Studies on the subunit structure of 4-deoxy-5-oxoglucarate hydro-lyase (decarboxylating) from Pseudomonas acidovorans [PDF]
Biochemical Journal, 1975 1. Homogeneous preparations of D-4-deoxy-5-oxoglutarate hydro lyase (decarboxylating)(EC4.2.1.41) were analysed in the ultracentrifuge by the high-speed sedimentation-equilibrium method of Yphantis (1964). The molecular weight in 0.1 M-potassium phosphate buffer, pH 7.2, in 6M-guanidine hydrochloride and in 0.1 M-beta-mercaptoethanol in 6M-guanidine ...
R Jeffcoat
openaire +4 more sources
Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics. [PDF]
Microb BiotechnolThis study explores the metabolic potential of Lentilactobacillus hilgardii for malolactic fermentation in winemaking. Genomic and in silico analyses, combined with experimental validation, reveal its resilience at low temperatures and unique enzymatic traits. Comparative insights with Oenococcus oeni highlight L.
Mantegazza G +5 more
europepmc +2 more sources
Oxidative Inactivation of Mitochondrial Aconitase Results in Iron and H2O2-Mediated Neurotoxicity in Rat Primary Mesencephalic Cultures [PDF]
, 2009 BACKGROUND:Mitochondrial oxidative stress is a contributing factor in the etiology of numerous neuronal disorders. However, the precise mechanism(s) by which mitochondrial reactive oxygen species (ROS) modify cellular targets to induce the death of ...
A Boveris +48 more
core +11 more sources
Relating the metatranscriptome and metagenome of the human gut [PDF]
, 2014 Although the composition of the human microbiome is now wellstudied, the microbiota’s \u3e8 million genes and their regulation remain largely uncharacterized.
Boylan, Matthew R. +13 more
core +2 more sources
Expanding the synthetic scope of biocatalysis by enzyme discovery and protein engineering [PDF]
, 2021 This paper is dedicated to the memory of Jon Williams who was a pioneer of chemo-enzymatic catalysis, a field which has grown significantly thanks to his vision and ideas.Despite the growing impact of enzyme catalysis in industrial chemistry, the full ...
Mangas-Sanchez, Juan +2 more
core +2 more sources
Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina [PDF]
, 2011 Two carotenoid 1,2-hydratase (CrtC) genes from the photosynthetic bacteria Rubrivivax gelatinosus and Thiocapsa roseopersicina were cloned and expressed in Escherichia coli in an active form and purified by affinity chromatography.
A Wanikawa +27 more
core +2 more sources
Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty [PDF]
, 1971 Recent experimental information on DNA sequence repetition is reviewed, and the significance of both repetitive and non-repetitive sequence considered.
Britten, Roy J., Davidson, Eric H.
core +1 more source
Endocytic iron trafficking and mitochondria in Parkinson's disease [PDF]
, 2019 Parkinson's disease (PD) - the second most common neurodegenerative disorder - is a multifactorial disease, the causes of which should be sought in complex and detrimental interactions between genetic and environmental factors. Multiple lines of evidence,
Cerri S. +2 more
core +5 more sources
ThYme: a database for thioester-active enzymes [PDF]
, 2010 The ThYme (Thioester-active enzYme; http://www.enzyme.cbirc.iastate.edu) database has been constructed to bring together amino acid sequences and 3D (tertiary) structures of all the enzymes constituting the fatty acid synthesis and polyketide synthesis ...
Berman +12 more
core +4 more sources
Inactivation of Aconitase by Tetrahydrobiopterin in DArgic Cells: Relevance to PD [PDF]
, 2010 Oxidative damage is thought to be a major cause of the progression of dopamine (DA)rgic neurodegeneration as in Parkinson's disease. We have previously reported that tetrahydrobiopterin (BH4), an endogenous molecule required for DA synthesis, exerts ...
Berman +26 more
core +2 more sources