Results 91 to 100 of about 126,036 (251)

Synthesis and Biological Evaluation of Some Novel Thiazole-Based Heterocycles as Potential Anticancer and Antimicrobial Agents

Molecules, 2019
A novel series of thiazole-based heterocycles was synthesized using 1,3-dipolar cycloaddition reactions in the presence of chitosan-grafted-poly(vinylpyridine) as an eco-friendly biopolymeric basic catalyst.
Sraa Abu-Melha, Mastoura M. Edrees, Heba H. Salem, Nabila A. Kheder, Sobhi M. Gomha, Mohamad R. Abdelaziz   +5 more
doaj   +1 more source

A Convenient Ultrasound-Promoted Synthesis of Some New Thiazole Derivatives Bearing a Coumarin Nucleus and Their Cytotoxic Activity

Molecules, 2012
Successful implementation of ultrasound irradiation for the rapid synthesis of a novel series of 3-[1-(4-substituted-5-(aryldiazenyl)thiazol-2-yl)hydrazono)ethyl]-2<em>H</em>-chromen-2-ones<strong> 5a</strong>–<strong>h< ...
Sobhi M. Gomha, Khaled D. Khalil
doaj   +1 more source

Synthesis, Characterization and Docking Study of Novel Pyrimidine Derivatives as Anticancer Agents

Indonesian Journal of Chemistry, 2020
New compounds 5 and 9 using DNA bases e.g. Adenine 1 and Guanine 6 derivatives have been synthesized. The use of simple methods to synthesize compounds 5 and 9 were done using pyrimidine as an alternative DNA base ring.
Manal Mohamed Talaat El-Saidi, Ahmed Ali El-Sayed, Erik Bjerregaard Pedersen, Mohamed Abdelhamid Tantawy, Nadia Ragab Mohamed, Wafaa Ahmed Gad   +5 more
doaj   +1 more source

Reaction of Nitrilimines with 5-Aminotetrazole, 3-Amino-1,2,4-triazole and 3-Amino-5-methylisoxazole [PDF]

, 2013
Reaction of Nitrilimines with 5-Aminotetrazole, 3-Amino-1,2,4-triazole and 3-Amino-5 ...
Al-shayyah, Hussein Talal
core  

Catalytic methods for the synthesis of spirooxindoles, pyrroloindolines, and flavanones [PDF]

, 2016
This thesis discloses catalytic, enantioselective dipolar cycloadditions to deliver new nitrogen-containing heterocycles and formal hydroarylations of olefins that have previously not been possible. Catalytic, enantioselective, dearomative cycloadditions
Gerten, Anthony
core   +3 more sources

Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents

BMC Chemistry, 2019
Pyrazoles, thiazoles and fused thiazoles have been reported to possess many biological activities. 3-Methyl-5-oxo-4-(2-arylhydrazono)-4,5-dihydro-1H-pyrazole-1-carbothioamides 3a,b (obtained from the reaction of ethyl 3-oxo-2-(2-arylhydrazono)butanoates ...
Abdelwahed R. Sayed, Sobhi M. Gomha, Fathy M. Abdelrazek, Mohamed S. Farghaly, Shaimaa A. Hassan, Peter Metz   +5 more
doaj   +1 more source

Trifluoromethylated hydrazones and acylhydrazones as potent nitrogen-containing fluorinated building blocks. [PDF]

Beilstein J Org Chem, 2023
Dongxu Z.
europepmc   +1 more source

Synthesis of Some New Substituted Imidazo (1, 2-a) Pyridines and Their 2-One Derivatives [PDF]

, 2016
2, 3-diaminopyridine (11)(a tri-nitrogen nucleophile) undergoes regioselective cyclocondensation reaction with nitrilimines (2, 10) affording 8-aminoimidazo [1, 2-a] pyridines (12) and 8-aminoimidazo [1, 2-a] pyridine-2-ones (13), respectively.
Abu Thaher, Bassam A.
core  

Aspects of the chemistry of some highly crowded aromatic ligands [PDF]

, 1990
A series of ortho-substituted arylchlorophosphoranes has been prepared. The structures of these compounds have been studied by the use of (^31)Cl n.q.r. and solid-state (^31)P n.m.r. . It has been shown that ortho substitution by groups such as CH(_3) or
Straw, T. A.
core  

Asymmetric 1,3-dipolar cycloadditions of acrylamides [PDF]

, 2009
This critical review, which is relevant to researchers in synthetic organic chemistry, focuses on asymmetric 1,3-dipolar cycloadditions with acrylamides.
Kissane, Marie, Maguire, Anita R.
core   +1 more source