Results 91 to 100 of about 35,744 (252)

Natural History of Idiosyncratic Drug‐Induced Liver Injury and Prognostic Models

open access: yesLiver International, Volume 45, Issue 6, June 2025.
ABSTRACT Background and Aims: Drug‐induced liver injury (DILI) remains a leading cause of acute liver failure worldwide. Drugs such as isoniazid, alone or in combination with other anti‐tuberculosis drugs, as well as a growing number of herbal and complementary medicines, have been implicated in most cases of acute liver failure in registry studies ...
Harshad C. Devarbhavi, Raúl J. Andrade
wiley   +1 more source

Oxidação Eletroquímica de Anlodipino e Hidroclorotiazida Sobre o Eletrodo de Diamante Dopado com Boro: Potencialidade de Determinação Simultânea em Urina

open access: yesOrbital: The Electronic Journal of Chemistry, 2015
The present study was undertaken to evaluate the use of boron-doped diamond The present study was undertaken to evaluate the use of boron-doped diamond electrode in the simultaneous voltammetric determination of antihypertensives amlodipine and ...
Guilherme Roberto Mansano   +1 more
doaj   +3 more sources

SIMULTANEOUS DETERMINATION OF CARVEDILOL AND HYDROCHLOROTHIAZIDE IN PHARMACEUTICAL DOSAGE FORM BY FIRST ORDER DERIVATIVE UV SPECTROPHOTOMETRY [PDF]

open access: yes, 2015
Objective: To develop an accurate, precise and linear UV spectrophotometry method for simultaneous determination of Carvedilol and Hydrochlorothiazide in Co-Dilatrol® tablet and validate as per ICH guidelines.Methods: Derivative spectrophotometric ...
Mali, Audumbar Digambar
core  

Generic sample preparation combined with high-resolution liquid chromatography- time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories [PDF]

open access: yes, 2010
A unification of doping-control screening procedures of prohibited small molecule substances—including stimulants, narcotics, steroids, ß2-agonists and diuretics—is highly urgent in order to free resources for new classes such as banned proteins ...
Georgakopoulos, C.G.   +4 more
core   +3 more sources

Acute hepatocellular and cholestatic injury during therapy with hydrochlorothiazide - clinicohistopathologic findings: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Hydrochlorothiazide and thiazide-like diuretics are considered first-line drugs for initial therapy in uncomplicated arterial hypertension. Acute cholecystitis is a well-known complication during treatment with thiazide, and these drugs are ...
Grilli Elisabetta   +8 more
doaj   +1 more source

SIMULTANEOUS ESTIMATION OF TELMISARTAN AND HYDROCHLOROTHIAZIDE BY DERIVATIVE SPECTROSCOPY [PDF]

open access: yes, 2015
Objective: The objective of this investigation is to present the simple and sensitive method for the analysis of Telmisartan and Hydrochlorothiazide and apply the proposed method for the analysis of said drugs in pharmaceutical formulations.Methods ...
Gajbhiye, Asmita   +3 more
core  

Perspektivy klinicheskogo primeneniyanovoy fiksirovannoy kombinatsii -preparata Ko-Eksforzh v lecheniiarterial'noy gipertonii

open access: yesКардиоСоматика, 2011
Summary. This review is concerned with improving of blood pressure (BP) control in patients with arterial hypertension (AH). The reasons for the low treatment compliance and combined antihypertensive therapy benefits are analyzed. Data for futility of an
Marina Gennad'evna Bubnova
doaj  

Three new hydrochlorothiazide cocrystals: Structural analyses and solubility studies [PDF]

open access: yes, 2016
YesHydrochlorothiazide (HCT) is a diuretic BCS class IV drug with poor aqueous solubility and low permeability leading to poor oral absorption. The present work explores the cocrystallization technique to enhance the aqueous solubility of HCT.
Aakeröy   +57 more
core   +1 more source

Preparation, optimization and characterization of multiple unit microspheres containing kollidone SR

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
The present investigation described the influence of viscosity and drug: Polymer ratio on Hydrochlorothiazide release. Floating microspheres loaded with hydrochlorothiazide were prepared by Emulsion solvent evaporation method.
Marvin I Patel   +2 more
doaj   +1 more source

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