Results 51 to 60 of about 10,821 (234)
Synthesis of New Methoxy Actived Mono and Bis-indole Compounds
Hittite Journal of Science and Engineering, 2022 An indole hydrazone has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole-7-carbaldehyde with hydrazine hydrate.
Hakan Kandemir
doaj +1 more source
Three-Dimensional Hydrazone-Functionalized Covalent Organic Frameworks as pH-Triggered Rotary Switches [PDF]
, 2021 The property expansion of three-dimensional (3D) functionalized covalent organic frameworks (COFs) is important for developing their potential applications.
Wenjuan, Zhao +9 more
core +3 more sources
Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
Chemistry Proceedings, 2021 The asymmetric hydrazone-thiosemicarbazone ligand H2L was synthesized in two stages by means of a double-condensation reaction. The potentially dianionic and pentadentate [N3SO] organic ligand H2L possesses two flexible bidentate [NS/NO] domains ...
Sandra Fernández-Fariña +4 more
doaj +1 more source
Synthetic route for hydrazone derivatives H1-H5.
, 2021 Synthetic route for hydrazone derivatives H1-H5.
Arlan de Assis Gonsalves (11752026) +13 more
core +1 more source
IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis
Advanced Science, EarlyView.The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui +12 more
wiley +1 more source
Novel DNA Binding Agents: Hydrazone-based Helical Trinuclear Ag Complexes
, 2009 Using the hydrazone linker and the self-assembly, functionalized Ag complexes with a helical structure showed a 2.96 Å distance between metal-metal bonds, well-aligned aromatic rings, and the strong affinity toward DNA ...
鄭建中; Cheng, Chien-chung; Hung, Sue-mei; Yeh, Chia-yi; Chang, Chi-san; 王文竹; Wang, Wen-jwu
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Advanced Science, EarlyView.This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu +10 more
wiley +1 more source
Attainment of Pentagonal-Bipyramidal LnIII Complexes from a Planar Pentadentate Ligand
Proceedings, 2020 The search for mononuclear lanthanoid-based single-ion magnets (SIMs) has increased the interest in some coordination environments with low coordination numbers, in combination with an axial symmetry, as they could maximize the anisotropy of complexes of
Julio Corredoira-Vázquez +3 more
doaj +1 more source