Results 21 to 30 of about 21,060 (203)

Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet.

open access: yesPLoS ONE, 2021
BackgroundMaternal high fat diet (HFD) promotes chronic kidney disease (CKD) in offspring. This is in accordance with the theory of fetal programming, which suggests adverse conditions occurring in utero predispose offspring to chronic conditions later ...
Benjamin P Larkin   +7 more
doaj   +1 more source

Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats [PDF]

open access: yes, 2015
Hypertension-induced structural remodeling of the left atrium (LA) has been suggested to involve the renin–angiotensin system. This study investigated whether treatment with an angiotensin receptor blocker, candesartan, regresses atrial remodeling in ...
Choisy, Stéphanie C.   +5 more
core   +1 more source

Variations in Arterial Blood Pressure after Kidney Transplantation [PDF]

open access: yes, 1973
The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients.
CORMAN, JACQUES L   +7 more
core   +1 more source

ANA-Negative Hydralazine-Induced Pericardial Effusion

open access: yesCase Reports in Medicine, 2017
This case describes a patient with pericardial effusion as a phenomenon of the drug-induced lupus erythematosus (DILE) syndrome due to hydralazine. The relevance of this case report lies in the fact that although hydralazine has been a known causative ...
Vicken Zeitjian, Azar Mehdizadeh
doaj   +1 more source

Safety and efficacy of blood exchange transfusion for priapism complicating sickle cell disease. [PDF]

open access: yes, 2016
BACKGROUND: Priapism is unwanted painful penile erection that affects about 36% of boys and men with sickle cell disease (SCD) most of whom have sickle cell anemia. Clinically, priapism could be stuttering, minor, or major.
Adeyoju   +23 more
core   +2 more sources

Inhibition of α2-adrenoceptor is renoprotective in 5/6 nephrectomy-induced chronic kidney injury rats

open access: yesJournal of Pharmacological Sciences, 2021
In the present study, we investigated the renoprotective effects of long-term treatment with yohimbine, an α2-adrenoceptor inhibitor, in a 5/6 nephrectomy-induced chronic kidney disease (CKD) rat model.
Kohei Hayashi   +3 more
doaj   +1 more source

Drug-induced vasculitis

open access: yesIndian Journal of Rheumatology, 2019
Vascular injury due to drugs is recognized as a distinct entity under the Chapel Hill Consensus Conference 2012 definitions for vasculitis. Drug-induced vasculitis (DIV) may affect various types of vessels.
Durga Prasanna Misra   +2 more
doaj   +1 more source

Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]

open access: yes, 2014
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad   +6 more
core   +2 more sources

Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway

open access: yesNature Communications, 2017
Hydralazine is an FDA approved drug for the treatment of hypertension. Here, Dehghan et al. report that hydralazine triggers the cellular oxidative stress response by activating NRF2/SKN-1 signaling and extends C.
Esmaeil Dehghan   +11 more
doaj   +1 more source

His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]

open access: yes, 1988
The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M.   +3 more
core   +1 more source

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