Results 121 to 130 of about 9,447 (241)
ChemMedChem, Volume 21, Issue 8, 28 April 2026.Histone deacetylase 8 (HDAC8) is a clinically validated target in neuroblastoma, where isoform selective inhibition offers a strategy to suppress tumour growth while limiting off‐target toxicity. Hydroxamic acids remain the dominant zinc‐binding group (ZBG) in HDAC inhibitors but are also associated with metabolic instability, suboptimal ...
Nathan Long +3 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 16, 25 April 2026.A sustainable, ligand‐free Pd‐catalyzed borrowing hydrogen protocol in a biodegradable hydrophobic natural deep eutectic solvent (NADES) (thymol/DL‐menthol) enables the N‐alkylation of primary amines with benzylic alcohols under mild, aerobic conditions, allowing efficient reuse of both catalyst and solvent for seven consecutive cycles. The hydrophobic
Maryam Saeb +5 more
wiley +1 more source
, 2019 Citation: 'hydrazide imides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02878 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Hypervalent Iodine‐Mediated Synthesis of Sulfones Using Organozinc Pivalates and Sulfinate Salts
European Journal of Organic Chemistry, Volume 29, Issue 13, 13 April 2026.A general protocol for sulfone synthesis via sulfonyl‐containing hypervalent iodine reagents and organozinc pivalates is described. The method is practical, provides a broad scope of sulfone in moderate to high yield. bicyclo[1.1.1]pentane‐sulfones are also disclosed and a one‐pot synthesis of Diels–Alder adduct is presented. Sulfones are key motifs in
José C. Cunha +4 more
wiley +1 more source
(dme)MCl_3(NNPh_2) (dme= dimethoxyethane; M= Nb, Ta): A Versatile Synthon for [Ta═NNPh_2] Hydrazido(2-) Complexes [PDF]
, 2010 Complexes (dme)TaCl_3(NNPh_2) (1) and (dme)NbCl_3(NNPh_2) (2) (dme =1,2-dimethoxyethane) were synthesized from MCl5 and diphenylhydrazine via a Lewis-acid assisted dehydrohalogenation reaction. Monomeric 1 has been characterized by X-ray, IR, UV−vis, ^(1)
Bercaw, John E., Tonks, Ian A.
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6-Amidinopurines as convenient precursors to pyrimido[5,4-d]pyrimidines for sar studies on Mycobacterium tuberculosis [PDF]
, 2012 Thanks are due to University of Minho and Fundação para a Ciência e Tecnologia for financial support (project nºF-COMP-01-0124-FEDER-022716 (ref. FCT PEst-/QUI/UI0686/2011) FEDER-COMPETE, FCT-Portugal and PhD grant awarded to Ana Bacelar SRFH/BD/24959 ...
Bacelar, Ana Helena Dias +4 more
core
Design and Bioactivity Evaluation of Chloro-Substituted Hydrazones
ProceedingsAroylhydrazones, created by combining aromatic aldehydes and hydrazides, have numerous biological effects such as analgesic, anti-inflammatory, anticancer, antimicrobial, and antibacterial [...]
Boryana Nikolova-Mladenova
doaj +1 more source
Petasis Three-Component Coupling Reactions of Hydrazides for the Synthesis of Oxadiazolones and Oxazolidinones [PDF]
, 2012 Batey R. A. +39 more
core +1 more source
Decoding the Nested, Multicycle Mechanism of Ni-Catalyzed Redox-Neutral Cross-Coupling through Temperature Scanning Reaction Calorimetry. [PDF]
J Am Chem SocCagan DA +5 more
europepmc +1 more source