Results 1 to 10 of about 12,705 (162)
Impact of N-Acetylation on DNA Damage and Oxidative Stress Responses in Mammalian Cells and Human Hepatocytes Treated with Hydralazine [PDF]
BiomoleculesHydralazine is widely used to treat hypertension during pregnancy and has epigenetic effects in cancer therapy. Cryoplatable human hepatocytes showed concentration-dependent increase in DNA damage response (linear trend p = 0.0069) following 24 h ...
Mariam R. Habil +7 more
doaj +2 more sources
A study of redox properties of hydralazine hydrochloride, an antihypertensive drug
Journal of Saudi Chemical Society, 2010 Hydralazine hydrochloride itself is a reducing agent and its redox properties like other reducing agents vary as the oxidizing agent and applied conditions vary. The redox properties of hydralazine were studied by spectrophotometric method.
Saima Imad +2 more
exaly +2 more sources
Hydralazine Attenuates Lipopolysaccharide-Induced Murine Myocardial Dysfunction by Inhibition of Semicarbazide-Sensitive Amine Oxidase [PDF]
AntioxidantsSepsis-induced myocardial dysfunction (SIMD) is a fatal complication with limited therapeutic options. Semicarbazide-sensitive amine oxidase (SSAO) contributes to oxidative stress and leukocyte recruitment, yet its role in SIMD remains unexplored.
Zejian Kuang +5 more
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Hydralazine augmented ultrasound hyperthermia for the treatment of hepatocellular carcinoma
Scientific Reports, 2021 This study investigates the use of hydralazine to enhance ultrasound hyperthermia for the treatment of hepatocellular carcinoma (HCC) by minimizing flow-mediated heat loss from the tumor.
Mrigendra B. Karmacharya +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 BackgroundMaternal obesity is a risk factor for chronic kidney disease (CKD) in offspring, underpinning the theory of the developmental origins of health and disease.
Benjamin P. Larkin +9 more
doaj +1 more source
Antioxidants, 2022 Hydralazine is a traditional antihypertensive drug that was developed several decades ago. Its most well-known effect is blood pressure lowering by arterial vasodilation.
Ting-Ting Chang, Jaw-Wen Chen
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Overlapping Syndromes: Drug-Induced Vasculitis From Hydralazine With Positive Antinuclear Antibodies
Clinical Medicine Insights: Case Reports, 2023 Hydralazine is an antihypertensive medication that has been associated with drug-associated autoimmune syndromes like interstitial lung disease, pauci-immune glomerulonephritis, and hypocomplementemia.
Lakshmi Kannan, UmmeRubab Syeda
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Hydralazine-induced vasculitis presenting with ocular manifestations
American Journal of Ophthalmology Case Reports, 2022 Purpose: The objective of the study is to report a case of ocular manifestations in a patient with hydralazine-induced vasculitis. Observations: An 88-year-old female was admitted for lower gastrointestinal bleeding.
Vivian S. Hawn +3 more
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Arquivos de Neuro-Psiquiatria, 2021 Background: The cuneiform nucleus is located in the center of the circuit that mediates autonomic responses to stress. Hemorrhagic hypotension leads to chemoreceptor anoxia, which consequently results in the reduction of baroreceptor discharge and ...
Reza Mohebbati +4 more
doaj +1 more source
Comparison of the Efficacy of Nifedipine and Hydralazine in Hypertensive Crisis in Pregnancy [PDF]
Acta Medica Iranica, 2011 Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy. Oral nifedipine is an alternative in management of these patients.
Zahra Rezaei +6 more
doaj +1 more source