Results 51 to 60 of about 15,167 (190)
Hydralazine and Enzalutamide: Synergistic Partners against Prostate Cancer
Advanced prostate cancers frequently develop resistance to androgen-deprivation therapy with serious implications for patient survival. Considering their importance in this type of neoplasia, epigenetic modifications have drawn attention as alternative ...
Nair Lopes +6 more
doaj +1 more source
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Prevalence and Associations of Abnormal Levels of Vitamin B6 in People with Parkinson's Disease
Abstract Background In people with Parkinson's disease, abnormal levels of vitamin B6 may be associated with polyneuropathy and epileptic seizures, including medication‐refractory status epilepticus. Objectives To estimate the prevalence and explore associations of abnormal levels of vitamin B6 in people with Parkinson's disease.
Karlo J. Lizarraga +7 more
wiley +1 more source
Effect of hydralazine upon G9A histone methyltransferase.
A. Quantitative RT-PCR of G9A shows that resistant CaLoGR cells had an increase as compared to basal and that hydralazine reduces its expression (basal vs resistant ...
Enrique Perez-Cardenas (5652484) +11 more
core +1 more source
Anti-neoplastic properties of hydralazine in prostate cancer [PDF]
Prostate cancer (PCa) is a major cause of cancer-related morbidity and mortality worldwide. Although early disease is often efficiently managed therapeutically, available options for advanced disease are mostly ineffective.
Sousa, Elsa Joana +7 more
core +1 more source
Studies on the cardiovascular actions of hydralazine.
In conscious normotensive rabbits, the intravenous administration of hydralazine (0.3 mg/Kg) induced a significant decrease of mean arterial blood pressure (MBP) (p 0.05) and did not modify the tachycardia.
Virgílio Durão, Assunção Elvas
doaj +1 more source
ABSTRACT Cutaneous iododerma is a rare adverse reaction to iodine‐containing compounds that may clinically and histopathologically mimic infection, vasculitis, malignancy, and other neutrophilic dermatoses. Although most commonly associated with iodinated contrast exposure, a variety of predisposing factors and potential associations have been reported,
Volha Lenskaya +4 more
wiley +1 more source
Hydralazine inhibits ventricular tachyarrhythmias in an acquired long QT rabbit model
Background: Some cardioactive vasodilating agents inhibit ventricular tachyarrhythmias (VT) associated with acquired long QT syndrome (LQT). We tested whether a vasodilator without direct cardiac effect can eliminate abnormal repolarization-related VT ...
Kenta Tsutsui, MD +4 more
doaj +1 more source
Abstract Aims To evaluate the sustained impact of the Endocrine Hypertension Service on primary aldosteronism (PA) diagnosis and management over a subsequent 3‐year period. Background PA is a prevalent yet underdiagnosed cause of secondary hypertension, associated with increased cardiovascular, renal and metabolic risk. Limited awareness, resources and
Minn W. Chow +5 more
wiley +1 more source
Cerebral blood flow in conscious rats and implications for therapeutic interventions
Abstract Cerebral blood flow (CBF) often becomes compromised in patients suffering from cardiovascular diseases, increasing the risk of neurodegenerative disease and vascular dementia. There is an urgent need for treatments to address cardiovascular risk without compromising brain perfusion, yet the impact of many existing treatments on CBF are not ...
Tonja W. Emans +3 more
wiley +1 more source

