Results 81 to 90 of about 562 (194)

Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study

Drug Design, Development and Therapy, 2021
Sobhi M Gomha,1,2 Hyam A Abdelhady,2 Doaa ZH Hassain,2 Aboubakr H Abdelmonsef,3 Mohamed El-Naggar,4 Mahmoud M Elaasser,5 Huda K Mahmoud2 1Chemistry Department, Faculty of Science, Islamic University in Almadinah Almonawara, Almadinah Almonawara, 42351 ...
Gomha SM, Abdelhady HA, Hassain DZH, Abdelmonsef AH, El-Naggar M, Elaasser MM, Mahmoud HK   +6 more
doaj  

HETEROCYCLIC SYNTHESIS USING NITRILIMINES: PART 18. SYNTHESIS OF NEW FUSED HETEROCYCLES CONTAINING TRIAZINONE MOIETY [PDF]

, 2011
A series of new 4,5-dihydro-6-oxo-1,2,4-triazino[4,5-b]1,2,3,4-tetrahydro-β-carbolines were synthesized by the reaction of methyl 1,2,3,4-tetrahydro-β-carboline-3-carboxylate and the appropriate hydrazonoyl halide in presence of triethylamine.
Dalloul, Hany Mahmod
core   +1 more source

Synthesis of New Series of Pyrazoline, and Study their Kinetics and Reaction Mechanism [PDF]

, 2019
A new series of novel pyrazoline compounds were synthesized by addition of thiosemicarbazide to the 2,6-dibenzylidenecyclohexanone (Chalcone) and its para substituted derivatives. This study was conducted for four purposes.
Hamad, Wali M., Ibrahim, Aram H., Kaka, Kosrat N., Taher, Salam G.   +3 more
core   +2 more sources

Synthesis and Biological Evaluation of Some Novel Thiazole-Based Heterocycles as Potential Anticancer and Antimicrobial Agents

Molecules, 2019
A novel series of thiazole-based heterocycles was synthesized using 1,3-dipolar cycloaddition reactions in the presence of chitosan-grafted-poly(vinylpyridine) as an eco-friendly biopolymeric basic catalyst.
Sraa Abu-Melha, Mastoura M. Edrees, Heba H. Salem, Nabila A. Kheder, Sobhi M. Gomha, Mohamad R. Abdelaziz   +5 more
doaj   +1 more source

A Convenient Ultrasound-Promoted Synthesis of Some New Thiazole Derivatives Bearing a Coumarin Nucleus and Their Cytotoxic Activity

Molecules, 2012
Successful implementation of ultrasound irradiation for the rapid synthesis of a novel series of 3-[1-(4-substituted-5-(aryldiazenyl)thiazol-2-yl)hydrazono)ethyl]-2<em>H</em>-chromen-2-ones<strong> 5a</strong>–<strong>h< ...
Sobhi M. Gomha, Khaled D. Khalil
doaj   +1 more source

Reactions with hydrazonoyl halides: Part XVIII-Synthesis of pyrrolidino[3,4-c] pyrazole, pyrazolo[3,4-d]pyridazine, imidazo-[1,2-a ]pyridine, pyrazolo[3,4-d]pyrimidine and other heterocyclic derivatives [PDF]

, 1997
880 ...
Abdelhamid, Abdou O, Emam, Hussein A
core  

Reaction of Nitrilimines with 5-Aminotetrazole, 3-Amino-1,2,4-triazole and 3-Amino-5-methylisoxazole [PDF]

, 2013
Reaction of Nitrilimines with 5-Aminotetrazole, 3-Amino-1,2,4-triazole and 3-Amino-5 ...
Al-shayyah, Hussein Talal
core  

Asymmetric 1,3-dipolar cycloadditions of acrylamides [PDF]

, 2009
This critical review, which is relevant to researchers in synthetic organic chemistry, focuses on asymmetric 1,3-dipolar cycloadditions with acrylamides.
Kissane, Marie, Maguire, Anita R.
core   +1 more source

Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents

BMC Chemistry, 2019
Pyrazoles, thiazoles and fused thiazoles have been reported to possess many biological activities. 3-Methyl-5-oxo-4-(2-arylhydrazono)-4,5-dihydro-1H-pyrazole-1-carbothioamides 3a,b (obtained from the reaction of ethyl 3-oxo-2-(2-arylhydrazono)butanoates ...
Abdelwahed R. Sayed, Sobhi M. Gomha, Fathy M. Abdelrazek, Mohamed S. Farghaly, Shaimaa A. Hassan, Peter Metz   +5 more
doaj   +1 more source

Synthesis of Some New Substituted Imidazo (1, 2-a) Pyridines and Their 2-One Derivatives [PDF]

, 2016
2, 3-diaminopyridine (11)(a tri-nitrogen nucleophile) undergoes regioselective cyclocondensation reaction with nitrilimines (2, 10) affording 8-aminoimidazo [1, 2-a] pyridines (12) and 8-aminoimidazo [1, 2-a] pyridine-2-ones (13), respectively.
Abu Thaher, Bassam A.
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