Results 81 to 90 of about 3,055 (201)
A review of hydrazide-hydrazone metal complexes’ antitumor potential
Frontiers in Chemical BiologyCancer inflicts a tremendous burden on modern society, and more effective and selective treatments need to be developed. Metallodrugs have been extensively explored as alternatives to current chemotherapeutic regimens that suffer from shortcomings such ...
Nádia Ribeiro, Isabel Correia
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Advanced Science, Volume 13, Issue 32, 9 June 2026.This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu +7 more
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High Strength, Healable, Recyclable Ionogel Capable of Long‐term Load Cycling
Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.An ionogel, engineered using hydrogen bonding to replicate the β‐sheet nanocrystals and soft amorphous protein matrix of spider silk, demonstrates a high mechanical strength of 12.6 MPa and toughness of 85.7 MJ m−3. It exhibits exceptional strain responsiveness ranging from 0.1% to 200% and remarkable long‐term cyclic durability, offering a strong ...
Haoyu Wu, Tian Jiang
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The Role of N6‐Methyladenosine Modification in Health and Disease
MedComm, Volume 7, Issue 6, June 2026.N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
, 2019 Citation: 'hydrazide hydrazones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02877 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.The polyphasic approach (morphology, physiology, biochemistry and genetics) was used to characterize Acetobacter indonesiensis strain UNPADCC 01‐5, which was isolated from oncom merah. The strain's potential as a culture for acidic fermentations and a biofunctional agent was supported by its adaptive characteristics, which included acid tolerance ...
Yolani Syaputri +9 more
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Molecular Plant Pathology, Volume 27, Issue 6, June 2026.A Cu2+‐regulated bZIP–HD‐ZIP transcriptional cascade activates ABA‐dependent immunity in apple. ABSTRACT Transcription factor‐mediated integration of hormonal signalling is central to plant immunity, yet how such regulatory modules are activated by external signals in perennial fruit crops remains largely unknown.
Hongjia Yu +5 more
wiley +1 more source
Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application
European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
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1,2‐Diazetidines − Structure, Synthesis, and Functionalization
European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
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Development of a Cu‐Catalyzed Regioselective Hydrazidation of 1,2‐Diborylalkenes
Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.Alkene 1,2‐diboronate esters undergo a Cu‐catalyzed regioselective addition to azodicarboxylates to generate functionalized borylated hydrazides. An investigation of mono‐ versus di‐hydrazidation processes and the use of these products in synthesis are described.
Kavya Gopakumar +4 more
wiley +1 more source