Results 61 to 70 of about 15,167 (190)

A case of hydralazine-induced bullous pemphigoid

AboutOpen
Introduction: Hydralazine-induced bullous pemphigoid (BP) is a rare adverse drug reaction where the medication may act to trigger an autoimmune response against proteins in the dermal-epidermal junction (DEJ).
Paul Zammit
doaj   +1 more source

Peripartum Anesthetic Management of a Patient With Sickle Cell Disease and Preeclampsia

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Peripartum care for patients with sickle cell disease and preeclampsia requires coordinated multidisciplinary management. Key strategies include multimodal analgesia, individualized transfusion protocols, and vigilant maternal‐fetal monitoring.
Madeline Dow, Aariya Srinivasan, Sabry Ayad   +2 more
wiley   +1 more source

Prognostic Significance and Factors Associated With Worsening LV Dilatation in Heart Failure

Clinical Cardiology, Volume 49, Issue 10, October 2026.
Among patients with a hospitalization or ED visit for HF and at least two echocardiograms at least 6 months apart, failure to decrease LVESD by at least 3.13% or an increase in LVEDD of 1.33% were associated with the composite of all‐cause death, HF hospitalization, and ED visits for HF. Figure created using Canva and Servier Medical Art. ED, emergency
Tauben Averbuch, Robert J. H. Miller, Justin Ezekowitz, Jonathan G. Howlett, Finlay A. McAlister, Erik Youngson, Nowell M. Fine   +6 more
wiley   +1 more source

A Paradoxical Cerebral Hemodynamic Effect of Hydralazine

, 1975
Hydralazine is shown to have a very complex cerebral hemodynamic effect. It raises the intracranial pressure which, together with its effect upon systemic blood pressure, reduces the cerebral perfusion pressure.
JØRN OVERGAARD, ERIK SKINHØJ
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The effects of DNA methylation and histone deacetylase inhibitors on human papillomavirus early gene expression in cervical cancer, an in vitro and clinical study

Virology Journal, 2007
Background The methylation status at the human papilloma virus (HPV) genome found in pre-invasive and invasive cervical lesions suggests that neoplastic transformation can be suppressed by gene hypermethylation, whereas hypomethylation accompanies or ...
de la Cruz-Hernández Erick, Pérez-Cárdenas Enrique, Contreras-Paredes Adriana, Cantú David, Mohar Alejandro, Lizano Marcela, Dueñas-González Alfonso   +6 more
doaj   +1 more source

Hydralazine binds covalently to complement component-C4: Different reactivity of C4A AND C4B Gene-Products [PDF]

, 1985
Long-term treatment with hydralazine is sometimes associated with deposition of immune complexes and development of systemic lupus erythematosus (SLE) as an adverse side-effect. Hydralazine inhibits the covalent binding reaction of the complement protein
Law, Sai-Kit A., Edith Sim, Sim, Edith, Sai-Kit A. Law   +3 more
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Sequential carbonyl derivatives and hydrazone adduct formation on myeloperoxidase contribute to development of ANCA vasculitis

The Journal of Clinical Investigation
Drug-induced autoimmune diseases are increasingly recognized, although mechanistic insight into disease causation is lacking. Hydralazine exposure has been linked to autoimmune diseases, including antineutrophil cytoplasmic autoantibody (ANCA) vasculitis.
Gang Xi, Elizabeth A. Mclnnis, Olivier Lardinois, Peiqi Hu, John S. Poulton, Meghan E. Free, Dhruti P. Chen, Evan M. Zeitler, Eveline Y. Wu, Nicole M. Orzechowski, Vimal K. Derebail, J. Charles Jennette, Ronald J. Falk   +12 more
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Hydralazine Induces Myeloperoxidase and Proteinase 3 Anti-Neutrophil Cytoplasmic Antibody Vasculitis and Leads to Pulmonary Renal Syndrome

Case Reports in Nephrology, 2014
We report a case of hydralazine-induced ANCA-associated glomerulonephritis with pulmonary hemorrhage. A 62-year-old Hispanic man with hypertension, who was being treated with hydralazine 100 mg three times a day for four and half years, presented to the ...
Gaurav Agarwal, Ghayyath Sultan, Sherry L. Werner, Claudia Hura   +3 more
doaj   +1 more source

Mitochondrial Fusion and Fission in Age‐Related Cardio‐Cerebral Diseases: Mechanisms and Interventions

Aging Cell, Volume 25, Issue 10, October 2026.
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley   +1 more source

Cardiopulmonary control in sleeping Sprague-Dawley rats treated with hydralazine

, 1997
Carley, David W., Sinisa M. Trbovic, Alex Bozanich, and Miodrag Radulovacki. Cardiopulmonary control in sleeping Sprague-Dawley rats treated with hydralazine. J. Appl. Physiol. 83(6): 1954–1961, 1997.—To test the hypothesis that hydralazine can suppress
Alex Bozanich, Miodrag Radulovacki, Sinisa M. Trbovic, David W. Carley   +3 more
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