Results 41 to 50 of about 31,731 (271)

Synthesis, characterisation and antimicrobial activities of vic-dioxime derivatives containing heteroaromatic hydrazone groups and their metal complexes [PDF]

Maejo International Journal of Science and Technology, 2013
Three novel heteroaromatic hydrazone derivatives bearing vic-dioxime groups (L1H2: 5-methyl-2-furfural hydrazone glyoxime, L2H2: 3-acetylpyridine hydrazone glyoxime and L3H2: 4-acetylpyridine hydrazone glyoxime) and their Ni(II), Cu(II) and Co(II ...
Halil Biyik
doaj  

Design, Synthesis and Study of Antibacterial and Antitubercular Activity of Quinoline Hydrazone Hybrids

Heterocyclic Communications, 2020
Emerging bacterial resistance is causing widespread problems for the treatment of various infections. Therefore, the search for antimicrobials is a never-ending task. Hydrazones and quinolines possess a wide variety of biological activities.
T G Shruthi, Subramanian Sangeetha, Eswaran Sumesh   +2 more
doaj   +1 more source

Synthesis and Development of N-2,5-Dimethylphenylthioureido Acid Derivatives as Scaffolds for New Antimicrobial Candidates Targeting Multidrug-Resistant Gram-Positive Pathogens

Antibiotics, 2023
The growing antimicrobial resistance to last-line antimicrobials among Gram-positive pathogens remains a major healthcare emergency worldwide. Therefore, the search for new small molecules targeting multidrug-resistant pathogens remains of great ...
Povilas Kavaliauskas, Birutė Grybaitė, Rita Vaickelionienė, Birutė Sapijanskaitė-Banevič, Kazimieras Anusevičius, Agnė Kriaučiūnaitė, Gabrielė Smailienė, Vidmantas Petraitis, Rūta Petraitienė, Ethan Naing, Andrew Garcia, Vytautas Mickevičius   +11 more
doaj   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

Advanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni, Nitzan Letko Khait, Adam Forman, Edward A. Armstrong, Karim Fouad, Molly S. Shoichet   +5 more
wiley   +1 more source

The interaction of pyridoxal isonicotinoyl hydrazone (PIH) and salicylaldehyde isonicotinoyl hydrazone (SIH) with iron [PDF]

, 2017
The interaction of pyridoxal isonicotinoyl hydrazone (PIH) and salicylaldehyde isonicotinoyl hydrazone (SIH), two important biologically active chelators, with iron has been investigated by spectrophotometric methods.
Hider, Robert C., Yu-Lin Chen, Robert C. Hider, Xie, Yuanyuan, Yuanyuan Xie, Xiaole Kong, Chen, Yu-Lin, Kong, Xiaole   +7 more
core   +1 more source

Clean Grinding Technique: A Facile Synthesis and In Silico Antiviral Activity of Hydrazones, Pyrazoles, and Pyrazines Bearing Thiazole Moiety against SARS-CoV-2 Main Protease (M^pro)

Molecules, 2020
A novel series of some hydrazones bearing thiazole moiety were generated via solvent-drop grinding of thiazole carbohydrazide 2 with various carbonyl compounds.
Sraa Abu-Melha, Mastoura M. Edrees, Sayed M. Riyadh, Mohamad R. Abdelaziz, Abdo A. Elfiky, Sobhi M. Gomha   +5 more
doaj   +1 more source

Synthesis of New Methoxy Actived Mono and Bis-indole Compounds

Hittite Journal of Science and Engineering, 2022
An indole hydrazone has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole-7-carbaldehyde with hydrazine hydrate.
Hakan Kandemir
doaj   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2) [PDF]

, 2019
(NRH):quinone oxidoreductase 2 (NQO2) is associated with various processes involved in cancer initiation and progression probably via the production of ROS during quinone metabolism.
Hussein, Buthaina, Stratford, Ian J., Halbert, Gavin, Freeman, Sally, Kadirvel, Manikandan, Kadirvel, Manikandan; id_orcid, Magwaza, Rachael N., Ikhmais, Balqis, Bryce, Richard A.   +8 more
core   +1 more source

Synthesis of E-Isomer of α-Hydrazone Phosphonates via Nucleophilic Addition of Trialkyl Phosphite to Nitrile Imines (NIs) and DFT Calculations

Journal of Advanced Research in Natural and Applied Sciences
Nitrile imines (NIs) belong to the nitrilium betaine family of 1,3-dipoles. Due to their high reactivity, NI compounds cannot be isolated and must be generated in situ before undergoing the desired transformation.
Sıdıka Polat Çakır, Sinem Altınışık   +1 more
doaj   +1 more source