Computer assisted synthesis and in-vitro cytotoxic evaluation of new pyrazole-fused isoquinolinoquinones derivatives as PI3K receptor antagonist with promising antitumoral activity [PDF]
, 2016 The importance of pyrazole and isoquinoline-5,8-dione scaffolds in medical chemistry is underlined by the high number of drugs currently on trading that contains these active ingredients.
Crotti, Simone
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Exocyclic enaminones as building blocks for synthesis of bioactive polyheterocyclic compounds [PDF]
, 2014 The reaction of exocyclic enaminones namely, 2-(dimethylaminomethylene)-3,4-dihydro-2H-naphthalen-1-one, 3-(dimethylaminomethylene)-thiochroman-4-one and 2-(dimethyl-aminomethylene)-indane-1,3-dione, each with heterocyclic diazonium salts afforded the ...
Abdallah, Magda A. +2 more
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A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation [PDF]
, 2019 Brain tumor, as any type of cancer, is assumed to be sustained by a small subpopulation of stem-like cells with distinctive properties that allow them to survive conventional therapies and drive tumor recurrence. Thus, the identification of new molecules
Cecília M. P. Rodrigues +4 more
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A convenient synthesis of 5-amino-4-(2-benzothiazolyl)pyrazoles [PDF]
, 1997 1175 ...
Abdallah, Magda A +3 more
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Reactions with Hydrazonoyl Halides. Part XXV.1 Synthesis of Some New 2,3-Dihydro-1,3,4-thiadiazoles and 5-Arylazothiazoles [PDF]
, 1999 Abdou O. Abdelhamid +2 more
openalex +1 more source
[3+2]-Cycloaddition of Nitrile Imines to Parabanic Acid Derivatives-An Approach to Novel Spiroimidazolidinediones. [PDF]
Int J Mol Sci, 2023 Kuznetsova JV +12 more
europepmc +1 more source
Synthesis and antimicrobial activity of new series of thiazoles, pyridines and pyrazoles based on coumarin moiety. [PDF]
Sci Rep, 2023 Sayed MT, Elsharabasy SA, Abdel-Aziem A.
europepmc +1 more source
Synthesis and functionalization of a lactam-pyrazole molecular scaffold as a promising anticancer compound [PDF]
, 2015 The importance of pyrazole and lactam-based molecules in medical and pharmaceutical fields is underlined by the multitude of active ingredients on trade, such as Sildenafil or Apixaban, by Pfizer.
Bertuzzi, Giulio
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