Results 41 to 50 of about 669,973 (330)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Stress corrosion cracking in Al-Zn-Mg-Cu aluminum alloys in saline environments [PDF]

, 2012
Copyright 2013 ASM International. This paper was published in Metallurgical and Materials Transactions A, 44A(3), 1230 - 1253, and is made available as an electronic reprint with the permission of ASM International.
A. Berzin, A. Kolics, A. Turnbull, A.H. Le, A.H. Le, A.J. McEvily, A.K. Vasudevan, A.S. Tetelman, B. Jegdic, B. Sakar, B.J. Connelly, B.J. Connelly, C.A. Loto, C.M. Liao, D.J. Sullivan, D.M. Drazic, E.A. Starke, F.E. Watkinson, F.P. Ford, F.S. Lin, G. M. Scamans, G.A. Young, G.A. Young, G.M. Scamans, G.M. Scamans, H. Gruhl, H. Kim, H.F. Jong de, J. Onoro, J. Onoro, J. Robinson, J. Zhang, J.K. Park, J.P. Nordin, J.R. Scully, K. Kitamura, K. Komai, K.G. Kent, K.P. Wong, K.R. Cooper, K.R. Cooper, K.R. Cooper, L. Tomcsanyi, L.H. Chambers, L.P. Huang, M. Abe, M. Cook, M. Landkof, M. Metikos-Hukovic, M. Watanabe, M.O. Speidel, M.V. Hyatt, N. J. Henry Holroyd, N. Lampeas, N.J.H. Holroyd, N.J.H. Holroyd, N.J.H. Holroyd, O.D. Sherby, P. Martin, P.M. Natishan, R. Hermann, R.C. Doward, R.S. Pathania, R.T. Foley, R.T. Foley, S. Lee, S. Mostovoy, S. Ohsaki, S. Ohsaki, S. Osaki, S. Pyun, S. Pyun, T. Ishikawa, T. Magnin, T. Ohnishi, T. Oka, T.H. Nguyen, T.H. Nguyen, T.H. Sanders, W. Gruhl, Y. Choi, Z.A. Foroulis   +81 more
core   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

AVALIAÇÃO DA QUALIDADE DE CREMES DERMATOLÓGICOS MANIPULADOS NA CIDADE DE MARÍLIA, SP

Colloquium Vitae, 2009
The magistral pharmacy represents an important segment in the national market of pharmacy and since the RDC 67/2007, will have to follow the new rules to guarantee more security, quality and efficacy of the manipulated formulae.
Leandra Aparecida B. Rigato, André Ribeiro Collins Cunha, Livian Maria de Angelo Zilotti, Patricia Silva Shimabuku, Marcos Alberto Zocoler   +4 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Hydrogen Ion Concentration of Sheet Making Water and Its Relationship to the Hygroexpansion of Paper [PDF]

, 1967
The hygroexpansivity of paper is of particular importance in the paper industry. As paper dimensions become more critical, the problem of hygroexpansivity in paper necessarily becomes more critical.
Rischar, James M.
core   +1 more source

Hydrogen ion passivation of multicrystalline silicon solar cells

, 1987
It has been recognized that hydrogen can be chosen to passivate the defects present in polycrystalline materials. Technically, the best approach is to use hydrogen ion implantation at low energy (0.5 to 5 keV) by means of a Kaufman or similar type ion ...
Ababou, Y., Barhdadi, A., Muller, J.C., Siffert, P.   +3 more
core   +3 more sources

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Kinetic and Thermodynamic Study of Oxidative Decolourisation of a Typical Food Dye (Tartrazine) in an Aqueous Environment

Journal of Applied Sciences and Environmental Management, 2020
The study was carried out to describe the kinetics and thermodynamics of hydrogen peroxide oxidation of a typical food dye (Tartrazine). The effect of different operational factors were investigated spectrophotometricallyat wavelength460 nm under pseudo
F.O. Okeola, E.O. Odebunmi, M.A. Amoloye, H.F. Babamale, S. Thema, J.O. Abdulsalam   +5 more
doaj   +1 more source

The Value of Rumex Acetosella as an Acid Indicator [PDF]

, 1931
Among laymen and agriculturists it is a common expression that certain spots in a field are acid. The term acid spots has come to be used more and more since soil reaction has been shown to have some bearing upon the soil preferences of many plants ...
Artist, Russell
core   +1 more source