Results 81 to 90 of about 21,060 (203)
Rationale and design of the GUIDE-IT study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure. [PDF]
, 2014 OBJECTIVES: The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) study is designed to determine the safety, efficacy, and cost-effectiveness of a strategy of adjusting therapy with the goal of achieving and
Adams, Kirkwood F. +15 more
core +3 more sources
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Hypertension drives cognitive decline through a previously unrecognized CCN1–integrin αvβ6–TGF‐β signaling axis that culminates in mitochondrial dysfunction and hippocampal neuronal injury. In this pathway, angiotensin II induces CCN1 upregulation, which activates αvβ6 integrin‐mediated release of latent TGF‐β, triggering SMAD2/3 phosphorylation and ...
Xufang Huo +10 more
wiley +1 more source
Development of an analytical method to determine malondialdehyde as an oxidative marker in cryopreserved bovine semen [PDF]
, 2015 Frozen sperm is widely used in artificial insemination of cattle as well as other animal species. As a consequence of the freezing and thawing processes of semen, an excess of reactive oxygen species (ROS) are formed.
Nazareno, Mónica Azucena +3 more
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Arthritis &Rheumatology, Volume 78, Issue 3, Page 654-664, March 2026.Objective Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) and sodium‐glucose cotransporter 2 inhibitors (SGLT2i) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear.
Derin Karacabeyli +4 more
wiley +1 more source
DNA methylation and trinucleotide repeat expansion diseases [PDF]
, 2012 Copyright @ 2012 InTechThis article has been made available through the Brunel Open Access Publishing Fund.This article is made available through the Brunel Open Access Publishing ...
Pook, M
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Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT Hypertension is common in autosomal‐dominant polycystic kidney disease (ADPKD) but may occasionally reflect a secondary etiology. We report a 71‐year‐old man with ADPKD and end‐stage renal disease who developed persistent, refractory hypertension following renal transplantation despite multidrug therapy and bilateral native nephrectomy ...
Matthew Wainstein +7 more
wiley +1 more source
Anti-proliferative Effects of Hydralazine on K562 Cell Line (CML)
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2017 Introduction: Cancer is the second leading cause of death in the world and among the types of cancer, leukemia is one of the deadliest. Chronic myeloid leukemia (CML) is the best known types of leukemia. Hydralazine is in the cardiovascular medical group,
Sonya Dadakhani +2 more
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Hydralazine-associated antineutrophil cytoplasmic antibody vasculitis with pulmonary-renal syndrome [PDF]
, 2018 Hydralazine, a vasodilator, is commonly used as an adjunctive treatment for moderate to severe hypertension, heart failure and hypertensive emergencies in pregnancy. Hydralazine-induced lupus was first described in 1953. Clinical presentation ranges from
Aeddula, Narothama Reddy +3 more
core +1 more source
Elastic behaviour of the carotid artery in intact spontaneously hypertensive rats [PDF]
, 2017 Intact spontaneously hypertensive rats (SHR) were studied to assess the effect of prolonged antihypertensive treatment on the elastic behaviour of the external carotid artery.
Brunner, H. R. +5 more
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