Results 101 to 110 of about 9,447 (241)

New 4-(Morpholin-4-Yl)-3-Nitrobenzhydrazide Based Scaffold: Synthesis, Structural Insights, and Biological Evaluation

Molecules
The search for new antimicrobial agents is one of the major challenges in contemporary medicinal chemistry due to the global issue of increasing drug resistance.
Michał Janowski, Sara Janowska, Sylwia Andrzejczuk, Urszula Kosikowska, Radomir Jasiński, Barbara Mirosław, Marcin Feldo, Monika Wujec, Oleg M. Demchuk   +8 more
doaj   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli, Deborah Rudin, Dino Luethi, Matthias E. Liechti, Sabrine Bilel, Matteo Marti, Henrik Green, Manuela Carla Monti, Caitlyn Norman   +8 more
wiley   +1 more source

Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes

, 2014
The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years.
Aebersold, R., Frydman, J., Förster, F., Joachimiak, L., Leitner, A., Unverdorben, P., Walzthoeni, T.   +6 more
core   +1 more source

Determination of the Primary Molecular Target of 1,2,4-Triazole-Ciprofloxacin Hybrids [PDF]

, 2015
We have synthesized and examined the antibacterial activity, toxicity and affinity towards bacterial type II topoisomerases of a series of 1,2,4-triazole-ciprofloxacin hybrids.
Agata Paneth, Aleksandra Strzelczyk, Anna Malm, Barbara Kaproń, Barbara Rajtar, Dalhoff, Małgorzata Polz-Dacewicz, Oliphant, Paweł Stączek, Sharma, Tomasz Plech, Urszula Kosikowska, Łukasz Świątek   +12 more
core   +2 more sources

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Synthesis, structures and Hirshfeld surface analyses of 2-hydroxy-N′-methylacetohydrazide and 2-hydroxy-N-methylacetohydrazide

Acta Crystallographica Section E: Crystallographic Communications
The structures of the title compounds 2-hydroxy-N′-methylacetohydrazide, 1, and 2-hydroxy-N-methylacetohydrazide, 2, both C3H8N2O2, as regioisomers differ in the position of the methyl group relative to the N atoms in 2-hydroxy-acetohydrazide.
Oleksandr V. Vashchenko, Dmytro M. Khomenko, Viktoriya V. Dyakonenko, Rostyslav D. Lampeka   +3 more
doaj   +1 more source

Understanding Conformational Preferences of Atropisomeric Hydrazides and Its Influence on Excited State Transformations in Crystalline Media

Molecules, 2019
Hydrazides derivatives were evaluated to understand the role of N−N bond in dictating the outcome of photoreactions in the solid state.
Akila Iyer, Angel Ugrinov, J. Sivaguru
doaj   +1 more source

In vitro antimicrobial activity and DNA cleavage studies: synthesis and characterization of novel M(II) complexes with tridentate [ONO] donor Schiff base ligand derived from phenylpropane hydrazide [PDF]

, 2014
Three new ternary complexes of general formulation [M(L)​n] (1-​3)​, where L = N'-​(5-​chloro-​2-​hydroxybenzylidine)​-​3-​phenylpropane hydrazide; n = 2; M = Cu, Ni, Zn, complexes are synthesized, characterized by various physicochem.
Aradhya, S.M., Chetana, P.R., Policegoudra, R.S., Somashekar, M.N., Srinatha, B.S.   +4 more
core  

Investigation of Covalent Adaptable Networks (CANs) Based on Dynamic Acylhydrazone Bonds Featuring Shape‐Memory Ability

Journal of Applied Polymer Science, Volume 143, Issue 18, May 10, 2026.
Application of dynamic acylhydrazones to achieve CANs with shape‐memory properties. ABSTRACT Covalent adaptable networks (CANs) are based on reversible crosslinks, which are present within the polymer network structure. Due to these reversible moieties, CANs feature interesting properties/abilities such as self‐healing after damage, shape‐memory ...
Farhad Shohraty, Michael F. Agyemang, Michael Klein, Stefan Zechel, Michael Schmitt, Jürgen Popp, Martin D. Hager   +6 more
wiley   +1 more source

Synthesis and biological evaluation of new hydrazide-Schiff bases

Bangladesh Journal of Pharmacology, 2015
A new series of N-({5-(substituted aryl)-furan-2-yl}-methylidene)-hydrazides were synthesized with a new class of Schiff bases derived from the reaction of substituted phenyl-1-ketohydrazide 2 or 2-(4-chloro-3-methylaryloxy) acetohydrazide 3 with ...
Asif Husain, Munendra M. Varshney, Versha Parcha, Aftab Ahmad, Shah Alam Khan   +4 more
doaj   +1 more source