Results 41 to 50 of about 1,523,076 (289)

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Highly thermally conductive composite films by the rational assembly of aramid nanofibers with low-dimensional nanofillers

open access: yesJournal of Materials Research and Technology
Highly efficient thermal management of electronic devices has grown in significance with the burgeoning of semiconductor technology and 5th generation communication.
Xuyun Liang   +7 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Thermogravimetric Analysis of Char Waste from the Air Gasification of Empty Fruit Bunch Briquette.

open access: yesMATEC Web of Conferences, 2014
The thermal decomposition behavior of char waste produced from the air gasification of Empty Fruit Bunch (EFB) briquette was examined using thermogravimetric analysis (TGA).
Nyakuma Bemgba Bevan   +4 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Dimensions, structure, and morphology variations of carbon-based materials for hydrogen storage: a review

open access: yesDiscover Nano
The swift and far-reaching evolution of advanced nanostructures and nanotechnologies has accelerated the research rate and extent, which has a huge prospect for the benefit of the practical demands of solid-state hydrogen storage implementation ...
Shadykulova Assyl   +2 more
doaj   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

open access: yesFEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni   +4 more
wiley   +1 more source

Deactivation mechanism for water splitting: Recent advances

open access: yesCarbon Energy
Hydrogen (H2) has been regarded as a promising alternative to fossil‐fuel energy. Green H2 produced via water electrolysis (WE) powered by renewable energy could achieve a zero‐carbon footprint.
Yansong Jia   +10 more
doaj   +1 more source

Effect of pore morphology and surface roughness on wettability of porous titania films

open access: yesMaterials Research Express, 2020
Surface hydrophobicity/hydrophilicity of titania (TiO _2 ) films, spin-coated on silicon wafers, were tuned by introducing surface mesopores with various morphologies using a triblock copolymer F38 as the template agent of different weight ratios via a ...
Bangyun Xiong   +6 more
doaj   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

open access: yesFEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper   +5 more
wiley   +1 more source

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