Results 51 to 60 of about 126,036 (251)

Ultrasound-assisted green synthesis and antimicrobial assessment of 1,3-thiazoles and 1,3,4-thiadiazines

Green Chemistry Letters and Reviews, 2021
In this article, we applied ultrasonic irradiation as an ecofriendly, green, efficient approach for the synthesis of a new 1,3-thiazoles and 1,3,4-thiadiazines under solvent-free conditions.
Sara N. Shabaan, Basma Saad Baaiu, Anhar Abdel-Aziem, Mohamed S. Abdel-Aziz   +3 more
doaj   +1 more source

Novel thiadiazole-thiazole hybrids: synthesis, molecular docking, and cytotoxicity evaluation against liver cancer cell lines

Journal of Taibah University for Science, 2022
One of the worst diseases, cancer claims millions of lives each year throughout the world, necessitating the creation of novel treatments. In this study, we designed a novel series of 1,3,4-thiadiazoles through the reaction of 2-(4-methyl-2-(2-(1 ...
Ghadah F. Aljohani, Tariq Z. Abolibda, Mohammad Alhilal, Jehan Y. Al-Humaidi, Suzan Alhilal, Hoda A. Ahmed, Sobhi M. Gomha   +6 more
doaj   +1 more source

Reaction of nitrilimines and nitrile oxides with hydrazines, hydrazones and oximes [PDF]

, 2005
This review article discusses the reaction of nitrilimines and nitrile oxides with hydrazines, hydrazones, and oximes. Three reaction modes were observed.
Awadallah, Adel M., Ferwanah, Abdel-Rahman S.   +1 more
core   +2 more sources

A new convenient synthesis of 3-hetaryl-pyrazolo[5,1-c][1,2,4]triazines

Journal of Advanced Research, 2012
Reactions of enaminones 2 with diazotized 5-amino-3-phenylpyrazole provide a convenient route to 3-[(4,5-disubstituted-pyrazol-3-yl)carbonyl]-pyrazolo[5,1-c][1,2,4]triazines.
Ahmad S. Shawali
doaj   +1 more source

Synthesis and Antimicrobial Activity of Some New Thiadiazoles, Thioamides, 5-Arylazothiazoles and Pyrimido[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines

Molecules, 2016
A novel series of 1,3,4-thiadiazoles, 5-arylazothiazoles and hexahydropyrimido-[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines were synthesized via reaction of hydrazonoyl halides with each of alkyl carbothioates, carbothioamides and 7-thioxo-5,6,7,8 ...
Abdou O. Abdelhamid, Ibrahim E. El Sayed, Mohamed Z. Hussein, Mangoud M. Mangoud   +3 more
doaj   +1 more source

Synthesis and Cytotoxicity Evaluation of Some Novel Thiazoles, Thiadiazoles, and Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones Incorporating Triazole Moiety

Molecules, 2015
Reactions of hydrazonoyl halides and each of methyl 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazine-1-carbodithioate and 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazine-1-carbothioamide afforded 2-(1-(5-methyl-1 ...
Sobhi M. Gomha, Sayed A. Ahmed, Abdou O. Abdelhamid   +2 more
doaj   +1 more source

Synthesis and Antimicrobial Studies of Some Novel Bis-[1,3,4]thiadiazole and Bis-thiazole Pendant to Thieno[2,3-b]thiophene Moiety [PDF]

, 2012
The synthetic utility of 3,3′-(3,4-dimethylthieno[2,3-b]thiophene-2,5-diyl)bis (3-oxopropanenitrile) (1) in the synthesis of some novel bis-[1,3,4-thiadiazole] 6a–g and bis-thiazole 10 and 13 derivatives with thieno[2,3-b]thiophene moiety is reported ...
Kheder, Nabila Abdelshafy, Mabkhot, Yahia Nasser   +1 more
core   +3 more sources

Chemistry of the Enaminone of 1-Acetylnaphthalene under Microwave Irradiation Using Chitosan as a Green Catalyst

Molecules, 2011
Enaminone 1 was reacted with hydrazonoyl halides 2a-d to yield 3,4-disubstituted pyrazoles 6a-d. Coupling with arenediazonium chlorides afforded the 2-(arylhydrazono)-3-(1-naphthalenyl)-3-oxopropionaldehydes 13a-c.
Huwaida M. E. Hassaneen
doaj   +1 more source

Synthesis and Antibacterial Activity of New Spiro[thiadiazoline‐(pyrazolo[3,4‐d]pyrimidine)] Derivatives

Journal of Chemistry, Volume 2015, Issue 1, 2015., 2015
New heterocyclic compounds spiroderivatives of allopurinol of biological interest were prepared from allopurinol via thionation and 1,3‐dipolar cycloaddition and were produced in high to excellent yields. These compounds were characterized on the basis of spectral and spectroscopic data (1H NMR, 13C, IR, and MS).
Mohammed El Fal, Youssef Ramli, Abdelfettah Zerzouf, Ahmed Talbaoui, Youssef Bakri, El Mokhtar Essassi, Marco Radi   +6 more
wiley   +1 more source

Synthesis and Antimicrobial Activity of Some New Pyrazoles, Fused Pyrazolo[3,4-d]-pyrimidine and 1,2-Dihydroimidazo-[2,1-c][1,2,4]triazin-6-one Derivatives

Molecules, 2011
A novel series of 7,7-diphenyl-1,2-dihydroimidazo[2,1-c][1,2,4]triazin-6(7H)-one 6a–h, were easily prepared via reactions of novel 2-hydrazinyl-4,4-diphenyl-1H-imidazol-5(4H)-one (2) with hydrazonoyl halides 3a–h.
Huwaida M.E. Hassaneen, Sobhi Mohamed Gomha   +1 more
doaj   +1 more source