Results 31 to 40 of about 2,340 (183)

Use of LC‐MS to characterize host cell protein removal during depth filtration

Biotechnology Progress, Volume 41, Issue 5, September/October 2025.
Abstract The removal of host cell proteins (HCPs) is crucial in biopharmaceutical production, as residual impurities can impact product safety and efficacy. While a number of studies have demonstrated that depth filtration can provide significant HCP removal, there is little information on its effectiveness in removing specific HCPs.
Liang‐Kai Chu, Ehsan Espah Borujeni, Xuankuo Xu, Andrew L. Zydney   +3 more
wiley   +1 more source

A census analysis of the 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase and EPSP-associated domains [PDF]

, 2020
Glyphosate is one of the most used herbicides against weeds that targets the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). EPSPS is the central enzyme in the shikimate pathway to synthesize 3 essential amino acids in plants, fungi, and ...
Tall, Tuomas
core  

Mitochondrial Oxidative Stress and Calcium-Dependent Permeability Transition are Key Players in the Mechanisms of Statins-Associated Side Effects [PDF]

, 2017
Statins are cholesterol-lowering medicines utilized worldwide and are associated with reduced risk of cardiovascular mortality and events. However, 0.5–10% of patients suffer from adverse effects especially on skeletal muscle.
Busanello, Estela N.B., de Oliveira, Helena C.F., Lorza-Gil, Estela, Marques, Ana C., Vercesi, Anibal E.   +4 more
core   +2 more sources

Production and scavenging of reactive oxygen species in plant cells under cadmium stress

Agronomy Journal, Volume 117, Issue 4, July/August 2025.
Abstract Cadmium (Cd) causes the excessive accumulation of reactive oxygen species (ROS) in plant cells, inhibits plant growth, and reduces crop productivity (e.g., grain yields). However, our understanding of Cd migration, ROS accumulation, and the underlying mechanisms in plant cells remains limited.
Ying Hu, Huichun Wang
wiley   +1 more source

COMPARATIVE APPROACHES FOR PLANT GENOMES: UNRAVELING "INTRA" AND "INTER" SPECIES RELATIONSHIPS FROM PRELIMINARY GENE ANNOTATIONS [PDF]

, 2016
Comparative genomics studies the differences and similarities between different species, to transfer biological information from model organisms to newly sequenced genomes, and to understand the evolutionary forces that drive changes in genomic features ...
Ambrosino, Luca
core  

Quantitative comparison of catalytic mechanisms and overall reactions in convergently evolved enzymes : implications for classification of enzyme function [PDF]

, 2010
The authors thank the National Institutes of Health (NIH R01 GM60595 to PCB) and the Scottish Universities Life Sciences Alliance (SULSA to JBOM) for funding.Functionally analogous enzymes are those that catalyze similar reactions on similar substrates ...
Daniel E. Almonacid, Emmanuel R. Yera, John B. O. Mitchell, Patricia C. Babbitt, Christine A. Orengo, RA George, JA Gerlt, PC Babbitt, JA Gerlt, ME Glasner, GJ Bartlett, MY Galperin, H Hegyi, ACR Martin, PF Gherardini, AE Todd, AE Todd, Z Zhang, S Tsoka, SA Teichmann, TD Otto, NH Horowitz, RA Jensen, GA Petsko, RA Chiang, CS Wright, BW Matthews, SC Morris, N Nagano, CT Porter, C Andreini, C Andreini, GL Holliday, GL Holliday, SC-H Pegg, SC-H Pegg, N Nagano, AG Murzin, G Ausiello, H Berman, NM O'Boyle, P Jaccard, P Willett, TF Smith, CA Orengo, AG McDonald, ACR Martin, SB Needleman, M Kotera, Y Yamanishi, GL Holliday, L Maveyraud, J Pitarch, R Castillo, JC Hermann, Z Wang, AP Leech, DG Gourley, AW Roszak, LM Blomberg, A Matte, MM Benning, PC Babbitt, DL Scott, BW Segelke, YS Ho, YS Ho, ME Lowe, Y Bourne, RJ Kazlauskas, H van Tilbeurgh, GJ Bartlett, T Nakai, A Zajc, E Ortlund, AB Hickman, TJ Wyckoff, CR Sweet, W Plaga, V Leppänen, F Himo, M Mathieu, Y Modis, RF Doolittle, V Sangar, BE Shakhnovich, PW Lord, J Gasteiger, O Sacher, DARS Latino, DARS Latino, DARS Latino, Y Loewenstein, T Dandekar, R Overbeek, AJ Enright, EM Marcotte, M Pellegrini, JC Hermann, JC Hermann, ME Glasner, L Jiang, M Bashton, K Tipton, KA Olszewski, R Preißner, J Park, PR Mittl, S Lorenzen, A Fersht, M Errami, EO Cannon, M Rizzi, J Symersky, Y Devedjiev, AR Battersby, N Frankenberg, MA Mathews, HL Schubert, B Stec, L Ma, JE Murphy, EB Fauman, RH Hoff, F Wang   +124 more
core   +3 more sources

Advances in Microbubble Technologies for Food Sanitization: A Comprehensive Review

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 4, July 2025.
ABSTRACT Microbubble (MB) technology has emerged as a transformative tool in food sanitization, where it offers innovative solutions for ensuring food safety and quality. The technology has a proven record of reducing dependency on chemicals for disinfecting food, which contributes to food safety.
Akash Patil, Sandeep B. Somvanshi, Manoj Sawale, Krunal Desai, Ferhan Ozadali, Patnarin Benyathiar, Dharmendra K. Mishra   +6 more
wiley   +1 more source

Molecular insights into the niche of harmful brown tides [PDF]

, 2011
Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution September 2011Recurrent brown tide blooms caused by the harmful alga ...
Wurch, Louie L.
core   +1 more source

Temperature–Photoperiod Interaction in Rice Phenology for Climate Adaptation: Insights Into Glycerate‐Associated Metabolic Responses

Physiologia Plantarum, Volume 177, Issue 4, July/August 2025.
ABSTRACT Rice heading date is tightly regulated by photoperiod and temperature, which are critical environmental cues for climate adaptation. While photoperiodic control of flowering has been well characterized, the molecular and metabolic mechanisms underlying temperature responses and their interaction with photoperiod remain unclear.
Hyeon‐Seok Lee, Ju‐Hee Kim, So‐Hye Jo, Seo‐Yeong Yang, Jae‐Kyeong Baek, Yeong‐Seo Song, Ji‐young Shon, Nam‐Jin Chung   +7 more
wiley   +1 more source

Extra-Mitochondrial CU/Zn Superoxide Dismutase (SOD1) Is Dispensable for Protection Against Oxidative Stress but Mediates Peroxide Signaling in Saccharomyces Cerevisiae [PDF]

, 2019
Cu/Zn Superoxide Dismutase (Sod1) is a highly conserved and abundant metalloenzyme that catalyzes thedisproportionation of superoxide radicals into hydrogen peroxide and molecular oxygen.
Andersen, Joshua L., Bolaji, Naimah, Chandrasekharan, Bindu, Colin, Alyson E., Montllor-Albalate, Claudia, Outten, Franklin W., Reddi, Amit R.   +6 more
core   +1 more source