Results 81 to 90 of about 9,447 (241)
New resource-efficient and green synthesis methods for biologically active derivatives of urea [PDF]
, 2017 Developed were highly effective solvent-free processes for preparation of substituted ureas containingpharmacophore substituents (benzhydryl ureas, dihydroquinazolinones, semicarbazones, thiosemicarbazonesand guanylhydrazones), consistent with green ...
Filimonov, Viktor Dmitrievich +3 more
core +2 more sources
1,2‐Diazetidines − Structure, Synthesis, and Functionalization
European Journal of Organic Chemistry, EarlyView.1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
wiley +1 more source
Synthesis and Characterization of Oxomolybdenum and Oxovanadium Complexes [PDF]
, 2010 Synthesis and characterization of two different O-N donor hydrazide ligands and their corresponding dioxomolybdenum(VI) and oxovanadium(V) complexes have been reported.
Kar, P
core
Variation in the Biomolecular Interactions of Nickel(Ii) Hydrazone Complexes Upon Tuning the Hydrazide Fragment [PDF]
, 2012 Three new bivalent nickel hydrazone complexes have been synthesised from the reactions of [NiCl2(PPh3)(2)] with H2L {L = dianion of the hydrazones derived from the condensation of o-hydroxynaphthaldehyde with furoic acid hydrazide (H2L1) (1)/thiophene-2 ...
Bhuvanesh, Nattamai S. P. +5 more
core +1 more source
Chemical Syntheses of 3′ and 5′ Phosphorylated Oligonucleotides: An Overview
European Journal of Organic Chemistry, EarlyView.This review provides an overview of the various chemical methods employed in the synthesis of oligonucleotides bearing a phosphate group at their 3′ or 5′ end. Notably, it presents modified phosphoramidites and supports developed for this purpose. Oligonucleotides (ON) with a phosphate monoester group at their 3′ or 5′ end have applications in many ...
Rémy Lartia
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos +4 more
wiley +1 more source
, 2013 Interrelated Two-way Clustering (ITC) is an unsupervised clustering method developed to divide samples into two groups in gene expression data obtained through microarrays, selecting important genes simultaneously in the process.
Basak, Subhash C. +2 more
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü +3 more
wiley +1 more source
Singlet oxygen-mediated one-pot chemoselective peptide–peptide ligation [PDF]
, 2017 We here describe a furan oxidation based site-specific chemical ligation approach using unprotected peptide segments. This approach involves two steps: after photooxidation of a furan-containing peptide, ligation is achieved by reaction of the unmasked ...
Antonatou, Eirini +2 more
core +2 more sources
Macromolecular Rapid Communications, EarlyView.We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh +8 more
wiley +1 more source