Results 81 to 90 of about 126,036 (251)
Results in Chemistry, 2023 The essential enzyme cyclin-dependent kinase 2 (CDK2) is a promising target for anticancer drug development due to its pivotal role in regulating the cell cycle. This study aimed to synthesize novel 3-thiazolyl-indole derivatives and assess their ability
Sobhi M. Gomha +6 more
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Molecules, 2018 The one-pot synthesis of a series of pyrazoline derivatives containing the bioactive thiazole ring has been performed through a 1,3-dipolar cycloaddition reaction of N-thiocarbamoylpyrazoline and different hydrazonoyl halides or α-haloketones in the
Mastoura M. Edrees +5 more
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Synthesis of 5-arylazothiazoles, pyridines and thieno[2,3-b]pyridines derivatives containing 1,2,3-triazole moiety [PDF]
, 2012 1-(2-(4,5-dihydro-3-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-5-phenylpyrazol-1-yl)-4-subs-tituted-thiazol-5-yl)-2-phenyldiazene (4) and substituted pyridines (5-12) were synthesized via reaction of 1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-3 ...
Abdel-Riheem, Nadia Abdelhamid +3 more
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HETEROCYCLIC SYNTHESIS USING NITRILIMINES: PART 18. SYNTHESIS OF NEW FUSED HETEROCYCLES CONTAINING TRIAZINONE MOIETY [PDF]
, 2011 A series of new 4,5-dihydro-6-oxo-1,2,4-triazino[4,5-b]1,2,3,4-tetrahydro-β-carbolines were synthesized by the reaction of methyl 1,2,3,4-tetrahydro-β-carboline-3-carboxylate and the appropriate hydrazonoyl halide in presence of triethylamine.
Dalloul, Hany Mahmod
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Advances in chemical protein modification. [PDF]
, 2015 Chemical protein modification has emerged as an invaluable tool for the development of modified proteins. The complementary use of both genetic and chemical methods has provided a large toolbox that allows the preparation of almost unlimited protein ...
Bernardes, Gonçalo JL, Boutureira, Omar
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Molecules, 2003 2-Thioxopyrimidinyl-5-(N,N-dimethylamino)formamidine (5) and 1,3-diphenyltriazolo[3,4-d]pyrimidinyl-N,N-dimethylformamidine (14) were prepared by condensation of 6-amino-2-thioxo-1,3-dihydropyrimidin-4-one (2) and 7-amino-1,3-diphenyl-1,2,4-triazolo[4,3 ...
Tayseer A. Abdallah, Hamdi M. Hassneen
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Synthesis of New Series of Pyrazoline, and Study their Kinetics and Reaction Mechanism [PDF]
, 2019 A new series of novel pyrazoline compounds were synthesized by addition of thiosemicarbazide to the 2,6-dibenzylidenecyclohexanone (Chalcone) and its para substituted derivatives. This study was conducted for four purposes.
Hamad, Wali M. +3 more
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Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles
Molecules, 2017 A series of new morpholinylchalcones was prepared and then used as building blocks for constructing a series of 7-morpholino-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones via their reaction with 6-aminothiouracil.
Zeinab A. Muhammad +5 more
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HETEROCYCLIC SYNTHESIS USING NITRILIMINES: PART 8†. SYNTHESIS OF AROMATIC 1,2,4-TRIAZOLES [PDF]
, 2008 A series of new 1,2,4-triazole derivatives (6a-p) have been synthesized by the reaction of amidines 3 with certain nitrilimines 2. The structures of newly synthesized compounds are confirmed by their analytical and spectral data including IR and NMR. Key
Abu Samahab, Ahmed S. +2 more
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Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study
Drug Design, Development and Therapy, 2021 Sobhi M Gomha,1,2 Hyam A Abdelhady,2 Doaa ZH Hassain,2 Aboubakr H Abdelmonsef,3 Mohamed El-Naggar,4 Mahmoud M Elaasser,5 Huda K Mahmoud2 1Chemistry Department, Faculty of Science, Islamic University in Almadinah Almonawara, Almadinah Almonawara, 42351 ...
Gomha SM +6 more
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