Results 1 to 10 of about 21,060 (203)

Hydralazine augmented ultrasound hyperthermia for the treatment of hepatocellular carcinoma

open access: yesScientific Reports, 2021
This study investigates the use of hydralazine to enhance ultrasound hyperthermia for the treatment of hepatocellular carcinoma (HCC) by minimizing flow-mediated heat loss from the tumor.
Mrigendra B. Karmacharya   +3 more
doaj   +1 more source

Novel Role of Gestational Hydralazine in Limiting Maternal and Dietary Obesity-Related Chronic Kidney Disease

open access: yesFrontiers in Cell and Developmental Biology, 2021
BackgroundMaternal obesity is a risk factor for chronic kidney disease (CKD) in offspring, underpinning the theory of the developmental origins of health and disease.
Benjamin P. Larkin   +9 more
doaj   +1 more source

Potential Impacts of Hydralazine as a Novel Antioxidant on Cardiovascular and Renal Disease—Beyond Vasodilation and Blood Pressure Lowering

open access: yesAntioxidants, 2022
Hydralazine is a traditional antihypertensive drug that was developed several decades ago. Its most well-known effect is blood pressure lowering by arterial vasodilation.
Ting-Ting Chang, Jaw-Wen Chen
doaj   +1 more source

Overlapping Syndromes: Drug-Induced Vasculitis From Hydralazine With Positive Antinuclear Antibodies

open access: yesClinical Medicine Insights: Case Reports, 2023
Hydralazine is an antihypertensive medication that has been associated with drug-associated autoimmune syndromes like interstitial lung disease, pauci-immune glomerulonephritis, and hypocomplementemia.
Lakshmi Kannan, UmmeRubab Syeda
doaj   +1 more source

Hydralazine-induced vasculitis presenting with ocular manifestations

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: The objective of the study is to report a case of ocular manifestations in a patient with hydralazine-induced vasculitis. Observations: An 88-year-old female was admitted for lower gastrointestinal bleeding.
Vivian S. Hawn   +3 more
doaj   +1 more source

The alteration of neuronal activities of the cuneiform nucleus in non-hypovolemic and hypovolemic hypotensive conditions

open access: yesArquivos de Neuro-Psiquiatria, 2021
Background: The cuneiform nucleus is located in the center of the circuit that mediates autonomic responses to stress. Hemorrhagic hypotension leads to chemoreceptor anoxia, which consequently results in the reduction of baroreceptor discharge and ...
Reza Mohebbati   +4 more
doaj   +1 more source

Hydralazine Associated With Reduced Therapeutic Phlebotomy Frequency in a Nationwide Cohort Study: Real-World Effectiveness for Drug Repurposing

open access: yesFrontiers in Pharmacology, 2022
Background: Therapeutic phlebotomy, known as scheduled bloodletting, has been the main method for managing erythrocytosis symptoms and thrombocytosis-associated complications in various blood disorders.
Wei-Zhi Lin   +11 more
doaj   +1 more source

Comparison of the Efficacy of Nifedipine and Hydralazine in Hypertensive Crisis in Pregnancy [PDF]

open access: yesActa Medica Iranica, 2011
Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy. Oral nifedipine is an alternative in management of these patients.
Zahra Rezaei   +6 more
doaj   +1 more source

Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines

open access: yesCancer Cell International, 2006
Background Among the epigenetic alterations occurring in cancer, DNA hypermethylation and histone hypoacetylation are the focus of intense research because their pharmacological inhibition has shown to produce antineoplastic activity in a variety of ...
Candelaria Myrna   +11 more
doaj   +1 more source

Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP+ and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway

open access: yesFrontiers in Neurology, 2019
Although the pathogenic mechanisms of Parkinson's disease (PD) remain unclear, ample empirical evidence suggests that oxidative stress is involved in the pathogenesis of this disease.
Xingfang Guo   +12 more
doaj   +1 more source

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