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Natural Alkaloid Waltherione F-Derived Hydrazide Compounds Evaluated in an Agricultural Fungicidal Field.

Journal of Agricultural and Food Chemistry, 2023
In this project, quinoline and quinolone-containing hydrazide compounds were designed and synthesized by introducing a bioactive hydrazide group into the skeleton of waltherione F.
Zhan Chen   +13 more
semanticscholar   +1 more source

Toughening Hydrogels by forming Robust Hydrazide-transition Metal Coordination Complexes.

Chemistry, 2023
Energy dissipation based on dynamic fracture of metal ligands is one of effective means to toughen hydrogel materials for specific applications in biomedical and engineering fields. Exploration of new kinds of metal-ligand coordinates with robust bonding
Huaqiang Ju   +6 more
semanticscholar   +1 more source

Copper-Hydrazide Coordinated Multifunctional Hyaluronan Hydrogels for Infected Wound Healing.

ACS Applied Materials and Interfaces, 2022
Bacterial infection and delayed healing are two major obstacles in cutaneous wound management, and developing multifunctional hydrogels with antibacterial and prohealing capabilities presents a promising strategy to dress wounds.
Junmin Qian   +6 more
semanticscholar   +1 more source

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation.

Journal of Medicinal Chemistry, 2022
In this study, we report the first highly selective HDAC6 inhibitor with hydrazide as the zinc-binding group (ZBG), which displays superior pharmacokinetic properties to the current hydroxamic acid inhibitors.
Kairui Yue   +7 more
semanticscholar   +1 more source

Potent Hydrazide-Based HDAC Inhibitors with a Superior Pharmacokinetic Profile for Efficient Treatment of Acute Myeloid Leukemia In Vivo.

Journal of Medicinal Chemistry, 2021
As "Michael acceptors" may induce promiscuous responses in mammalian cells by reacting with various proteins, we modified the cinnamamide of our previous hydrazide-based HDAC inhibitors (HDACIs) to deactivate the Michael reaction. Representative compound
Yuqi Jiang   +12 more
semanticscholar   +1 more source

Flexible and Semi-flexible Amide-Hydrazide Decorated Fluorescent Covalent Organic Frameworks as On-Off pH Responsive Proton Scavengers.

ACS Applied Materials and Interfaces, 2021
One of the desired ways to improve robustness and crystallinity in the covalently linked reticular frameworks is through the incorporation of varied and key functionalities in these promising materials.
Prasenjit Das, S. Mandal
semanticscholar   +1 more source

Design, Synthesis and Spectroscopic Characterizations of Medicinal Hydrazide Derivatives and Metal Complexes of Malonic Ester

Current Bioactive Compounds, 2021
A new series of malonic acid-based hydrazide derivatives (BPMPDH, 2HPMPDH, 3HPMPDH, 4HPMPDH, DMPDH) are successfully synthesized by the reaction of malonic ester hydrazide with various substituted aldehydes like salicylaldehyde, benzaldehyde, 4 ...
S. Parveen   +6 more
semanticscholar   +1 more source

Trifluoromethanesulfonic Hydrazides

Russian Journal of Organic Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
B. A. Shainyan   +3 more
openaire   +1 more source

Zinc Hydrazides and Hydrazide‐Alkoxides with Cyclic and Acyclic Hydrazide Substituents

Zeitschrift für anorganische und allgemeine Chemie, 2008
AbstractThe tetrameric organometallic zinc hydrazides the {(RZn)4[NHN(CH2)n]4} (R = Me, Et, iPr and n = 5, 4) (1–6), were prepared by alkane elimination from dialkyl zinc solutions and the ring‐substituted hydrazine derivatives 1‐aminopiperidine and 1‐aminopyrrolidine at ambient temperature. They were characterized by NMR (1H, 13C) and IR spectroscopy,
Jana, Surajit   +2 more
openaire   +1 more source

Synthesis of promising antimicrobial agents: hydrazide‐hydrazones of 5‐nitrofuran‐2‐carboxylic acid

Chemical Biology and Drug Design, 2020
In this research, we synthesized and evaluated for in vitro antimicrobial activity a new series of hydrazide‐hydrazones obtained from 5‐nitrofuran‐2‐carboxylic acid. New compounds were identified and characterized by spectral methods (1H NMR and 13C NMR).
Łukasz Popiołek   +3 more
semanticscholar   +1 more source

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