Results 71 to 80 of about 15,167 (190)

Hydralazine-Induced ANCA Vasculitis With Overlapping Features of Lupus Erythematosus

Annals of Internal Medicine: Clinical Cases
Hydralazine is associated with drug-induced lupus erythematosus (DILE) and antineutrophil cytoplasmic antibody–associated vasculitis (AAV). A 72-year-old woman receiving hydralazine presented with acute kidney injury and positive antinuclear antibody ...
Andrea Ramirez Olarte, Nicholas Strat, Laura Kidd, Krishna Navaratnam, Stephen Lindsey   +4 more
doaj   +1 more source

Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody

Case Reports in Rheumatology, 2017
Drug induced lupus erythematosus (DIL or DILE) is an autoimmune disorder caused by chronic use of certain drugs. We report a unique case of hydralazine induced lupus syndrome (HILS) with a negative antinuclear antibody in a female patient who was on ...
Praneet Iyer, Ahmed Dirweesh, Ritika Zijoo   +2 more
doaj   +1 more source

DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells. [PDF]

PLoS ONE, 2012
BACKGROUND: Down regulation of genes coding for nucleoside transporters and drug metabolism responsible for uptake and metabolic activation of the nucleoside gemcitabine is related with acquired tumor resistance against this agent.
Myrna Candelaria, Erick de la Cruz-Hernandez, Lucia Taja-Chayeb, Enrique Perez-Cardenas, Catalina Trejo-Becerril, Aurora Gonzalez-Fierro, Alma Chavez-Blanco, Ernesto Soto-Reyes, Guadalupe Dominguez, Jaenai E Trujillo, Jose Diaz-Chavez, Alfonso Duenas-Gonzalez   +11 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, Volume 15, Issue 36, 25 September 2026.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Fetal premature atrial contractions associated with hydralazine.

, 1989
Echocardiography documented fetal premature atrial contractions after maternal hydralazine treatment for hypertension. No signs of fetal congestive heart failure were noted, and other tests of fetal surveillance remained reassuring.
Lodeiro, S B, Lodeiro, J G, Feinstein, S J   +2 more
core   +1 more source

The Effect of Intensive Blood Pressure Reduction on Perihematomal Edema After Intracerebral Hemorrhage: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 16, Issue 9, September 2026.
This systematic review and meta‐analysis suggests that intensive blood pressure reduction is associated with modestly smaller approximately 24‐h perihematomal edema expansion after spontaneous intracerebral hemorrhage, supporting further standardized trials to clarify whether early edema attenuation contributes to clinical benefit.
Xianxian Li, Chengguang Zou, Yuchao Jia, Chensheng Pan, Xiaodong Ye, Suiqiang Zhu, Shanshan Huang   +6 more
wiley   +1 more source

Hydralazine Sensitizes to the Antifibrotic Effect of 5-Aza-2′-deoxycytidine in Hepatic Stellate Cells

Biology, 2020
Background: Hepatic stellate cell (HSC) activation is essential for the development of liver fibrosis. Epigenetic machinery, such as DNA methylation, is largely involved in the regulation of gene expression during HSC activation.
Kiyoshi Asada, Kosuke Kaji, Shinya Sato, Kenichiro Seki, Naotaka Shimozato, Hideto Kawaratani, Hiroaki Takaya, Yasuhiko Sawada, Keisuke Nakanishi, Masanori Furukawa, Mitsuteru Kitade, Kei Moriya, Tadashi Namisaki, Ryuichi Noguchi, Takemi Akahane, Hitoshi Yoshiji   +15 more
doaj   +1 more source

Severe Hypokalemia With Rhabdomyolysis—A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Magnesium administration should be considered in severe or refractory hypokalemia with even normal serum magnesium; however, more research is needed to establish the evidence and take into account confounding factors. Severe hypokalemia can manifest with rhabdomyolysis, which can affect kidney function.
Tahir Shahzad, Alexandra Murray
wiley   +1 more source

GO processes affected by hydralazine.

, 2013
MetaDrug™ program predicted that hydralazine may affect not only DNA methylation in cytosine but also can be involved in negative regulation of H3K9 methylation.
Enrique Perez-Cardenas (5652484), Jaenai E. Trujillo (329635), Aurora Gonzalez-Fierro (4655), Guadalupe Dominguez (329633), Erick de la Cruz-Hernandez (5652481), Lucia Taja-Chayeb (42946), Ernesto Soto-Reyes (329632), Alfonso Duenas-Gonzalez (5652487), Catalina Trejo-Becerril (42944), Myrna Candelaria (4657), Alma Chavez-Blanco (4653), Jose Diaz-Chavez (80713)   +11 more
core   +1 more source

Hydralazine combined with conventional therapy improved outcomes in severe systolic dysfunction and mitral regurgitation

ESC Heart Failure
Aims Patients with heart failure (HF) and reduced left ventricular ejection fraction (LVEF) accompanied by significant mitral regurgitation (MR) had poor outcome. Several vasodilator trials showed neutral results.
Shih‐Hung Hsiao, Chao‐Sheng Hsiao, Jau‐Wen Shiau, Kuan‐Rau Chiou   +3 more
doaj   +1 more source