Results 141 to 150 of about 10,889,129 (322)

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing

Advanced Functional Materials, EarlyView.
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy, Chuan‐En Lu, Kai Liu, Audrey Gallud   +3 more
wiley   +1 more source

Hydrodynamic performance optimization and experimental verification of underwater glider based on parametric method. [PDF]

Sci Prog, 2022
Qin H, Li L, Li P, Wang X.
europepmc   +1 more source

Three‐Dimensional Hierarchical Nanowire‐Networks with Deep‐Focus Tolerance and Adhesion Robustness for Harsh‐Environment SERS Sensing

Advanced Functional Materials, EarlyView.
A 3D nanowire‐network SERS substrate with robust adhesion is developed, featuring pronounced z‐direction optical activity, ultralow detection limit (1.5 × 10−13 M), and excellent signal uniformity (RSD < 10%). Enabled by enhanced light scattering, increased optical density of states, and structural reinforcement, the substrate demonstrates stable, high‐
Jinglai Duan, Wentao Wang, Xiu Liang, Yongliang Zhang, Jie Liu, Yu Bai, Dangyuan Lei   +6 more
wiley   +1 more source

Numerical and Experimental Study of a Bio-Inspired Flapping Wing with Increasing Twist Angle Along the Wingspan

Machines
Inspired by the movements of sea turtle forelimbs, this study presents a bio-inspired underwater flapping wing with three degrees of freedom. This flapping wing mechanism can more accurately simulate the rotational motion of a sea turtle’s forelimbs to ...
Mingguang Gong, Jialei Li, Xuanning Zhang, Donghong Ning, Penglei Ma   +4 more
doaj   +1 more source

Mimicking Block Copolymer Self‐Assembly with One‐Pot Synthesized Polyphosphoester Gradient Copolymers

Advanced Functional Materials, EarlyView.
Degradable Polyphosphoester (PPE) gradient copolymers (GCPs) are synthesized via one‐pot copolymerization. We show that GCPs self‐assemble into nanostructures like polymersomes, effectively mimicking the behavior of traditional BCPs. The gradient strength is key, with softer gradients favoring micelles.
Suna Azhdari, Timo Rheinberger, Ulrich Mansfeld, Yorick Post, Jürgen Linders, Olga Koshkina, André H. Gröschel, Frederik R. Wurm   +7 more
wiley   +1 more source

Bioinspired Stabilization of Fluorescent Au@SiO2 Tracers for Multimodal Biological Imaging

Advanced Functional Materials, EarlyView.
This study demonstrates a bioinspired stabilization strategy for fluorescent gold‐silica nanoparticles. Inspired by natural biosilica maturation, high‐temperature calcination transforms the silica shells, preventing dissolution in cell culture media and intracellular environments.
Wang Sik Lee, Henry Lee, Patricia Taladriz‐Blanco, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Alke Petri‐Fink   +5 more
wiley   +1 more source

A Novel 10 MW Floating Wind Turbine Platform—SparFloat: Conceptual Design and Dynamic Response Analysis

Journal of Marine Science and Engineering
New conceptual designs for floating offshore wind platforms (FOWPs) are crucial for deep-sea wind power generation, increasing power output, lowering construction costs, and minimizing the risk of damage. While there have been various conceptual designs,
Yong Shen, Jian Liu, Xingchun Yan, Huaxing Liu, Yajie Li, Xikun Wang   +5 more
doaj   +1 more source

Nanodiamond‐Based Quantum Sensing Reveals Changes in Endo‐Lysosomal Activity of Stimulated Cardiac Fibroblasts in a Cellular Fibrosis Model

Advanced Functional Materials, EarlyView.
Quantum sensing reveals intricate patterns linking endo‐lysosomal maturation to cardiac fibrosis progression, highlighting complexity in cellular remodeling. This study investigates fibroblast‐to‐myofibroblast transition under cell aging, stiffness, and TGF‐β stimulation, comparing nanodiamond uptake, endo‐lysosomal dynamics, and free radical ...
Aldona Mzyk, Ezgi Yilmaz, Giovanni D Angelo, Kirstine Berg‐Sørensen   +3 more
wiley   +1 more source

Numerical Study on Hydrodynamic Performance of a Pitching Hydrofoil with Chordwise and Spanwise Deformation

Journal of Marine Science and Engineering
The hydrofoil plays a crucial role in tidal current energy (TCE) devices, such as horizontal-axis turbines (HATs), vertical-axis turbines (VATs), and oscillating hydrofoils.
Hengliang Qu, Xueyan Li, Xiaochen Dong
doaj   +1 more source

HYDRODYNAMIC PERFORMANCES OF SMALL SIZE SWATH CRAFT

Brodogradnja, 2015
The good seakeeping characteristics of SWATH hull form are very interesting for small working craft and pleasure boats. Intrinsic limitations as the low values of weight per inch of immersion and transversal and longitudinal instability, can be acceptable and successfully managed when the mission profile does not ask for significant load variation and ...
Bertorello, Carlo, Begovic, Ermina, Mancini, Simone   +2 more
openaire   +3 more sources