Hydrochlorothiazide combined with exercise training attenuates blood pressure variability and renal dysfunctions in an experimental model of hypertension and ovarian hormone deprivation. [PDF]
FASEB BioadvHydrochlorothiazide plus combined exercise training provides superior benefits compared to medication alone in female spontaneously hypertensive rats subjected to ovarian hormone deprivation. This combined approach significantly reduced blood pressure variability, improved inflammatory and redox profiles, and provided functional and morphological ...
Petrica Neves P +6 more
europepmc +3 more sources
Hydrochlorothiazide in CLDN16 mutation [PDF]
Nephrology Dialysis Transplantation, 2006 Hydrochlorothiazide (HCT) is applied in the therapy of familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC) caused by claudin-16 (CLDN16) mutation. However, the short-term efficacy of HCT to reduce hypercalciuria in FHHNC has not yet been demonstrated in a clinical trial.Four male and four female patients with FHHNC and CLDN16 ...
Zimmermann, Bettina +6 more
openaire +5 more sources
Drug Use on Mont Blanc: A Study Using Automated Urine Collection [PDF]
, 2016 Mont Blanc, the summit of Western Europe, is a popular but demanding high-altitude ascent. Drug use is thought to be widespread among climbers attempting this summit, not only to prevent altitude illnesses, but also to boost physical and/or psychological
Botre', Francesco +10 more
core +7 more sources
Hot-melt co-extrusion for the production of fixed-dose combination products with a controlled release ethylcellulose matrix core [PDF]
, 2014 A
De Beer, Thomas +7 more
core +2 more sources
Hydrochlorothiazide and risk of melanoma subtypes [PDF]
Pharmacoepidemiology and Drug Safety, 2021 AbstractBackgroundHydrochlorothiazide (HCTZ), a common diuretic known to be photosensitizing and previously associated with non‐melanoma skin cancer, was recently reported to be associated with two melanoma subtypes, nodular and lentigo, among residents of Denmark.
Laurel A. Habel +4 more
openaire +4 more sources
Olmesartan-based monotherapy vs combination therapy in hypertension: A meta-analysis based on age and chronic kidney disease status. [PDF]
, 2017 Antihypertensive monotherapy is often insufficient to control blood pressure (BP). Several recent guidelines advocate for initial combination drug therapy in many patients. This meta-analysis of seven randomized, double-blind studies (N = 5888) evaluated
Bakris, George +3 more
core +1 more source
Is early and fast blood pressure control important in hypertension management? [PDF]
, 2018 Control of blood pressure (BP) in hypertension is recognized as a key measure in the management of cardiovascular (CV) risk and is a cornerstone of preventive strategies. It is not defined, however, whether an initiation of the antihypertensive treatment
Gallo, Giovanna +2 more
core +1 more source
Versatility of NaCl transport mechanisms in the cortical collecting duct [PDF]
, 2017 Versatility of NaCl transport mechanisms in the cortical collecting duct. Am J Physiol Renal Physiol 313: F1254 –F1263, 2017. First published September 6, 2017; doi:10.1152/ajprenal.00369.2017.—The cortical collecting duct (CCD) forms part of the ...
Crambert, Gilles, Edwards, Aurelie
core +1 more source
Hydrochlorothiazide reduces urinary calcium excretion in a child with Lowe syndrome. [PDF]
, 2015 There is a growing recognition that children with Lowe syndrome are at risk of nephrocalcinosis and nephrolithiasis from hypercalciuria. Increased fluid intake and correction of metabolic acidosis have remained the focus for intervention but are not ...
Butani, Lavjay
core +1 more source
Additional risk factors associated with symptomatic hydrochlorothiazide-induced hyponatremia in hypertensive patients [PDF]
, 2020 Background. Hydrochlorothiazide is a cheap and effective antihypertensive agent but may cause hyponatremia. Even though several risk factors for hydrochlorothiazide-induced hyponatremia have been reported, this study aimed to evaluate additional risk ...
Chattakul, Paiboon +12 more
core +2 more sources