed by Angiotensin II [PDF]
, 2012 Arap1 is a protein that interacts with angiotensin II type 1 (AT1) receptors and facilitates increased AT1 receptor surface expression in vitro. In the present study, we assessed the tissue localization and regulation of Arap1 in vivo.
Castrop, Hayo +7 more
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Hydralazine-Induced ANCA Vasculitis Presenting With Pericarditis: A Novel Case and Literature Review
Case Reports in CardiologyHydralazine, a commonly used arterial vasodilator for managing congestive heart failure and hypertension, is known to be associated with drug-induced lupus and, less frequently, antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). Drug-
Ahmed Sami Hammami +7 more
doaj +1 more source
Diagnosis and Treatment of Eclampsia
Journal of Cardiovascular Development and DiseaseHypertensive disorders of pregnancy affect approximately 5% to 10% of pregnant women. Eclampsia is a serious hypertensive disorder that is primarily characterized by the onset of grand mal seizure activity in the absence of other causative conditions ...
Vasiliki Katsi +3 more
doaj +1 more source