Results 1 to 10 of about 128,989 (341)

Early low-dose hydrocortisone is associated with a reduced risk of bronchopulmonary dysplasia in infants born at less than 26 weeks' gestational age [PDF]

open access: yesFrontiers in Pediatrics
ObjectiveTo determine whether administering low-dose hydrocortisone early in treatment reduces the risk of bronchopulmonary dysplasia (BPD) in infants born before 26 weeks of gestationStudy designThis retrospective case-control study compared the ...
Fang Yao   +10 more
doaj   +2 more sources

Hydrocortisone treatment is associated with early recovery from severe septic shock in patients with obstructive pyelonephritis due to upper urinary tract stone [PDF]

open access: yesBJUI Compass
Objectives The administration of hydrocortisone in patients with severe septic shock contributes to early recovery in intensive care. The purpose of this study was to evaluate the effect of hydrocortisone on early recovery from severe septic shock in ...
Isamu Otsuka   +6 more
doaj   +2 more sources

Research progress on therapeutic effect and mechanism of hydrocortisone on sepsis [PDF]

open access: yesCellular, Molecular and Biomedical Reports, 2023
Sepsis has remained a high mortality rate worldwide. Endothelial cell dysfunction is closely associated with the development of sepsis. Hydrocortisone has potent immunological and antitoxic effects, and thus it is frequently used in the treatment of ...
Yicen Long   +4 more
doaj   +1 more source

Comparison of Hydrocortisone Continuous Rate Infusion and Prednisolone or Dexamethasone Administration for Treatment of Acute Hypoadrenocortical (Addisonian) Crisis in Dogs

open access: yesFrontiers in Veterinary Science, 2022
ObjectivesTo determine whether administration of intravenous hydrocortisone is a safe and effective alternative treatment in comparison to the traditional treatment with prednisolone/dexamethasone in dogs presenting with Addisonian crisis; and to assess ...
Athanasia Mitropoulou   +3 more
doaj   +1 more source

Stability of Hydrocortisone in Oral Powder Form Compounded for Pediatric Patients in Japan

open access: yesPharmaceutics, 2021
Hydrocortisone has been utilized in the management of adrenal insufficiency. For pediatric patients, the commercially available enteral form of hydrocortisone tablets (Cortoril®) is administered in powder form after being compounded by a pharmacist ...
Jumpei Saito   +8 more
doaj   +1 more source

Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway

open access: yesBMC Pharmacology and Toxicology, 2023
Background The anti-osteosarcoma effects of hydrocortisone and thiram, an inhibitor of type 2 11ß-hydroxysteroid dehydrogenase (11HSD2), have not been reported.
You Zhang   +5 more
doaj   +1 more source

Post‐Cardiac Arrest Hydrocortisone Use Ameliorates Cardiac Mitochondrial Injury in a Male Rat Model of Ventricular Fibrillation Cardiac Arrest

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Steroid use after cardiac arrest has been reported to improve survival and neurological outcome in cardiac arrest survivors. The study aimed to evaluate the effect of post‐arrest hydrocortisone use on myocardial damage and cardiac ...
Min‐Shan Tsai   +6 more
doaj   +1 more source

Association of mortality with fludrocortisone addition to hydrocortisone treatment among septic shock patients: a propensity score matching analysis

open access: yesFrontiers in Medicine, 2023
BackgroundSeveral clinical trials of corticosteroids have been carried out in the treatment of septic shock, however, the therapeutic effect of the most widely used hydrocortisone is still controversial, and no studies have directly compared ...
Xiaoxiao Cheng   +4 more
doaj   +1 more source

Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]

open access: yes, 2005
Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Anderson   +46 more
core   +2 more sources

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