Results 101 to 110 of about 562 (194)

Synthesis of Heteroaromatic Compounds. [PDF]

Molecules, 2023
Sloop J.
europepmc   +1 more source

Novel imidazoles from guanylhydrazone: Synthesis, computational, and molecular docking studies as α-amylase inhibitors for type 2 diabetes management

Results in Chemistry
This study reports a facile synthesis of novel imidazole derivatives as potential α-amylase inhibitors for type 2 diabetes management. Starting with readily available precursors (p-chloroacetophenone and aminoguanidine), guanylhydrazone 3 was synthesized
Mohamed G. Badrey, Ahmed A. Elhenawy, Mohammad Mahboob Alam, Syed Nazreen, Magdi E.A. Zaki, Sobhi M. Gomha   +5 more
doaj   +1 more source

Synthesis and functionalization of a lactam-pyrazole molecular scaffold as a promising anticancer compound [PDF]

, 2015
The importance of pyrazole and lactam-based molecules in medical and pharmaceutical fields is underlined by the multitude of active ingredients on trade, such as Sildenafil or Apixaban, by Pfizer.
Bertuzzi, Giulio
core  

Synthesis, characterization, and in silico studies of substituted 2,3-dihydro-1,3,4-thiadiazole derivatives

Results in Chemistry
The reaction of hydrazonoyl halides with different carbodithioate derivatives in the presence of triethylamine was studied, resulting in the synthesis of a series of unsymmetrical azine derivatives with yields ranging from 64 % to 80 %. The structures of
Yasser H. Zaki, Sobhi M. Gomha, Basant Farag, Magdi E.A. Zaki, Ahmed M. Hussein   +4 more
doaj   +1 more source

Graphical Contents

, 2014
Graphical ...
Arslan, Hakan
core   +1 more source

Anti-proliferate Activity and 5α-reductase Inhibitors of Chiral Macrocyclic (Nα-di-nicotinoyl)[L-phenylalaninyl-L-leucinyl]Pentapeptide Candidates Against LNCaP and PC-3 Prostate Cancer Cell Lines [PDF]

, 2020
60-65A series of macrocyclic derivatives 2-6 were prepared using Nα-dinicotinoyl-bis[L-phenylalaninyl-L-leucyl]hydrazide 1 and cyclo pentapeptide hydrazide 2 as starting materials.
Alanazi, M M, Amr, M A E, Elsayed, E A, Mageid, R E Abdel, Naglah, A M   +4 more
core  

[3+2]-Cycloaddition of Nitrile Imines to Parabanic Acid Derivatives-An Approach to Novel Spiroimidazolidinediones. [PDF]

Int J Mol Sci, 2023
Kuznetsova JV, Tkachenko VT, Petrovskaya LM, Filkina ME, Shybanov DE, Grishin YK, Roznyatovsky VA, Tafeenko VA, Pestretsova AS, Yakovleva VA, Pokrovsky VS, Kukushkin ME, Beloglazkina EK.   +12 more
europepmc   +1 more source

Cyanauric Chloride as a key precursor and a core component for Three-Armed Triazolopyrimidines: Recent finding about SARs and docking analyses

Results in Chemistry
The s-triazine trichloride is a reactive compound and can be used as key intermediate for delivering polysubstituted triazines specially the three-armed ones.
Mohamed G. Badrey, Sobhi M. Gomha, Magdi E.A. Zaki, Basant Farag, Ahmed A.M. El-Reedy   +4 more
doaj   +1 more source

Synthesis and antimicrobial activity of new series of thiazoles, pyridines and pyrazoles based on coumarin moiety. [PDF]

Sci Rep, 2023
Sayed MT, Elsharabasy SA, Abdel-Aziem A.
europepmc   +1 more source

One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents

Drug Design, Development and Therapy, 2020
Abdelwahed R Sayed,1,2 Sobhi M Gomha,3,4 Eman A Taher,5,6 Zeinab A Muhammad,5 Hesham R El-Seedi,6,7 Hatem M Gaber,5 Mahgoub M Ahmed8 1Department of Chemistry, Faculty of Science, KFU, Hofuf, Saudi Arabia; 2Department of Chemistry, Faculty of Science ...
Sayed AR, Gomha SM, Taher EA, Muhammad ZA, El-Seedi HR, Gaber HM, Ahmed MM   +6 more
doaj