Results 71 to 80 of about 164,153 (386)

Adrenal Insufficiency under Standard Dosage of Glucocorticoid Replacement after Unilateral Adrenalectomy for Cushing’s Syndrome

Case Reports in Endocrinology, 2016
Glucocorticoid replacement is needed for patients after adrenal surgery for Cushing’s syndrome; however, the adequate dosage is not easily determined.
Kentaro Fujii, Kazutoshi Miyashita, Isao Kurihara, Ken Hiratsuka, Seiji Sato, Kenichi Yokota, Sakiko Kobayashi, Hirotaka Shibata, Hiroshi Itoh   +8 more
doaj   +1 more source

Hydrocortisone and ulinastatin for miliary tuberculosis-induced septic shock and adult respiratory distress syndrome in the intensive care unit

CHRISMED Journal of Health and Research, 2020
Hydrocortisone and ulinastatin are anti-inflammatory agent. We hereby report the case of a patient of sputum-positive miliary pulmonary tuberculosis that developed adult respiratory distress syndrome with septic shock.
Niraj Kumar Keyal, Manish Nakarmi
doaj   +1 more source

Effect of low-dose hydrocortisone and inhaled nitric oxide on inflammatory mediators and local pulmonary metalloproteinases activity in LPS-induced sepsis in piglets

Scientific Reports, 2023
Hospital mortality in sepsis varies between 30–45%. It has been shown that administration of inhaled nitric oxide (iNO) and intravenous corticosteroid in a porcine endotoxemia model attenuated the systemic inflammatory response.
Liliana Kiczak, Urszula Pasławska, Waldemar Goździk, Barbara Adamik, Marzena Zielińska, Stanisław Zieliński, Kacper Nowak, Michał Płóciennik, Jacek Bania, Aleksandra Tabiś, Marcin Nowak, Robert Pasławski, Claes Frostell   +12 more
doaj   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Preventive efficacy of hydrocortisone enema for radiation proctitis in rectal cancer patients undergoing short-course radiotherapy: a phase II randomized placebo-controlled clinical trial [PDF]

Annals of Coloproctology
Purpose This study aimed to investigate the efficacy of hydrocortisone enema in preventing radiation proctitis in patients with rectal cancer undergoing short-course radiotherapy (SCRT). Methods This phase II randomized controlled trial enrolled patients
Mohammad Mohammadianpanah, Maryam Tazang, Nam Phong Nguyen, Niloofar Ahmadloo, Shapour Omidvari, Ahmad Mosalaei, Mansour Ansari, Hamid Nasrollahi, Behnam Kadkhodaei, Nezhat Khanjani, Seyed Vahid Hosseini   +10 more
doaj   +1 more source

Potential metabolomic biomarkers for the identification and diagnosis of type A acute aortic dissection in patients with hypertension

Frontiers in Cardiovascular Medicine, 2022
ObjectivesMost patients with acute aortic dissection (AAD) have a history of hypertension. Diagnosis of AAD in patients with hypertension at an early stage is complicated and challenging.
Xiao-Bin Hao, Xiao-Bin Hao, Yue Han, Er-Ru Ni, Ming-Cai Ye, Gang Li, Xi-Jie Wu, Hai-Feng Qiang, Jun Zhao   +8 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Cardiac and vascular effects of low-dose steroids during the early phase of septic shock: An echocardiographic study

Frontiers in Cardiovascular Medicine, 2022
BackgroundLow-dose steroids are known to increase arterial pressure during septic shock through restoration of vasopressor response to norepinephrine. However, their effects on cardiac performance and ventriculo-arterial coupling (VAC) have never been ...
François Bagate, François Bagate, Alexandre Coppens, Paul Masi, Paul Masi, Nicolas de Prost, Nicolas de Prost, Nicolas de Prost, Guillaume Carteaux, Guillaume Carteaux, Guillaume Carteaux, Keyvan Razazi, Keyvan Razazi, Armand Mekontso Dessap, Armand Mekontso Dessap, Armand Mekontso Dessap   +15 more
doaj   +1 more source

Pre-hospital management of acute Addison’s Disease – Audit of patients attending a referral hospital in a regional area [PDF]

, 2019
Context: Adrenal crises (AC) cause morbidity and mortality in patients with Addison’s disease [primary adrenal insufficiency (PAI)]. Patient-initiated oral stress dosing, with parenteral hydrocortisone, is recommended to avert ACs. While these should be
Goubar, Thomas, McGrath, Shaun, Rushworth, R Louise, Torpy, David J   +3 more
core   +1 more source

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome: results of a randomized controlled trial

Critical Care, 2016
BackgroundAuthors of recent meta-analyses have reported that prolonged glucocorticoid treatment is associated with significant improvements in patients with severe pneumonia or acute respiratory distress syndrome (ARDS) of multifactorial etiology.
S. Tongyoo, C. Permpikul, W. Mongkolpun, Veerapong Vattanavanit, Veerapong Vattanavanit, Suthipol Udompanturak, M. Koçak, G. Meduri   +7 more
semanticscholar   +1 more source