Results 51 to 60 of about 562 (194)

Synthesis and Antimicrobial Activity of Some New Pyrazoles, Fused Pyrazolo[3,4-d]-pyrimidine and 1,2-Dihydroimidazo-[2,1-c][1,2,4]triazin-6-one Derivatives

open access: yesMolecules, 2011
A novel series of 7,7-diphenyl-1,2-dihydroimidazo[2,1-c][1,2,4]triazin-6(7H)-one 6a–h, were easily prepared via reactions of novel 2-hydrazinyl-4,4-diphenyl-1H-imidazol-5(4H)-one (2) with hydrazonoyl halides 3a–h.
Huwaida M.E. Hassaneen   +1 more
doaj   +1 more source

Synthesis and tautomerism of aryl- and hetaryl-azo derivatives of bi- and tri-heterocycles

open access: yesJournal of Advanced Research, 2010
This review summarizes results from the literature concerning synthesis and azo-hydrazone tautomerism of arylazo- and hetarylazo-derivatives of various bi- and tri-heterocycles reported by us and other research groups from 1981 to mid 2009.
Ahmad S. Shawali
doaj   +1 more source

Reactions with hydrazonoyl halides 66: Synthesis of some new 1,3,4-thiadiazoles, triazolino[4,3-a]pyrimidines and isoxazolo[3,4-d]pyridazines containing coumarin moiety [PDF]

open access: yes, 2011
2,3-Dihydro-1,3,4-thiadiazoles, triazolino[4,3-a]pyrimidines, isoxazoles and isoxazolo[3,4-d]pyridazines containing coumarin moities were synthesized from the reactions of methyl (or benzyl) carbodithioate, pyrimidine-2-thione and 3-(3-(dimethylamino ...
Abdelhamid, Abdou Osman   +2 more
core   +1 more source

Synthesis and Antibacterial Activity of New Spiro[thiadiazoline‐(pyrazolo[3,4‐d]pyrimidine)] Derivatives

open access: yesJournal of Chemistry, Volume 2015, Issue 1, 2015., 2015
New heterocyclic compounds spiroderivatives of allopurinol of biological interest were prepared from allopurinol via thionation and 1,3‐dipolar cycloaddition and were produced in high to excellent yields. These compounds were characterized on the basis of spectral and spectroscopic data (1H NMR, 13C, IR, and MS).
Mohammed El Fal   +6 more
wiley   +1 more source

1,3,4-Thiadiazoles of pharmacological interest: Recent trends in their synthesis via tandem 1,3-dipolar cycloaddition: Review

open access: yesJournal of Advanced Research, 2014
This review article presents a survey of the utility of a new synthetic strategy for 1,3,4-thiadiazole derivatives based on reactions of nitrilimines with various functionalized sulfur dipolarophiles which proceed via tandem in situ 1,3-dipolar ...
Ahmad S. Shawali
doaj   +1 more source

Synthesis, Molecular Docking Study, and Cytotoxic Activity against MCF Cells of New Thiazole–Thiophene Scaffolds

open access: yesMolecules, 2022
Investigating novel compounds that may be useful in designing new, less toxic, selective, and potent breast anticancer agents is still the main challenge for medicinal chemists.
Sobhi M. Gomha   +4 more
doaj   +1 more source

Regioselective synthesis of some functionalized 3,4’-bis-(pyrazolyl)ketones and chemoselectivity in their reaction with hydrazine hydrate

open access: yes, 2013
A new enamino ester, (E)-ethyl 3-(dipropylamino)acrylate, was prepared and used for synthesis of various pyrazole derivatives, 4a-k and 5a-d. Other new enaminone, (E)-ethyl 3-(3-(dimethylamino)acryloyl)-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate (8 ...
Hassaneen, Hamdi Mahmoud   +1 more
core   +1 more source

Fused Imidazopyrazoles: Synthetic Strategies and Medicinal Applications

open access: yesJournal of Chemistry, Volume 2014, Issue 1, 2014., 2014
The current review summarizes the known synthetic routes of fused imidazopyrazoles. This review is classified into two main categories based on the type of annulations, for example, annulation of the imidazole ring onto a pyrazole scaffold or annulation of the pyrazole ring onto an imidazole scaffold. Some medicinal applications of imidazopyrazoles are
Rizk E. Khidre   +3 more
wiley   +1 more source

Reactions with Hydrazonoyl Halides. 31. Synthesis of Some New Pyrrolidino[3,4-c]pyrazolines, Pyrazoles, and Pyrazolo[3,4-d]pyridazines

open access: yesMolecules, 2000
Pyrrolidino[3,4-c]pyrazoline and pyrazole derivatives were synthesized via reactions of a substituted hydrazonoyl bromide with N-arylmaleimides and active methylene reagents, respectively. Synthesized pyrazoles were reacted with hydrazine hydrate to give
Nagla A. Ahmed   +3 more
doaj   +1 more source

Benzo[1,5]thiazepine: Synthesis, Reactions, Spectroscopy, and Applications

open access: yesOrganic Chemistry International, Volume 2013, Issue 1, 2013., 2013
This review article deals with synthesis and reactions of benzo[1,5]thiazepines and the related derivatives and their applications, biological activity as well as spectroscopic data. Most of the reported data on the methods of synthesis, chemical reactions, and biological activity of these heterocycles published over the last ten years are reviewed in ...
Khairy A. M. El-Bayouki, William Setzer
wiley   +1 more source

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