Results 91 to 100 of about 22,036 (201)

Efficacy and Safety of a Single‐Pill Triple Combination of Valsartan, Amlodipine, and Chlorthalidone in Patients With Essential Hypertension Inadequately Controlled on Dual Therapy With Valsartan and Amlodipine: A Randomized, Double‐Blind, Multicenter, Phase 3 Trial

The Journal of Clinical Hypertension, Volume 28, Issue 9, September 2026.
ABSTRACT Many hypertensive patients require three or more antihypertensive agents to achieve target blood pressure. This randomized, double‐blind, multicenter phase 3 trial conducted in South Korea evaluated the efficacy and safety of a single‐pill triple combination therapy with valsartan (Val), amlodipine (Aml), and chlorthalidone (CTD) in patients ...
In‐Jeong Cho, Soon Jun Hong, Min Gyu Kong, Sang‐Ho Jo, Eun Joo Cho, Cheol Ung Choi, Jung Hyun Choi, Dae‐Hee Kim, Ju Han Kim, Sang‐Hyun Ihm, Wook Bum Pyun   +10 more
wiley   +1 more source

Role of comorbidities and medication on immunotherapy efficacy in cSCC: A DeCOG multicentre analysis

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 9, Page 1525-1534, September 2026.
Immunosuppressive disease was associated with reduced overall survival, while anticoagulant use was linked to prolonged progression‐free survival in advanced cutaneous squamous cell carcinoma treated with immune checkpoint inhibitors. Host‐related factors may modulate immunotherapy efficacy and warrant prospective validation.
Glenn Geidel, Sabrina Bänsch, Laura Adam, Nathan Fekade, Alessandra Rünger, Tim Zell, Daniel J. Smit, Julian Kött, Isabel Heidrich, Michael Weichenthal, Selma Ugurel, Ulrike Leiter, Peter Mohr, Alexandra Geusau, Stephan Grabbe, Markus V. Heppt, Ralf Gutzmer, Jochen Utikal, Jan‐Christoph Simon, Sebastian Haferkamp, Laura Susok, Bastian Schilling, Edgar Dippel, Imke von Wasielewski, Jessica C. Hassel, Carola Berking, Stefan W. Schneider, Christoffer Gebhardt   +27 more
wiley   +1 more source

Pharmacokinetics of Orally Administered Clonidine in Dogs

Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 5, Page 450-456, September 2026.
ABSTRACT Clonidine is an α‐2 agonist shown to be both well tolerated and useful in the treatment of canine fear‐based disorders, although it is perceived to have a short duration of action. Clonidine is available in regular release and extended‐release formulations, but canine pharmacokinetic (PK) and pharmacodynamic (PD) data on any clonidine ...
Kevin Pflaum, Julia Albright, Sherry Cox, Joe Smith   +3 more
wiley   +1 more source

Hydrochlorothiazide combined with exercise training attenuates blood pressure variability and renal dysfunctions in an experimental model of hypertension and ovarian hormone deprivation

FASEB BioAdvances
Considering that blood pressure variability (BPV) has been associated with damage to target organs such as the kidneys, this study aimed to investigate the effects of the association of hydrochlorothiazide (HCTZ) combined with exercise training (CET) on ...
Pietra Petrica Neves, Maycon Junior Ferreira, Tânia Plens Shecaira, Marina Rascio Henriques Dutra, Débora Conte Kimura, Guiomar Nascimento Gomes, Kátia De Angelis   +6 more
doaj   +1 more source

Methyldopa and Hydrochlorothiazide Compared with Reserpine and Hydrochlorothiazide in Hypertension [PDF]

BMJ, 1963
T M, AGNEW, R O, IRVINE, J D, NORTH
openaire   +2 more sources

Zinc, Hydrochlorothiazide and Sexual Dysfunction.

, 1995
This study was designed to test the hypothesis that hydrochlorothiazide a diuretic used to treat hypertension depletes body zinc and thereby cause sexual dysfunction.
Khedun, S.M.
core   +2 more sources

Hydrochlorothiazide [PDF]

AMA Journal of Ethics, 2017
openaire   +2 more sources

Hydrochlorothiazide and Hydroflumethiazide [PDF]

Postgraduate Medical Journal, 1960
openaire   +2 more sources

Dual antihypertensive strategies: A real-world comparative study of efficacy and safety of fixed-dose combinations in a tertiary care setting

Perspectives in Clinical Research
Aim: The aim of this study was to evaluate the comparative efficacy and safety of fixed-dose combinations of amlodipine 5 mg + hydrochlorothiazide 12.5 mg (A+H) (Group 1), telmisartan 40 mg + hydrochlorothiazide 12.5 mg (T+H) (Group 2), and ramipril 5 mg
Madhumita Dixit, Rakesh Chandra Chaurasia, Dwividendra Kumar Nim, Manoj Kumar Mathur   +3 more
doaj   +1 more source

Zofenopril plus hydrochlorothiazide combination in the treatment of hypertension

, 2016
IntroductionZofenopril is a highly lipophilic ACE inhibitor, characterized by long-lasting tissue penetration and sustained cardiac ACE inhibition, indicated for the treatment of hypertension and myocardial infarction.
Markova, Rostislava; Medical University of Varna, Kapitanska, Polina; Medical University of Varna, Shangova, Kaloyana; Medical University of Varna, Hristov, Lyubomir; Department of Internal Medicine, MHAT - Omurtag   +3 more
core   +1 more source