Results 31 to 40 of about 12,705 (162)

Hydralazine inhibits ventricular tachyarrhythmias in an acquired long QT rabbit model

Journal of Arrhythmia, 2014
Background: Some cardioactive vasodilating agents inhibit ventricular tachyarrhythmias (VT) associated with acquired long QT syndrome (LQT). We tested whether a vasodilator without direct cardiac effect can eliminate abnormal repolarization-related VT ...
Kenta Tsutsui, MD, Satoshi Yamagishi, MD, Tomoyuki Kunishima, MD, Noriyuki Hayami, MD, Yuji Murakawa, MD   +4 more
doaj   +1 more source

Improving primary aldosteronism diagnosis and treatment: outcomes from an endocrine hypertension service

Internal Medicine Journal, EarlyView.
Abstract Aims To evaluate the sustained impact of the Endocrine Hypertension Service on primary aldosteronism (PA) diagnosis and management over a subsequent 3‐year period. Background PA is a prevalent yet underdiagnosed cause of secondary hypertension, associated with increased cardiovascular, renal and metabolic risk. Limited awareness, resources and
Minn W. Chow, Chrislyn Ng, Jimmy Shen, Peter J. Fuller, Jun Yang, Renata Libianto   +5 more
wiley   +1 more source

Initiation or continuation of oral labetalol versus extended‐release nifedipine in expectant management of preeclampsia with severe features

Pregnancy, Volume 2, Issue 5, September 2026.
Abstract Introduction Preeclampsia with severe features remains a major contributor to maternal and neonatal morbidity. In select patients <34 weeks, expectant management may safely prolong pregnancy and improve neonatal outcomes. Oral labetalol and extended‐release nifedipine are commonly used for blood pressure control in this setting; however ...
Ryan Farias, Christopher Ennen
wiley   +1 more source

A case of hydralazine-induced bullous pemphigoid

AboutOpen
Introduction: Hydralazine-induced bullous pemphigoid (BP) is a rare adverse drug reaction where the medication may act to trigger an autoimmune response against proteins in the dermal-epidermal junction (DEJ).
Paul Zammit
doaj   +1 more source

The effects of DNA methylation and histone deacetylase inhibitors on human papillomavirus early gene expression in cervical cancer, an in vitro and clinical study

Virology Journal, 2007
Background The methylation status at the human papilloma virus (HPV) genome found in pre-invasive and invasive cervical lesions suggests that neoplastic transformation can be suppressed by gene hypermethylation, whereas hypomethylation accompanies or ...
de la Cruz-Hernández Erick, Pérez-Cárdenas Enrique, Contreras-Paredes Adriana, Cantú David, Mohar Alejandro, Lizano Marcela, Dueñas-González Alfonso   +6 more
doaj   +1 more source

Effectiveness of nifedipine, labetalol, and hydralazine as emergency antihypertension in severe preeclampsia: a randomized control trial [version 2; peer review: 2 approved]

F1000Research, 2023
Background: Preeclampsia is a highly prevalent disease among pregnant women. In the event of hypertensive emergency, nifedipine, labetalol, and hydralazine are assigned as first-line therapies in preeclampsia.
Maya Savira, Dhini Aiyulie Novri, Yulis Hamidy, Donel S   +3 more
doaj   +1 more source

The Feasibility and Acceptability of a Collaborative Deprescribing Intervention to Reduce Anticholinergic Burden Among Hospitalised Older Patients

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Introduction 37%–48% of older patients receive anticholinergic medicines, increasing the risk for falls, delirium, dementia and death. Hospital admission may provide an opportunity for deprescribing to improve outcomes. This study evaluated the feasibility and acceptability of a digital tool to identify anticholinergic medicines and support ...
Kinda Ibrahim, Eloise Radcliffe, Edward Hewertson, Andrew Bates, Andy Fox, Emily Smith, Cathrine Mckenzie, Liam Jones, Sara Mckelvie, Ngianga Ii Kandala, Sara McCloskey, Tracey Sach, Stephen Lim   +12 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, Volume 600, Issue 16, Page 2226-2247, August 2026.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Diabetic Striatopathy in a Middle‐Aged African Woman With Poorly Controlled Type 2 Diabetes Mellitus and HIV Coinfection—A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Diabetic striatopathy is a reversible cause of acute chorea occurring in patients with poorly controlled diabetes mellitus, including those even with complex comorbidities like HIV. Timely neuroimaging and prompt metabolic correction are crucial, emphasizing the need for high clinical suspicion.
Kojo Awotwi Hutton‐Mensah, Francis Asante Baadu, Allswell Ackon, Alfred Opata, Ranis Anamon Amon, Frank Micah   +5 more
wiley   +1 more source

Hydralazine Induces Myeloperoxidase and Proteinase 3 Anti-Neutrophil Cytoplasmic Antibody Vasculitis and Leads to Pulmonary Renal Syndrome

Case Reports in Nephrology, 2014
We report a case of hydralazine-induced ANCA-associated glomerulonephritis with pulmonary hemorrhage. A 62-year-old Hispanic man with hypertension, who was being treated with hydralazine 100 mg three times a day for four and half years, presented to the ...
Gaurav Agarwal, Ghayyath Sultan, Sherry L. Werner, Claudia Hura   +3 more
doaj   +1 more source