Results 141 to 150 of about 2,558 (239)

c‐Met‐Targeted Imaging Agents: Progress and Challenges

open access: yesiRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li   +4 more
wiley   +1 more source

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü   +3 more
wiley   +1 more source

hydrazines

open access: yes, 2014
Citation: 'hydrazines' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02881 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Mono‐ and Bivalent Poly(iso‐butylene)‐Alanines for Drug‐Delivery of Nimodipine and Triamcinolone Acetonide

open access: yesMacromolecular Rapid Communications, EarlyView.
Mono‐ and bivalent‐, alanine‐modified poly‐iso‐butylenes, folding into beta‐sheets, were prepared by living carbocationic polymerization and subsequent endgroup modification. These PIB‐conjugates are useful as solid polymers for the drug release of triamcinolone and nimodipine. ABSTRACT Poly‐iso‐butylene (PIB) is a well known biocompatible polymer with
Philipp S. Hilgeroth   +2 more
wiley   +1 more source

Poly(O‐Propargyl‐N‐Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s

open access: yesMacromolecular Rapid Communications, EarlyView.
We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh   +8 more
wiley   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

open access: yesMacromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Recent advances in Joule‐heating synthesis of functional nanomaterials for photo and electrocatalysis

open access: yesPhotoMat, EarlyView.
This paper presents a comprehensive overview of recent advancements in Joule‐heating synthesis of photo and electrocatalysts, emphasizing its benefits and applications. The objective is to offer an effective strategy for enhancing the diversity and performance of catalytic materials.
Jiaqi Li   +4 more
wiley   +1 more source

Advances in conjugated porous polymers via high internal phase emulsion templating

open access: yesPolymer International, EarlyView.
This mini‐review highlights the design, synthesis and potential applications of π‐conjugated polyHIPEs, emphasizing their unique hierarchical structure and tunable properties. The work outlines innovative synthetic strategies and explores their promising roles in photocatalysis and environmental remediation, paving the way for future advancements in ...
Julie‐Lisa Malaval   +4 more
wiley   +1 more source

HYDRAZINES. [PDF]

open access: yesChemical & Engineering News Archive, 1979
openaire   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

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