Results 71 to 80 of about 96,281 (281)

Extracellular Matrix Viscoelasticity Regulates Mammary Branching Morphogenesis

Advanced Science, EarlyView.
This study shows that mammary branching morphogenesis is regulated by extracellular matrix (ECM) stress relaxation. Slow stress‐relaxing matrices promote branching through focal adhesion signaling, collagen fiber alignment, and cell contractions, whereas fast stress‐relaxing matrices impair branching and collagen alignment.
Daniella I. Walter, Juliette W. Moore, Abhishek Sharma, Ryan S. Stowers   +3 more
wiley   +1 more source

Brillouin Microscopy of Breast tumor Spheroids On‐a‐Chip: Mechanical and Transcriptional Responses to Microfluidic‐Induced Rapid Deformations

Advanced Science, EarlyView.
Brillouin‐Raman Microspectroscopy on‐a‐Chip (BRmS) enables real‐time analysis of breast tumor spheroids in microfluidic channels. Following cyclical deformations, MCF10.DCIS.com spheroids are captured in recovery traps and imaged with BRmS. The applied deformations trigger a stiffening response marked by increased frequency shifts, elevation of the ...
Mona Makkieh, Alessandra Anna Passeri, Davide Lazzari, Stefano Marchesi, Andrea Disanza, Rafal Khaled Ahmad Salem, Francesco Bonacci, Camillo Mazzella, Emanuele Martini, Mattia Tonani, Leonardo Donati, Edoardo Bellini, Hind Abdo, Judith Pineau, Serena Magni, Fabrizio Orsenigo, Matthieu Piel, Daniele Fioretto, Sabata Martino, Maurizio Mattarelli, Giorgio Scita, Brenda J. Green, Silvia Caponi   +22 more
wiley   +1 more source

The Effect of Intravenous Hydrocortisone (1 or 2 mg/kg) on Postoperative Shivering in Cesarean Section with Spinal Anesthesia

مجله دانشکده پزشکی اصفهان, 2017
Background: Postoperative shivering is one of the most prevalent complications that several methods were used for controlling it. This study aimed to determine the effect of two doses of intravenous hydrocortisone (1 or 2 mg/kg) on postoperative ...
Azim Honarmand, Mohammadreza Reza Safavi, Anahita Hirmanpour, Soheila Afzali   +3 more
doaj  

The Effect of Hydrocortisone Treatment After Day Fourteen of Life on Preventing Bronchopulmonary Dysplasia in Preterm Infants [PDF]

Iranian Journal of Neonatology
Background: This study aimed to evaluate whether administering low-dose hydrocortisone after the first fourteen days of life affects the incidence of bronchopulmonary dysplasia (BPD), mortality, and other short-term complications in mechanically ...
Motahhareh Talebian, tahereh Esmailnia Shirvani, Mamak Shariat, Roya Taheri Tafti   +3 more
doaj   +1 more source

Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function [PDF]

, 2015
Susan J. Burke, Amanda L. May, Robert C. Noland, Danhong Lu, Marcela Briššová, Alvin C. Powers, Elizabeth Sherrill, Michael D. Karlstad, Shawn R. Campagna, Jacqueline M. Stephens, J. Jason Collier   +10 more
openalex   +1 more source

Evaluation of Effectiveness of Dexamethasone versus Hydrocortisone in Reducing Hospital Length, Peak Expiratory Flow,Oxidative Stress Factors and Inflammatory Mediators in Chronic Obstructive Pulmonary Disease (COPD) Exacerbation Patients: A Randomized Controlled Trial [PDF]

, 2022
Moslem Sedaghattalab, Doustimotlagh Amir Hossein, Ardashir Afrasiabifar, hosseini ahad   +3 more
openalex   +1 more source

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

General theory of inflammation: patient self-administration of hydrocortisone safely achieves superior control of hydrocortisone-responding disorders by matching dosage with symptom intensity

Journal of Inflammation Research, 2019
John B Irwin,1 AL Baldwin,2 Virgil I Stenberg31Private Practice, Tarrington, CT, USA; 2Department of Physiology, School of Medicine, University of Arizona School of Medicine, Tucson, AZ, USA; 3University of North Dakota, Grand Forks, ND, USA†John ...
Irwin JB, Baldwin AL, Stenberg VI
doaj  

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

Advanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim, Hanjun Hwangbo, ByungJoon Choi, Dogeon Yoon, GeunHyung Kim   +4 more
wiley   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source