Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics. [PDF]
This study explores the metabolic potential of Lentilactobacillus hilgardii for malolactic fermentation in winemaking. Genomic and in silico analyses, combined with experimental validation, reveal its resilience at low temperatures and unique enzymatic traits. Comparative insights with Oenococcus oeni highlight L.
Mantegazza G +5 more
europepmc +2 more sources
Expanding the synthetic scope of biocatalysis by enzyme discovery and protein engineering [PDF]
This paper is dedicated to the memory of Jon Williams who was a pioneer of chemo-enzymatic catalysis, a field which has grown significantly thanks to his vision and ideas.Despite the growing impact of enzyme catalysis in industrial chemistry, the full ...
Mangas-Sanchez, Juan +2 more
core +2 more sources
Mitochondrial respiratory chain and Krebs cycle enzyme function in human donor livers subjected to end-ischaemic hypothermic machine perfusion [PDF]
INTRODUCTION: Marginal human donor livers are highly susceptible to ischaemia reperfusion injury and mitochondrial dysfunction. Oxygenation during hypothermic machine perfusion (HMP) was proposed to protect the mitochondria but the mechanism is unclear ...
Abudhaise, H +4 more
core +1 more source
Endocytic iron trafficking and mitochondria in Parkinson's disease [PDF]
Parkinson's disease (PD) - the second most common neurodegenerative disorder - is a multifactorial disease, the causes of which should be sought in complex and detrimental interactions between genetic and environmental factors. Multiple lines of evidence,
Cerri S. +2 more
core +5 more sources
Relating the metatranscriptome and metagenome of the human gut [PDF]
Although the composition of the human microbiome is now wellstudied, the microbiota’s \u3e8 million genes and their regulation remain largely uncharacterized.
Boylan, Matthew R. +13 more
core +2 more sources
Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty [PDF]
Recent experimental information on DNA sequence repetition is reviewed, and the significance of both repetitive and non-repetitive sequence considered.
Britten, Roy J., Davidson, Eric H.
core +1 more source
Characterization of C-nucleoside Antimicrobials from Streptomyces albus DSM 40763: Strepturidin is Pseudouridimycin [PDF]
Pseudouridimycin (PUM), a selective inhibitor of bacterial RNA polymerase has been previously detected in microbial-extracts of two strains of Streptomyces species (strain ID38640 and ID38673).
Belogurov GA +7 more
core +1 more source
Metabolic recovery of Arabidopsis thaliana roots following cessation of oxidative stress [PDF]
To cope with the various environmental stresses resulting in reactive oxygen species (ROS) production plant metabolism is known to be altered specifically under different stresses.
Fernie, A. +4 more
core +3 more sources
The transcriptional regulator TamR from Streptomyces coelicolor controls a key step in central metabolism during oxidative stress [PDF]
Summary: Multiple antibiotic resistance regulator (MarR) family transcriptional regulators usually regulate gene activity by responding to specific ligands.
Grove, Anne, Huang, Hao
core +2 more sources
Gyrase Inhibitors Induce an Oxidative Damage Cellular Death Pathway in Escherichia Coli [PDF]
Modulation of bacterial chromosomal supercoiling is a function of DNA gyrase-catalyzed strand breakage and rejoining. This reaction is exploited by both antibiotic and proteic gyrase inhibitors, which trap the gyrase molecule at the DNA cleavage stage ...
Daniel J Dwyer +11 more
core +2 more sources

