Results 21 to 30 of about 15,167 (190)

Potential Impacts of Hydralazine as a Novel Antioxidant on Cardiovascular and Renal Disease—Beyond Vasodilation and Blood Pressure Lowering

Antioxidants, 2022
Hydralazine is a traditional antihypertensive drug that was developed several decades ago. Its most well-known effect is blood pressure lowering by arterial vasodilation.
Ting-Ting Chang, Jaw-Wen Chen
doaj   +1 more source

Genotype-Guided Hydralazine Therapy [PDF]

, 2020
Background: Despite its approval in 1953, hydralazine hydrochloride continues to be used in the management of resistant hypertension, a condition frequently managed by nephrologists and other clinicians.
Cooper-DeHoff, Rhonda M., Zhao, Yang, Woodcock, Alexander M., Eadon, Michael T., Elchynski, Amanda L., Collins, Kimberly S., Raviele, Anthony L.J.   +6 more
core   +1 more source

Hydralazine-associated adverse events: a report of two cases of hydralazine-induced ANCA vasculitis

, 2018
Hydralazine is a direct-acting vasodilator, which has been used in treatment for hypertension (HTN) since the 1950s. While it is well known to cause drug-induced lupus (DIL), recent reports are indicating the emergence of the drug-induced anti-neutrophil
Harry Dounis (5187446), Mayurkumar Patel (5187443), Eric J Costanzo (5187449), Seyedehsara Seyedali (5187440), Roman Zuckerman (5187395), Rany Al Haj (5187452), Arif Asif (5187401)   +6 more
core   +3 more sources

Hydralazine protects the heart against acute ischemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission [PDF]

, 2021
Aims: Genetic and pharmacological inhibition of mitochondrial fission induced by acute myocardial ischaemia/reperfusion injury (IRI) has been shown to reduce myocardial infarct size.
Samangouei, Parisa, Riquelme Meléndez, Jaime Andrés, Holien, Jessica K., Hausenloy, DJ, Lees, JG, Rosdah, Ayeshah A., Samangouei, P, Ketteler, Robin, Lim, SY, Kriston-Vizi, Janos, Simoes Da Costa, Joanna Rodrigues, Crespo-Avilan, GE, Chinda, Kroekkiat, Kalkhoran, SB, Ling, NXY, Crespo Avilan, Gustavo E., Kalkhoran, Siavash Beikoghli, Hausenloy, Dereck J., Hernandez-Resendiz, S, Chinda, K, Riquelme, JA, Yap, EP, Ling, Naomi X. Y., Yellon, Derek M., Yap, En Ping, Kriston-Vizi, J, Da Costa, JRS, Hernández Resendiz, Sauri, Lees, Jarmon G., Rosdah, AA, Ketteler, R, Lim, Shiang Y., Yellon, DM, Holien, JK   +33 more
core   +2 more sources

Overlapping Syndromes: Drug-Induced Vasculitis From Hydralazine With Positive Antinuclear Antibodies

Clinical Medicine Insights: Case Reports, 2023
Hydralazine is an antihypertensive medication that has been associated with drug-associated autoimmune syndromes like interstitial lung disease, pauci-immune glomerulonephritis, and hypocomplementemia.
Lakshmi Kannan, UmmeRubab Syeda
doaj   +1 more source

Hydralazine-induced vasculitis presenting with ocular manifestations

American Journal of Ophthalmology Case Reports, 2022
Purpose: The objective of the study is to report a case of ocular manifestations in a patient with hydralazine-induced vasculitis. Observations: An 88-year-old female was admitted for lower gastrointestinal bleeding.
Vivian S. Hawn, Thomas A. Vo, David Flomenbaum, Richard P. Gibralter   +3 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Consequences of treatment by hydralazine and the association hydralazine-celiprolol.

, 2022
The upper panels represent the survival curves on either active treatment or water. The lower panels represent SBP (lower bars: left scale) and HR (upper lines: right scale), measured between 8 and 24 weeks. Data are expressed as mean ±SEM.
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
core   +1 more source

The alteration of neuronal activities of the cuneiform nucleus in non-hypovolemic and hypovolemic hypotensive conditions

Arquivos de Neuro-Psiquiatria, 2021
Background: The cuneiform nucleus is located in the center of the circuit that mediates autonomic responses to stress. Hemorrhagic hypotension leads to chemoreceptor anoxia, which consequently results in the reduction of baroreceptor discharge and ...
Reza Mohebbati, Hassan Abbassian, Mohammad Naser Shafei, Ali Gorji, Sajad Sahab Negah   +4 more
doaj   +1 more source

Comparison of the Efficacy of Nifedipine and Hydralazine in Hypertensive Crisis in Pregnancy [PDF]

Acta Medica Iranica, 2011
Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy. Oral nifedipine is an alternative in management of these patients.
Zahra Rezaei, Fatemeh Rahimi Sharbaf, Mino Pourmojieb, Yashar Youefzadeh-Fard, Manijeh Motevalian, Zahra Khazaeipour, Sara Esmaeili   +6 more
doaj   +1 more source