Results 31 to 40 of about 8,645 (211)

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Three-Dimensional Hydrazone-Functionalized Covalent Organic Frameworks as pH-Triggered Rotary Switches [PDF]

, 2021
The property expansion of three-dimensional (3D) functionalized covalent organic frameworks (COFs) is important for developing their potential applications.
Wenjuan, Zhao, Fengqian, Chen, Bin, Tang, Yushan, Yan, Chengyang, Yu, Xinyu, Guan, Hui, Li, Valentin, Valtchev, Shilun, Qiu, Qianrong, Fang   +9 more
core   +1 more source

Cytotoxicity and Apoptosis-Induction in MCF-7 Cells for New Pd(II) Complex Based on s-Triazine Ligand: Synthesis, Single Crystal X-ray Diffraction Analysis and Structural Investigations

Crystals, 2023
The synthesis and X-ray structure analysis of the new [PdLCl2]*0.5 CH2Cl2 complex where L is hydrazono-s-triazine di-morpholine derivative, were presented.
Abdulmajeed Abdullah Alayyaf, Assem Barakat, Abdullah Mohammed Al-Majid, M. Ali, Sammer Yousuf, Matti Haukka, Ayman El-Faham, Saied M. Soliman, Mohamed S. Nafie   +8 more
doaj   +1 more source

Ethyl 4-{1-[(2,4-dinitrophenyl)hydrazono]ethyl}-5-(2-naphthylmethoxymethyl)isoxazole-3-carboxylate

Acta Crystallographica Section E, 2009
The title compound, C26H23N5O8, was prepared and its structure investigated to further develop a working hypothesis for the essential binding pharmacophore for ligands of the System Xc- transporter [Patel et al. (2004).
Nicholas R. Natale, Brendan Twamley, Monica I. Szabon-Watola, Richard J. Bridges, Sarjubhai Patel, Trideep Rajale   +5 more
doaj   +1 more source

Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides by a Covalent Catch‐and‐Release Approach

Angewandte Chemie, EarlyView.
A glycan having a hydrazide tag enables chemoenzymatic synthesis of HS oligosaccharides. The hydrazide can, under mild acidic conditions, react with an aldehyde‐containing resin to give an immobilized hydrazone that is stable under neutral conditions, allowing washing. The product can be released by transiminolysis using aqueous hydroxylamine to give a
Francesco Palmieri, Chin Huang, Digantkumar Chapla, Kelley W. Moremen, Geert‐Jan Boons   +4 more
wiley   +2 more sources

Synthesis and antibacterial activity against ralstonia solanacearum for novel hydrazone derivatives containing a pyridine moiety

Chemistry Central Journal, 2012
Background Ralstonia solanacearum, one of the most important bacterial diseases on plants, is a devastating, soil-borne plant pathogen with a global distribution and an unusually wide host range.
Wu Jian, Kang Shenghong, Song Baoan, Hu Deyu, He Ming, Jin Linhong, Yang Song   +6 more
doaj   +1 more source

Hydrazone-Based Amphiphilic Brush Polymer for Fast Endocytosis and ROS-Active Drug Release [PDF]

Due to the high reactivity of reactive oxygen species (ROS), it is essential to sweep them away in time. In this study, ClO–-responsible amphiphilic brush polymers were prepared by free radical polymerization using two monomers consisting of polyethylene
Ruhui Yang (15366532), Yuhan Gao (2563966), Limeng Zhu (12458622), Sicheng Tang (1536586), Shengwu Zheng (15285032), Xingjie Zan (1403275)   +5 more
core   +1 more source

Mechanically Interlocked Indigo Photoswitches

Angewandte Chemie, EarlyView.
By incorporating indigo photoswitches into the axle of a rotaxane, which features a hydrogen bonding macrocycle, we demonstrate improvement in activation wavelength, photostationary states and thermal reversion, an effect that is governed by topologically constrained supramolecular interactions.
Alexander M. Wilmshurst, Taegeun Jo, Rebecca L. Kerridge, Akanksha Ashok Sangolkar, Zhihao Ling, Alex Buchanan, Neil Wells, Yael Ben‐Tal, Stefano Crespi, George T. Williams   +9 more
wiley   +2 more sources

A Comprehensive Review on Analytical Applications of Hydrazone Derivatives

Journal of the Turkish Chemical Society, Section A: Chemistry, 2022
This review covers a summary of analytical applications of hydrazone derivatives in a systematic manner (1961-2021), which will help researchers in the design and development of hydrazone derivatives as potential candidates in medicinal, pharmaceutical ...
Mussarat JABEEN
doaj   +1 more source

Hydrazone-oxime Selectively Directed Redox-Neutral [4 + 2] Annulations Cascade with Alkynes and Iodonium Ylides to Build 1,1′-Biisoquinoline Mono‑N‑oxides [PDF]

Selective C–H activation of a molecule containing multiple directing groups is an important but challenging issue in organic chemistry. Herein, a combined directing group (hydrazone-oxime) selectively directed [4 + 2] annulation cascade to synthesize ...
Jinhua Wang (1506), Shiqing Li (558239), Chaoying Wen (14121487), Yuqin Wang (2382697), Ya-Nan Tian (10148954), Yanyan Yang (412382)   +5 more
core   +1 more source